Hepatocarcinogenesis

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CT and MR imaging diagnosis and staging of hepatocellular carcinoma: part I. development, growth, and spread: key pathologic and imaging aspects.

Radiology. 272: 635-654Narsinh K.H. Cui J. Papadatos D. et al.

Hepatocarcinogenesis and LI-RADS.

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Viral hepatocarcinogenesis.

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Review of genetic and epigenetic alterations in hepatocarcinogenesis.

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Large liver cell change in hepatitis B virus-related liver cirrhosis.

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Chromosomal abnormalities in liver cell dysplasia detected by comparative genomic hybridisation.

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Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis.

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Morphologic studies of the liver cell dysplasia.

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Clonality of nodular lesions in liver cirrhosis and chromosomal abnormalities in monoclonal nodules of altered hepatocytes.

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Emergence of malignant lesions within an adenomatous hyperplastic nodule in a cirrhotic liver. Observations in five cases.

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Terminology of nodular hepatocellular lesions.

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Ductular reaction is helpful in defining early stromal invasion, small hepatocellular carcinomas, and dysplastic nodules.

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Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia.

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Correlation between the blood supply and grade of malignancy of hepatocellular nodules associated with liver cirrhosis: evaluation by CT during intraarterial injection of contrast medium.

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Evidence supporting LI-RADS major features for CT- and MR imaging-based diagnosis of hepatocellular carcinoma: a systematic review.

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Performance of Gd-EOB-DTPA-enhanced MRI for the diagnosis of LI-RADS 4 category hepatocellular carcinoma nodules with different diameters.

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Progression and regression of fibrosis in viral hepatitis in the treatment era: the Beijing classification.

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Effect of threshold growth as a major feature on LI-RADS categorization.

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Prediction of the Ki-67 marker index in hepatocellular carcinoma based on CT radiomics features.

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Hepatocellular carcinoma with a pseudocapsule on gadolinium-enhanced MR images: correlation with histopathologic findings.

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LI-RADS major features: CT, MRI with extracellular agents, and MRI with hepatobiliary agents.

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The capsule appearance of hepatocellular carcinoma in gadoxetic acid-enhanced MR imaging: correlation with pathology and dynamic CT.

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LI-RADS version 2018 ancillary features at MRI.

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New OPTN/UNOS policy for liver transplant allocation: standardization of liver imaging, diagnosis, classification, and reporting of hepatocellular carcinoma.

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Pathology-MRI correlation of hepatocarcinogenesis: recent update.

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Corona enhancement and mosaic architecture for prognosis and selection between of liver resection versus transcatheter arterial chemoembolization in single hepatocellular carcinomas >5 cm without extrahepatic metastases: an imaging-based retrospective study.

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Mosaic pattern of hepatocellular carcinoma: histologic basis for a characteristic CT appearance.

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LI-RADS for MR imaging diagnosis of hepatocellular carcinoma: performance of major and ancillary features.

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Differentiation of hepatocellular carcinoma from other hepatic malignancies in patients at risk: diagnostic performance of the liver imaging reporting and data system version 2014.

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Imaging features of hepatocellular carcinoma compared to intrahepatic cholangiocarcinoma and combined tumor on MRI using liver imaging and data system (LI-RADS) version 2014.

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Enhancement patterns and signal-intensity characteristics of small hepatocellular carcinoma in cirrhosis: pathologic basis and diagnostic challenges.

Eur Radiol. 17: 2969-2982Choi J.Y. Lee J.M. Sirlin C.B.

CT and MR imaging diagnosis and staging of hepatocellular carcinoma: part II. Extracellular agents, hepatobiliary agents, and ancillary imaging features.

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Hypervascular focus in the nonhypervascular nodule (“nodule-in-nodule”) on dynamic computed tomography: imaging evidence of aggressive progression in hepatocellular carcinoma.

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cHCC-CCA: consensus terminology for primary liver carcinomas with both hepatocytic and cholangiocytic differentation.

Hepatology. 68: 113-126Gigante E. Ronot M. Bertin C. et al.

Combining imaging and tumour biopsy improves the diagnosis of combined hepatocellular-cholangiocarcinoma.

Liver Int. 39: 2386-2396Martin J. Sentis M. Zidan A. et al.

Fatty metamorphosis of hepatocellular carcinoma: detection with chemical shift gradient-echo MR imaging.

Radiology. 195: 125-130Balci N.C. Befeler A.S. Bieneman B.K. et al.

Fat containing HCC: findings on CT and MRI including serial contrast-enhanced imaging.

Acad Radiol. 16: 963-968Kutami R. Nakashima Y. Nakashima O. et al.

Pathomorphologic study on the mechanism of fatty change in small hepatocellular carcinoma of humans.

J Hepatol. 33: 282-289Asayama Y. Nishie A. Ishigami K. et al.

Fatty change in moderately and poorly differentiated hepatocellular carcinoma on MRI: a possible mechanism related to decreased arterial flow.

Clin Radiol. 71: 1277-1283Nakanuma Y. Hirata K. Terasaki S. et al.

Analytical histopathological diagnosis of small hepatocellular nodules in chronic liver disease.

Histol Histopathol. 13: 1077-1087Kitao A. Zen Y. Matsui O. et al.

Hepatocarcinogenesis: multistep changes of drainage vessels at CT during arterial portography and hepatic arteriography–radiologic-pathologic correlation.

Radiology. 252: 605-614

Diffusion-weighted MRI in the body: applications and challenges in oncology.

AJR Am J Roentgenol. 188: 1622-1635

Iron-negative foci in siderotic macroregenerative nodules in human cirrhotic liver. A marker of incipient neoplastic lesions.

Arch Pathol Lab Med. 113: 916-920

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