Cell Type–Specific Nuclei Markers: The Need for Human Brain Research to Go Nuclear

Abbott, NJ, Rönnbäck, L, Hansson, E. 2006. Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci 7:41–53.
Google Scholar | Crossref | Medline | ISI Abraira, VE, Ginty, DD. 2013. The sensory neurons of touch. Neuron 79:618–39.
Google Scholar | Crossref | Medline Al-dalahmah, O, Sosunov, AA, Shaik, A, Ofori, K, Liu, Y, Vonsattel, JP others. 2020. Single-nucleus RNA-seq identifies Huntington disease astrocyte states. Acta Neuropathol Commun 8:19.
Google Scholar | Crossref | Medline Annovazzi, L, Mellai, M, Caldera, V, Valente, G, Schiffer, D. 2011. SOX2 expression and amplification in gliomas and glioma cell lines. Cancer Genomics Proteomics 8:139–47.
Google Scholar | Medline Armulik, AA, Genove, G, Betsholtz, C. 2011. Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev Cell 21:193–215.
Google Scholar | Crossref | Medline | ISI Bakken, TE, Hodge, RD, Miller, JA, Yao, Z, Nguyen, TN, Aevermann, B others. 2018. Single-nucleus and single-cell transcriptomes compared in matched cortical cell types. PLoS One 13:e0209648.
Google Scholar | Crossref Barbarese, E, Barry, C, Chou, CJ, Goldstein, DJ, Nakos, GA, Hyde-DeRuyscher, R others. 1988. Expression and localization of myelin basic protein in oligodendrocytes and transfected fibroblasts. J Neurochem 51:1737–45.
Google Scholar | Crossref | Medline Barnabé-Heider, F, Göritz, C, Sabelström, H, Takebayashi, H, Pfrieger, FW, Meletis, K others. 2010. Origin of new glial cells in intact and injured adult spinal cord. Cell Stem Cell 7:470–82.
Google Scholar | Crossref | Medline Bennett, ML, Bennett, FC, Liddelow, SA, Ajami, B, Zamanian, JL, Fernhoff, NB others. 2016. New tools for studying microglia in the mouse and human CNS. Proc Natl Acad Sci U S A 113:E1738–E1746.
Google Scholar | Crossref Berglund, L, Bjo, E, Oksvold, P, Fagerberg, L, Asplund, A, Szigyarto, CA others. 2008. A genecentric human protein atlas for expression profiles based on antibodies. Mol Cell Proteomics 7:2019–27.
Google Scholar | Crossref | Medline Birdsey, GM, Dryden, NH, Amsellem, V, Gebhardt, F, Sahnan, K, Haskard, DO others. 2008. Transcription factor ERG regulates angiogenesis and endothelial apoptosis through VE-cadherin. Blood 111:3498–506.
Google Scholar | Crossref | Medline Birdsey, GM, Shah, AV, Dufton, N, Reynolds, LE, Almagro, LO, Yang, Y others. 2015. The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling. Dev Cell 32:82–96.
Google Scholar | Crossref | Medline | ISI Booth, HDE, Hirst, WD, Wade-Martins, R. 2017. The role of astrocyte dysfunction in Parkinson’s disease pathogenesis. Trends Neurosci 40:358–70. doi:10.1016/j.tins.2017.04.001
Google Scholar | Crossref | Medline Braak, H, Rüb, U, Gai, WP, Del Tredici, K. 2003. Idiopathic Parkinson’s disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen. J Neural Transm 110:517–36.
Google Scholar | Crossref | Medline Butovsky, O, Jedrychowski, MP, Moore, CS, Cialic, R, Lanser, AJ, Gabriely, G others. 2014. Identification of a unique TGF-β-dependent molecular and functional signature in microglia. Nat Neurosci 17:131–43.
Google Scholar | Medline Buttgereit, A, Lelios, I, Yu, X, Vrohlings, M, Krakoski, NR, Gautier, EL others. 2016. Sall1 is a transcriptional regulator defining microglia identity and function. Nat Immunol 17:1397–406.
Google Scholar | Crossref | Medline Cai, Z, Qiao, P, Wan, C, Cai, M, Zhou, N, Li, Q. 2018. Role of blood-brain barrier in Alzheimer’s disease. J Alzheimers Dis 63:1223–34.
Google Scholar | Crossref Campbell, JG, Miller, DC, Cundiff, DD, Feng, Q, Litofsky, NS. 2015. Neural stem/progenitor cells react to non-glial CNS neoplasms. Springerplus 4:53.
