Forest of darkness: imaging with OCT-angiography as a useful tool to study corneal vascularization

En-face imaging was performed using the swept source anterior segment OCT angiography (AS-OCTA) system (Plex Elite 9000, Carl Zeiss Meditec, California, USA) equipped with a 10-diopter optical adapter lens for anterior segment applications. Scan patterns corresponded to 6 × 6 mm in the cornea.

Multiple tufts of thick vessels originating from limbus with several bifurcations extending over central cornea were documented (Fig. 1b). The patient was started on topical loteprednol etabonate 1% eye drop twice a day and Oral acyclovir 400 mg twice a day. Four months after initiation of therapy, there was marked reduction in the blood flow, calibre, and density of corneal vessels on slit lamp examination (Fig. 1c) and en-face AS-OCTA (Fig. 1d). The UDVA also improved to 20/30 in the affected eye. We conclude that AS-OCTA serves as an adjunctive investigation for delineation and in monitoring treatment response of patients presenting with corneal vascularization [1, 2].

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