Gomaa, M. (2022). A Review on The Antiparasitic Properties of Inorganic Silver Nanoparticles (AgNps). Parasitologists United Journal, (), -. doi: 10.21608/puj.2022.108173.1145

Maha Mohamed Gomaa. "A Review on The Antiparasitic Properties of Inorganic Silver Nanoparticles (AgNps)". Parasitologists United Journal, , , 2022, -. doi: 10.21608/puj.2022.108173.1145

Gomaa, M. (2022). 'A Review on The Antiparasitic Properties of Inorganic Silver Nanoparticles (AgNps)', Parasitologists United Journal, (), pp. -. doi: 10.21608/puj.2022.108173.1145

Gomaa, M. A Review on The Antiparasitic Properties of Inorganic Silver Nanoparticles (AgNps). Parasitologists United Journal, 2022; (): -. doi: 10.21608/puj.2022.108173.1145

Articles in Press, Accepted Manuscript, Available Online from 28 February 2022   Document Type: Review Article DOI: 10.21608/puj.2022.108173.1145Author Maha Mohamed Gomaa Medical Parasitology Department, Faculty of Medicine, Alexandria University, Alexandria EgyptAbstractParasitic diseases are globally important, leading to considerable morbidity and mortality especially in low and middle income countries. The current treatment strategies of parasitic infections are facing hard challenges due to emergence of drug resistance and non-tolerable side effects in human beings. Therefore, the development of novel, safe and effective antiparasitic agents is the need of the hour. In this context, nanomaterials could represent an efficient solution to overcame the barriers found in several conventional therapeutics. Nanotechnology has efficiently provided tools that enable structural modifications in chemical compounds, empowering them with highly desirable selectivity and specificity. Among different nanomaterials, metal nanoparticles have been significantly studied as alternative tools to treat a wide range of parasitic diseases. Silver, due to its extraordinary range of bactericidal properties and therapeutic abilities, has been a part of medical management of various diseases since ancient times. It is a well-recognized fact that silver ions and silver-based compounds have a great microbial killing power. The current article is revising one of the important members of inorganic metal nanoparticles “silver nanoparticles; AgNps” regarding the physiochemical properties, the different methods of synthesis and insisting on their antiprotozoal, anthelmintic and insecticidal activities, either in vitro or in experimental studies. Different medically-important parasites, affected by AgNps were listed in this review. A number of plant species which were successfully-tried in green synthesis of AgNps, were also pointed out. In conclusion, biosynthesized and green synthesized AgNps are ecofriendly efficient alternatives of chemically-synthesized particles. They proved their antiparasitic potentials against a wide range of medically-important parasites in vitro and showed a safe employment in vivo. Further studies in vivo and on clinical based should be carried out.Keywords Silver nanoparticles (AgNps); Chemical and green synthesis; In vitro and in vivo studies; Antiprotozoal effects; Anthelmintic properties; Insecticidal potentials Main Subjects Protozoology

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