1.
Lu, XY, Kim, CS, Frazer, A, Zhang, W. Leptin: a potential novel antidepressant. Proc Natl Acad Sci U S A. 2006;103:1593-1598.
Google Scholar |
Crossref |
Medline |
ISI2.
Lapin, IP, Oxenkrug, GF. Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect. Lancet. 1969;1:32-39.
Google Scholar |
Medline3.
Lapin, IP. Kynurenines as probable participants of depression. Pharmakopsychiatrie und Neuropsychopharmakologie. 1973;6:273-279.
Google Scholar |
Crossref |
Medline4.
Oxenkrug, G. Serotonin-kynurenine hypothesis of depression: historical overview and recent developments. Curr Drug Targets. 2013;14:514-521.
Google Scholar |
Crossref |
Medline |
ISI5.
Schwarcz, R, Bruno, JP, Muchowski, PJ, Wu, HQ. Kynurenines in the mammalian brain: when physiology meets pathology. Nat Rev Neurosci. 2012;13:465-477.
Google Scholar |
Crossref |
Medline |
ISI6.
Badawy, AA-B, Guillemin, G. The plasma [Kynurenine]/[Tryptophan] ratio and indoleamine 2,3-dioxygenase: time for appraisal. Int J Tryptophan Res. Published online August 21, 2019. doi:
10.1177/1178646919868978 Google Scholar |
SAGE Journals7.
Lord, GM. Leptin as a proinflammatory cytokine. Contrib Nephrol. 2006;151:151-164.
Google Scholar |
Crossref |
Medline8.
Mangge, H, Summers, KL, Meinitzer, A, et al. Obesity-related dysregulation of the tryptophan-kynurenine metabolism: role of age and parameters of the metabolic syndrome. Obesity (Silver Spring). 2014;22:195-201.
Google Scholar |
Crossref |
Medline |
ISI9.
Halaas, JL, Gajiwala, KS, Maffei, M, et al. Weight-reducing effects of the plasma protein encoded by the obese gene. Science. 1995;269:543-546.
Google Scholar |
Crossref |
Medline |
ISI10.
Guo, M, Huang, TY, Garza, JC, Chua, SC, Lu, XY. Selective deletion of leptin receptors in adult hippocampus induces depression-related behaviours. Int J Neuropsychopharmacol. 2013;16:857-867.
Google Scholar |
Crossref |
Medline |
ISI11.
Macht, VA, Vazquez, M, Petyak, CE, et al. Leptin resistance elicits depressive-like behaviors in rats. Brain Behav Immun. 2017;60:151-160.
Google Scholar |
Crossref |
Medline12.
Syk, M, Ellström, S, Mwinyi, J, et al. Plasma levels of leptin and adiponectin and depressive symptoms in young adults. Psychiatry Res. 2019;272:1-7.
Google Scholar |
Crossref |
Medline13.
Thomas, T, Stefanoni, D, Reisz, JA, et al. COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status. JCI Insight. 2020;5:pii:140327.
Google Scholar |
Crossref14.
Theofylaktopoulou, D, Midttun, O, Ulvik, A, et al. A community-based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study. Clin Exp Immunol. 2013;173:121-130.
Google Scholar |
Crossref |
Medline15.
Oxenkrug, G, Cornicelli, J, van der Hart, M, Roeser, J, Summergrad, P. Kynurenic acid, an aryl hydrocarbon receptor ligand, is elevated in serum of Zucker fatty rats. Integr Mol Med. 2016;3:761-763.
Google Scholar |
Medline16.
Strasser, B, Berger, K, Fuchs, D. Effects of a caloric restriction weight loss diet on tryptophan metabolism and inflammatory biomarkers in overweight adults. Eur J Nutr. 2015;54:101-107.
Google Scholar |
Crossref |
Medline |
ISI17.
Christensen, MHE, Fadnes, DJ, Røst, TH, et al. Inflammatory markers, the tryptophan-kynurenine pathway, and vitamin B status after bariatric surgery. PLoS One. 2018;13:e0192169.
Google Scholar |
Crossref |
Medline18.
Steiner, J, Fernandes, BS, Guest, PS, et al. Glucose homeostasis in major depression and schizophrenia: a comparison among drug-naïve first-episode patients. Eur Arch Psychiatry Clin Neurosci. 2019;269:373-377.
Google Scholar |
Crossref |
Medline19.
Marazziti, D, Rutigliano, G, Baroni, S, Landi, P, Dell’Osso, L. Metabolic syndrome and major depression. CNS Spectr. 2014;19:293-304.
Google Scholar |
Crossref |
Medline20.
Geisler, S, Mayersbach, P, Becker, K, Schennach, H, Fuchs, D, Gostner, JM. Serum tryptophan, kynurenine, phenylalanine, tyrosine and neopterin concentrations in 100 healthy blood donors. Pteridines. 2015;26:31-36.
Google Scholar |
Crossref21.
Steiner, J, Bernstein, HG, Guest, P, Summergrad, P, Oxenkrug, G. Plasma leptin correlates with anthranilic acid in schizophrenia but not in major depressive disorder. Eur Neuropsychopharmacol. 2020;41:167-168.
Google Scholar |
Crossref |
Medline22.