Google Scholar | Crossref | Medline Carnevale, D, de Simone, R, Minghetti, L. 2007. Microglia-neuron interaction in inflammatory and diseases: role of cholinergic and noradrenergic systems. CNS Neurol Disord 6:388–97.
Google Scholar | Medline Carvey, PM, Hendey, B, Monahan, AJ. 2009. The blood brain barrier in neurodegenerative disease: a rhetorical perspective. J Neurochem 111:291–314.
Google Scholar | Crossref | Medline | ISI Chanmee, T, Ontong, P, Konno, K, Itano, N. 2014. Tumor-associated macrophages as major players in the tumor microenvironment. Cancers (Basel) 6:1670–90.
Google Scholar | Crossref | Medline Chen, C, Zhong, X, Smith, DK, Tai, W, Yang, J, Zou, Y others. 2019. Astrocyte-specific deletion of Sox2 promotes functional recovery after traumatic brain injury. Cereb Cortex 29:54–69.
Google Scholar | Crossref | Medline Chen, W, Guo, Y, Walker, EJ, Shen, F, Jun, K, Oh, SP others. 2013. Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain. Arterioscler Thromb Vasc Biol 33:305–10.
Google Scholar | Crossref Cheng, J, Korte, N, Nortley, R, Sethi, H, Tang, Y, Attwell, D. 2018. Targeting pericytes for therapeutic approaches to neurological disorders. Acta Neuropathol 136:507–23. doi:10.1007/s00401-018-1893-0
Google Scholar | Crossref | Medline Dammer, EB, Duong, DM, Diner, I, Gearing, M, Feng, Y, Lah, JJ others. 2013. Neuron enriched nuclear proteome isolated from human brain. J Proteome Res 12:3193–206.
Google Scholar | Crossref Daneman, R, Prat, A. 2015. The blood-brain barrier. Cold Spring Harb Perspect Biol 7:a020412.
Google Scholar | Crossref | Medline Daneman, R, Zhou, L, Kebede, AA, Barres, BA. 2010. Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature 468:562–6. doi:10.1038/nature09513
Google Scholar | Crossref | Medline Dewar, D, Underhill, SM, Goldberg, MP. 2003. Oligodendrocytes and ischemic brain injury. J Cereb Blood Flow Metab 23:263–74.
Google Scholar | SAGE Journals Dieriks, BV, Park, TIH, Fourie, C, Faull, RLM, Dragunow, M, Curtis, MA. 2017. α-Synuclein transfer through tunneling nanotubes occurs in SH-SY5Y cells and primary brain pericytes from Parkinson’s disease patients. Sci Rep 7:42984. doi:10.1038/srep42984
Google Scholar | Crossref Drouin-Ouellet, J, Sawiak, SJ, Cisbani, G, Kuan, W, Saint-pierre, M, Dury, RJ others. 2015. Cerebrovascular and blood-brain barrier impairments in Huntington’s disease: potential implications for its pathophysiology. Ann Neurol 78:160–77.
Google Scholar | Crossref | Medline Duan, W, Zhang, YP, Hou, Z, Huang, C, Zhu, H, Zhang, CQ others. 2016. Novel insights into NeuN: from neuronal marker to splicing regulator. Mol Neurobiol 53:1637–47.
Google Scholar | Crossref Dubbelaar, ML, Kracht, L, Eggen, BJL, Boddeke, EWGM. 2018. The kaleidoscope of microglial phenotypes. Front Immunol 9:1753.
Google Scholar | Crossref | Medline Dyer, CA, Hickey, WF, Geisert, EE. 1991. Myelin/oligodendrocyte-specific protein: a novel surface membrane protein that associates with microtubules. J Neurosci Res 28:607–13.
Google Scholar | Crossref | Medline Garbuzova-Davis, S . 2014. Blood-CNS barrier impairment in ALS patients versus an animal model. Front Cell Neurosci 8:21.
Google Scholar | Crossref | Medline | ISI Garbuzova-Davis, S, Hernandez-Ontiveros, DG, Rodrigues, MCO, Haller, E, Frisina-Deyo, A, Mirtyl, S others. 2012. Impaired blood-brain/spinal cord barrier in ALS patients. Brain Res 1469:114–28.
Google Scholar | Crossref | Medline Gibbons, HM, Smith, AM, Teoh, HH, Bergin, PM, Mee, EW, Faull, RLM others. 2011. Valproic acid induces microglial dysfunction, not apoptosis, in human glial cultures. Neurobiol Dis 41:96–103.
