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Gomaa, M. (2022). Potential applications of inorganic silver nanoparticles (AgNPs) in parasitic diseases. Parasitologists United Journal, 15(1), 5-21. doi: 10.21608/PUJ.2022.108173.1145

Maha Gomaa. "Potential applications of inorganic silver nanoparticles (AgNPs) in parasitic diseases". Parasitologists United Journal, 15, 1, 2022, 5-21. doi: 10.21608/PUJ.2022.108173.1145

Gomaa, M. (2022). 'Potential applications of inorganic silver nanoparticles (AgNPs) in parasitic diseases', Parasitologists United Journal, 15(1), pp. 5-21. doi: 10.21608/PUJ.2022.108173.1145

Gomaa, M. Potential applications of inorganic silver nanoparticles (AgNPs) in parasitic diseases. Parasitologists United Journal, 2022; 15(1): 5-21. doi: 10.21608/PUJ.2022.108173.1145

Article 2, Volume 15, Issue 1, April 2022, Page 5-21   PDF (586.53 K) Document Type: Review Article DOI: 10.21608/PUJ.2022.108173.1145Author Maha Gomaa Medical Parasitology Department, Faculty of Medicine, Alexandria University, Alexandria, EgyptAbstractParasitic diseases are globally distributed, leading to considerable morbidity and mortality especially in low
and middle-income countries. The current treatment strategies of parasitic infections face hard challenges
due to emergence of drug resistance and intolerable side effects. Therefore, the development of novel, safe
and effective anti-parasitic agents is urgently required. In this context, nanomaterials represent an efficient
tool to overcome the barriers observed in several conventional therapeutics. Nanotechnology has efficiently
provided tools enabling structural modifications in chemical compounds, empowering their highly desirable
selectivity and specificity. Among them, metal nanoparticles (NPs) have been significantly utilized as an
alternative therapeutic approach and/or efficient delivery system in a wide range of parasitic diseases. Due
to its extraordinary range of bactericidal properties and therapeutic abilities, AgNPs have become a part
of medical management of various diseases. Moreover, a number of plant species successfully employed
in AgNPs green synthesis, are ecofriendly efficient alternatives to chemically synthesized NPs. The current
review aims to shed light on AgNPs regarding their physiochemical properties, synthesis methods, and
potential applications in diagnosis, treatment, and protection against parasitic infections. Concerning the
last issue, their insecticidal activities paved the way for prevention of transmission of vector borne parasitic
diseases.Keywords AgNPs; anthelmintic; antiprotozoal; chemical synthesis; diagnosis; green synthesis; insecticidal; in vitro; in vivo

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