Title:Microwave-assisted C-C and C-Heteroatom Bond Formations in an Aqueous Medium
VOLUME: 8 ISSUE: 2
Author(s):Bijeta Mitra and Pranab Ghosh*
Affiliation:Department of Chemistry, University of North Bengal, District Darjeeling, West Bengal, Department of Chemistry, University of North Bengal, District Darjeeling, West Bengal
Keywords:C-hetero bond, C-C coupling, C-heteroatom, microwave, water, greener, aqueous medium, conventional reaction.
Abstract:In recent times, microwave-assisted chemistry has gained enormous attraction in organic synthesis owing to its versatile advantages such as avoidance of harsh reaction condition, increase of yield, elimination of by-product, shorter reaction time and removal of wastages. Besides, water as a reaction medium further includes more benefits as it eliminates all the drawbacks of toxic solvent, which may cause injuries for our mother earth. Furthermore, C-C and C-heteroatom bond formation reactions are very significant as most of the drug as well as bioactive compounds contain heterocycles or C-hetero bond, which is a key tool of chemistry. This article demonstrates the advancement on the topic of microwave assisted C-C and C-heteroatom bond formation reactions in aqueous medium.
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