∗Department of Pharmacy, Nimes University Hospital, University of Montpellier, Nimes

†Desbrest Institute of Epidemiology and Public Health, University of Montpellier, INSERM, Montpellier

‡Pain Assessment and Treatment Centre, Nimes University Hospital, University of Montpellier, Nimes

§Laboratory of Health Economics and Law, Faculty of Pharmacy, University of Montpellier, Montpellier, France.

Address correspondence and reprint requests to Julie Jambon, PharmD, Pharmacie, CHU de Nîmes, place du professeur Robert Debré, 30029 NIMES Cedex 09, France; E-mail: [email protected]

Conflicts of Interest and Source of Funding: The authors have no conflicts of interest to declare. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Data are available upon reasonable request from the corresponding author.

Authors' contributions: All authors contributed to the study conception and design of the study. J.J. collected the data. G.L.-B. analyzed the data. All authors contributed to the interpretation of study results. The first draft of the manuscript was written by J.J., and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript. All the authors have approved its publication.

This study (ID-RCB 2017-A03171-52, ALGOGER) was approved by a French committee for the protection of persons, and the National Agency for the Safety of Medicines and Health Products (ANSM) was informed. It is registered at clinicaltrials.gov as NCT04006444.

According to French law for observational study, all patients included gave oral consent to participate in the study after being verbally informed and receiving an information letter.

The article was presented in the francophone congress of hospital pharmacy (HOPIPHARM) from May 15 to 17, 2019, in Marseille (https://www.synprefh.org/sites/www.synprefh.org/files/file/espace-congres/hopipharm/hopi2019_communications-retenues.pdf).

Digit ORCID of author: J.J.:0000-0002-6709-5337, C.C.: 0000-0002-9116-3184, C.R.-M.: 0000-0001-6300-4330, É.V.: 0000-0002-6050-3246, G.L.-B.: 0000-0001-5191-0977.