Antipsychotics in Children and Adolescents at Clinical High-risk of Psychosis

The prescription of antipsychotics in young children and adolescents is a delicate, complex and often divisive issue, where official guidelines and real-world prescriptive habits seldom correspond. Dinnissen M. Dietrich A. van der Molen J.H. et al. Prescribing antipsychotics in child and adolescent psychiatry: guideline adherence. Such discrepancy is even more radical and excruciating in those conditions with an established higher risk of imminent development of overt psychotic state (i.e. Clinical High Risk for Psychosis, CHR-P and the related diagnostic construct of DSM-5 attenuated psychosis syndrome (APS)) which fall below the severity threshold for a DSM-5 diagnosis of schizophrenia and other psychotic disorders.

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