Chemokines and chemokine receptors: insights from human disease and experimental models of helminthiasis

Image 1Dr. Lucas Kraemer is graduated in Biological Sciences from UFMG (2015), MSc in Physiology and Pharmacology (2017) from UFMG and Ph.D. in Parasitology (2022) from UFMG, concentration area in Immunoparasitology. As an undergraduate student at the Laboratory of Immunology and Pulmonary Mechanics (UFMG), headed by Prof. Dr. Remo Castro Russo, he began his studies in immunology and inflammation of lung diseases. During his MSc, he studied the role of the CCR2 chemokine receptor in the experimental model of lung injury associated with acute pancreatitis. During the Ph.D., now under the supervision of Prof. Dr. Ricardo Toshio Fujiwara, head of the Laboratory of Immunology and Genomics of Parasites, and under the co-supervision of Prof. Dr. Remo Castro Russo, he studied the role of the atypical chemokine receptor ACKR2 in the immunoparasitological and pathophysiological aspects of experimental larval ascariasis.

Image 2Dr. Derek M. McKay is a Professor in the Department of Physiology and Pharmacology and a member of the Calvin, Joan and Phoebe Snyder Institute for Chronic Diseases at the Cumming School of Medicine, University of Calgary. Dr. McKay is Chair of the Gastrointestinal Research Group (GIRG) at the University of Calgary and Past-President Canadian Association of Gastroenterology (2016-2018). Dr. McKay was recruited to the University of Calgary on a Canada Research Chair in Intestinal Immunophysiology and was concurrently awarded an Alberta Heritage Foundation for Medical Research (AHFMR) Scientist Award. He has wide-ranging interests in intestinal physiology and pathophysiology, particularly related to inflammatory disease. Current projects in his laboratory include: analysis of the impact of infection with helminth parasites on mucosal immunity and concurrent inflammatory disease, cytokine regulation of intestinal epithelial barrier function, the role of epithelial mitochondria in the control of epithelial permeability and inflammatory disease, and characterization of helminth-derived immunomodulatory molecules.

Image 3Dr. Remo Castro Russo is Associate Professor of the Physiology and Biophysics Department from UFMG and head of the Laboratory of Pulmonary Immunology and Mechanics at the Institute of Biological Sciences/UFMG. With a Ph.D. in Immunology, he has a wide-ranging research interest related to pulmonary physiology, immunology, and pharmacology in acute and chronic lung diseases, particularly with a vast experience regarding the cytokine and chemokine systems. Current projects in his laboratory include: Role of lung mucosal immunology during pulmonary fibrosis, pulmonary pharmacology, and the role of cytokines and chemokines in physiology and disease (lung inflammation and infection, fibrosis and allergy, cancer and reproduction).

Image 4Dr. Ricardo Toshio Fujiwara is Associate Professor in the Department of Parasitology from UFMG and head of the Laboratory of Immunology and Parasite Genomics at the Institute of Biological Sciences/UFMG. He is affiliated member of the Brazilian Academy of Sciences (2012-2016) and Vice president of the Brazilian Society of Parasitology. Dr. Fujiwara has extensive experience in the field of Parasitology and Tropical Medicine, with emphasis on helminth immunology and the development of tools (diagnosis, vaccines and drugs) for the control of neglected diseases.

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