Bilevel non-invasive ventilation during exercise reduces dynamic hyperinflation and improves cycle endurance time in severe to very severe COPD.

Footnotes

Summary conflict of interest statements: The authors declare that they have no conflicts of interest in relation to this study (CJD, CM, TS, DL, USK, CMK, ARH, DJB, ARK, KK, JAA).

Funding information: No funding was received for this work.

Notation of prior abstract publication/presentation:

The effect of non-invasive ventilation (NIV) during exercise on inspiratory capacity (IC) and endurance time (Tlim) in patients with severe COPD

Clancy Dennis, Collette Menadue, Tessa Schneeberger, Daniela Leitl, Rainer Glöckl, Alison R Harmer, Ursula Schönheit-Kenn, David Barnes, Andreas Rembert Koczulla, Klaus Kenn, Jennifer A Alison

European Respiratory Journal Sep 2019, 54 (suppl 63) PA1232; https://doi.org/10.1183/13993003.congress-2019.PA1232

Clinical Trial Registration: Australian New Zealand Clinical Trials Registry, URL: http://www.anzctr.org.au, No: ACTRN12613000804785

In people with chronic obstructive pulmonary disease (COPD), expiratory flow limitation and increased lung compliance can cause resting lung hyperinflation, altering lung mechanics and increasing work of breathing1. During exercise, people with COPD may experience “dynamic” hyperinflation (DH), commonly defined as a decrease in inspiratory capacity (IC) of more than 150mL 2, which further increases work of breathing3 and exertional dyspnoea4. Exercise training is a key component of pulmonary rehabilitation for patients with COPD5. Training intensity is important with greater physiological training responses observed with higher compared to lower intensity exercise6. However, DH can significantly limit exercise intensity and duration in severe COPD and consequently interventions that reduce DH may improve exercise training responses4.

留言 (0)

沒有登入
gif