Google Scholar | Crossref | Medline Gomez-Nicola, D, Fransen, NL, Suzzi, S, Hugh Perry, V. 2013. Regulation of microglial proliferation during chronic neurodegeneration. J Neurosci 33:2481–93.
Google Scholar | Crossref | Medline Gosselin, D, Skola, D, Coufal, NG, Holtman, IR, Schlachetzki, JCM, Sajti, E others. 2017. An environment-dependent transcriptional network specifies human microglia identity. Science 356:1248–59.
Google Scholar | Crossref | Medline Grindberg, RV, Yee-Greenbaum, JL, Mcconnell, MJ, Novotny, M, Lin, X, Venepally, P others. 2013. RNA-sequencing from single nuclei. Proc Natl Acad Sci U S A 110:19802–7.
Google Scholar | Crossref | Medline Grubman, A, Chew, G, Ouyang, JF, Sun, G, Choo, XY, McLean, C others. 2019. A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation. Nat Neurosci 22:2087–97. doi:10.1038/s41593-019-0539-4
Google Scholar | Crossref | Medline Grundmann, S, Lindmayer, C, Hans, FP, Hoefer, I, Helbing, T, Pasterkamp, G others. 2013. FoxP1 stimulates angiogenesis by repressing the inhibitory guidance protein semaphorin 5B in endothelial cells. PLoS One 8:e70873.
Google Scholar | Crossref | Medline Guo, F, Maeda, Y, Ma, J, Xu, J, Horiuchi, M, Miers, L others. 2010. Pyramidal neurons are generated from oligodendroglial progenitor cells in adult piriform cortex. J Neurosci 30:12036–49.
Google Scholar | Crossref Gusel’nikova, VV, Korzhevskiy, DE. 2015. NeuN as a neuronal nuclear antigen and neuron differentiation marker. Acta Nat 7:42–7.
Google Scholar | Medline Haber, MA, Iranmahboob, A, Thomas, C, Liu, M, Najjar, A, Zagzag, D. 2015. ERG is a novel and reliable marker for endothelial cells in central nervous system tumors. Clin Neuropathol 34:117–27.
Google Scholar | Crossref | Medline Halliday, GM, Stevens, CH, Hons, B. 2011. Glia: initiators and progressors of pathology in Parkinson’s disease. Mov Disord 26:6–17.
Google Scholar | Crossref | Medline | ISI Hammond, SL, Safe, S, Tjalkens, RB. 2015. A novel synthetic activator of Nurr1 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitro. Neurosci Lett 607:83–9. doi:10.1016/j.neulet.2015.09.015
Google Scholar | Crossref | Medline Han, R, Pacifici, M, Iwamoto, M, Trojanowska, M. 2015. Endothelial ERG expression is required for embryogenesis and vascular integrity. Organogenesis 11:75–86.
Google Scholar | Crossref | Medline Hartfield, EM, Yamasaki-Mann, M, Ribeiro Fernandes, HJ, Vowles, J, James, WS, Cowley, SA others. 2014. Physiological characterisation of human iPS-derived dopaminergic neurons. PLoS One 9:e87388.
Google Scholar | Crossref | Medline He, L, Vanlandewijck, M, Raschperger, E, Andaloussi Maë, M, Jung, B, Lebouvier, T others. 2016. Analysis of the brain mural cell transcriptome. Sci Rep 6:35108. doi:10.1038/srep35108
Google Scholar | Crossref Hendricks, T, Francis, N, Fyodorov, D, Deneris, ES. 1999. The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes. J Neurosci 19:10348–56.
Google Scholar | Crossref | Medline Hevner, RF, Shi, L, Justice, N, Hsueh, YP, Sheng, M, Smiga, S others. 2001. Tbr1 regulates differentiation of the preplate and layer 6. Neuron 29:353–66.
Google Scholar | Crossref | Medline HPA . 2020a. Tissue expression of ERG-cerebral cortex. Human Protein Atlas. Available from: https://www.proteinatlas.org/ENSG00000157554-ERG/tissue/cerebral+cortex#img
Google Scholar HPA . 2020b. Tissue expression of Foxp1-staining in cerebral cortex. Human Protein Atlas. Available from: https://www.proteinatlas.org/ENSG00000114861-FOXP1/tissue/cerebral+cortex#img

留言 (0)

沒有登入
gif