Ogyua, K, Kuboa, K, Nodaa, Y, et al. Kynurenine pathway in depression: a systematic review and meta-analysis. Neurosci Biobehav Rev. 2018;90:16-25.
Google Scholar |
Crossref |
Medline23.
Colle, R, Masson, P, Verstuyft, C, et al. Peripheral tryptophan, serotonin, kynurenine, and their metabolites in major depression: a case-control study. Psychiatry Clin Neurosci. 2020;74:112-117.
Google Scholar |
Crossref |
Medline24.
Pompili, M, Lionetto, L, Curto, M, et al. Tryptophan and kynurenine metabolites: are they related to depression? Neuropsychobiology. 2019;77:23-28.
Google Scholar |
Crossref |
Medline25.
Sakurai, M, Yamamoto, Y, Kanayama, N, et al. Serum metabolic profiles of the tryptophan-kynurenine pathway in the high risk subjects of major depressive disorder. Sci Rep. 2020;10:1961.
Google Scholar |
Crossref26.
Guloksuz, S, Arts, B, Walter, S, et al. The impact of electroconvulsive therapy on the tryptophan-kynurenine metabolic pathway. Brain Behav Immun. 2015;48:48-52.
Google Scholar |
Crossref |
Medline27.
Arnau-Soler, A, Macdonald-Dunlop, E, Adams, MJ, et al.; Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. 2019 Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland. Transl Psychiatry. 2019;9:14.
Google Scholar |
Crossref |
Medline28.
Sutphin, GL, Backer, G, Sheehan, S, et al.; the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Gene Expression Working Group. Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity. Aging Cell. 2017;16:672-682.
Google Scholar |
Crossref |
Medline29.
Lawson, EA, Miller, KK, Blum, JI, et al. Leptin levels are associated with decreased depressive symptoms in women across the weight spectrum, independent of body fat. Clin Endocrinol (Oxf). 2012;76:520-525.
Google Scholar |
Crossref |
Medline30.
Westling, S, Ahrén, B, Träskman-Bendz, L, Westrin, AJ. Low CSF leptin in female suicide attempters with major depression. Affect Disord. 2004;81:41-48.
Google Scholar |
Crossref |
Medline31.
Janelidze, S, Mattei, D, Westrin, Å, Träskman-Bendz, L, Brundin, L. Cytokine levels in the blood may distinguish suicide attempters from depressed patients. Brain Behav Immun. 2011;25:335-339.
Google Scholar |
Crossref |
Medline |
ISI32.
Morris, AA, Ahmed, Y, Stoyanova, N, et al. The association between depression and leptin is mediated by adiposity. Psychosom Med. 2012;74:483-488.
Google Scholar |
Crossref |
Medline33.
Castelo-Branco, C, Palacios, S, Vázquez, F, et al. Effects on serum lipid and leptin levels of three different doses of norethisterone continuously combined with a fixed dose of 17beta-estradiol for nasal administration in postmenopausal women: a controlled, double-blind study. Fertil Steril. 2007;88:383-389.
Google Scholar |
Crossref |
Medline34.
Fungfuang, W, Terada, M, Komatsu, N, Moon, C, Saito, TR. Effects of estrogen on food intake, serum leptin levels and leptin mRNA expression in adipose tissue of female rats. Lab Anim Res. 2013;29:168-173.
Google Scholar |
Crossref |
Medline35.
Diano, S, Kalra, SP, Sakamoto, H, Horvath, TL. Leptin receptors in estrogen receptor-containing neurons of the female rat hypothalamus. Brain Res. 1998;812:256-259.
Google Scholar |
Crossref |
Medline36.
Merk, D, Gabler, M, Gomez, RC, et al. Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR). Bioorg Med Chem. 2014;22:2447-2460.
Google Scholar |
Crossref |
Medline37.
Forman, BM, Goode, E, Chen, J, et al. Identification of a nuclear receptor that is activated by farnesol metabolites. Cell. 1995;81:687-693.
Google Scholar |
Crossref |
Medline |
ISI38.
Xin, XM, Zhong, MX, Yang, GL, Peng, Y, Zhang, YL, Zhu, W. GW4064, a farnesoid X receptor agonist, upregulates adipokine expression in preadipocytes and HepG2 cells. World J Gastroenterol. 2014;20:15727-15735.
Google Scholar |
Crossref |
Medline39.
Chan, SY, Matthews, E, Burnet, PWJ. On or off?: modulating the N-methyl-D-aspartate receptor in major depression. Front Mol Neurosci. 2017;9:169.
Google Scholar |
Crossref |
Medline40.
Lennerz, B, Vafai, SB, Delaney, NF, et al. Effects of sodium benzoate, a widely used food preservative, on glucose homeostasis and metabolic profiles in humans. Mol Genet Metab. 2015;114:73-79.
Google Scholar |
Crossref |
Medline41.
Balderas-Hernández, VE, Treviño-Quintanilla, LG, Hernández-Chávez, G, Martinez, A, Bolívar, F, Gosset, G. Catechol biosynthesis from glucose in Escherichia coli anthranilate-overproducer strains by heterologous expression of anthranilate 1,2-dioxygenase from Pseudomonas aeruginosa PAO1. Microb Cell Fact. 2014;13:136.
Google Scholar |
Crossref |
Medline
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