Roles of vascular endothelial and smooth muscle cells in the vasculoprotective effect of insulin in a mouse model of restenosis

1. D’Ascenzo, F, Chieffo, A, Cerrato, E, et al. Incidence and management of restenosis after treatment of unprotected left main disease with second-generation drug-eluting stents (from Failure in Left Main Study With 2nd Generation Stents-Cardiogroup III Study). Am J Cardiol 2017; 119: 978–982.
Google Scholar | Crossref | Medline2. Breen, DM, Giacca, A. Effects of insulin on the vasculature. Curr Vasc Pharmacol 2011; 9: 321–332.
Google Scholar | Crossref | Medline3. Mori, Y, Chiang, S, Bendeck, MP, et al. Insulin decreases atherosclerotic plaque burden and increases plaque stability via nitric oxide synthase in apolipoprotein E-null mice. Am J Physiol Endocrinol Metab 2016; 311: E335–E345.
Google Scholar | Crossref | Medline4. Breen, DM, Chan, KK, Dhaliwall, JK, et al. Insulin increases reendothelialization and inhibits cell migration and neointimal growth after arterial injury. Arterioscler Thromb Vasc Biol 2009; 29: 1060–1066.
Google Scholar | Medline5. Breen, DM, Dhaliwall, JK, Chan, KK, et al. Insulin inhibits and oral sucrose increases neointimal growth after arterial injury in rats. J Vasc Res 2010; 47: 412–422.
Google Scholar | Crossref | Medline6. Guo, J, Breen, DM, Pereira, TJ, et al. The effect of insulin to decrease neointimal growth after arterial injury is endothelial nitric oxide synthase-dependent. Atherosclerosis 2015; 241: 111–120.
Google Scholar | Crossref | Medline7. Kim, T, Chan, KK, Dhaliwall, JK, et al. Anti-atherogenic effect of insulin in vivo. J Vasc Res 2005; 42: 455–462.
Google Scholar | Crossref | Medline8. Chiang, S, Breen, DM, Guo, J, et al. Local insulin application on the carotid artery inhibits neointima formation. Can J Physiol Pharmacol 2013; 91: 1086–1094.
Google Scholar | Crossref | Medline9. Costa, MA, Simon, DI. Molecular basis of restenosis and drug-eluting stents. Circulation 2005; 111: 2257–2273.
Google Scholar | Crossref | Medline | ISI10. Zeng, G, Nystrom, FH, Ravichandran, LV, et al. Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 2000; 101: 1539–1545.
Google Scholar | Crossref | Medline | ISI11. Wang, CC, Gurevich, I, Draznin, B. Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways. Diabetes 2003; 52: 2562–2569.
Google Scholar | Crossref | Medline | ISI12. Xi, XP, Graf, K, Goetze, S, et al. Inhibition of MAP kinase blocks insulin-mediated DNA synthesis and transcriptional activation of c-fos by Elk-1 in vascular smooth muscle cells. FEBS Lett 1997; 417: 283–286.
Google Scholar | Crossref | Medline | ISI13. Korhonen, H, Fisslthaler, B, Moers, A, et al. Anaphylactic shock depends on endothelial Gq/G11. J Exp Med 2009; 206: 411–420.
Google Scholar | Crossref | Medline14. Wirth, A, Benyó, Z, Lukasova, M, et al. G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension. Nat Med 2008; 14: 64–68.
Google Scholar | Crossref | Medline | ISI15. Brüning, JC, Michael, MD, Winnay, JN, et al. A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance. Mol Cell 1998; 2: 559–569.
Google Scholar | Crossref | Medline | ISI16. Rask-Madsen, C, Li, Q, Freund, B, et al. Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice. Cell Metab 2010; 11: 379–389.
Google Scholar | Crossref | Medline | ISI17. Kushima, H, Mori, Y, Koshibu, M, et al. The role of endothelial nitric oxide in the anti-restenotic effects of liraglutide in a mouse model of restenosis. Cardiovasc Diabetol 2017; 16: 122.
Google Scholar | Crossref | Medline18. Mori, Y, Kushima, H, Koshibu, M, et al. Glucose-dependent insulinotropic polypeptide suppresses peripheral arterial remodeling in male mice. Endocrinology 2018; 159: 2717–2732.
Google Scholar | Crossref | Medline19. Mori, Y, Shimizu, H, Kushima, H, et al. Nesfatin-1 suppresses peripheral arterial remodeling without elevating blood pressure in mice. Endocr Connect 2019; 8: 536–546.
Google Scholar | Crossref | Medline20. Mori, Y, Terasaki, M, Hiromura, M, et al. Luseogliflozin attenuates neointimal hyperplasia after wire injury in high-fat diet-fed mice via inhibition of perivascular adipose tissue remodeling. Cardiovasc Diabetol 2019; 18: 143.
Google Scholar | Crossref | Medline21. Johansson, GS, Arnqvist, HJ. Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells. Am J Physiol Endocrinol Metab 2006; 291: E1124–E1130.
Google Scholar | Crossref | Medline22. Sarkar, R, Gordon, D, Stanley, JC, et al. Dual cell cycle-specific mechanisms mediate the antimitogenic effects of nitric oxide in vascular smooth muscle cells. J Hypertens 1997; 15: 275–283.
Google Scholar | Crossref | Medline23. Metsärinne, K, Saijonmaa, O, Yki-Järvinen, H, et al. Insulin increases the release of endothelin in endothelial cell cultures in vitro but not in vivo. Metabolism 1994; 4: 878–882.
Google Scholar | Crossref24. Arai, F, Hirao, A, Ohmura, M, et al. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 2004; 118: 149–161.
Google Scholar | Crossref | Medline | ISI25. Baumgartl, J, Baudler, S, Scherner, M, et al. Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis. Cell Metab 2006; 3: 247–256.
Google Scholar | Crossref | Medline26. Han, S, Liang, CP, DeVries-Seimon, T, et al. Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions. Cell Metab 2006; 3: 257–266.
Google Scholar | Crossref | Medline27. Li, Q, Fu, J, Xia, Y, et al. Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistance and diabetes. Nat Commun 2019; 10: 4427.
Google Scholar | Crossref | Medline

留言 (0)

沒有登入
gif