Neutrophil-to-Lymphocyte Ratio Differentiates Infections from Sterile Inflammation in First Week of Acute Pancreatitis

Kylänpää L, Rakonczay Z, O’Reilly DA. The clinical course of acute pancreatitis and the inflammatory mediators that drive it. Int J Inflamm. 2012;2012:360685. https://doi.org/10.1155/2012/360685.

Article  CAS  Google Scholar 

Chakraborty RK, Burns B. Systemic inflammatory response syndrome. In: StatPearls. StatPearls Publishing; 2024. Accessed May 6, 2024. http://www.ncbi.nlm.nih.gov/books/NBK547669/

Besselink MG, van Santvoort HC, Boermeester MA et al. Timing and impact of infections in acute pancreatitis. Br J Surg. 2009;96:267–273. https://doi.org/10.1002/bjs.6447.

Article  CAS  PubMed  Google Scholar 

Janka T, Tornai D, Papp M, Vitális Z. The value of neutrophil-to-lymphocyte ratio to identify bacterial infection and predict short-term mortality in patients with acutely decompensated cirrhosis. Diagnostics. 2023;13:2954. https://doi.org/10.3390/diagnostics13182954.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Procalcitonin as a biomarker of infectious diseases-PubMed. Accessed March 31, 2024. https://pubmed.ncbi.nlm.nih.gov/23682219/

Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–383. https://doi.org/10.1016/0021-9681(87)90171-8.

Article  CAS  PubMed  Google Scholar 

Banks PA, Bollen TL, Dervenis C et al. Classification of acute pancreatitis–2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62:102–111. https://doi.org/10.1136/gutjnl-2012-302779.

Article  PubMed  Google Scholar 

Wu BU, Johannes RS, Sun X, Tabak Y, Conwell DL, Banks PA. The early prediction of mortality in acute pancreatitis: a large population-based study. Gut. 2008;57:1698–1703. https://doi.org/10.1136/gut.2008.152702.

Article  CAS  PubMed  Google Scholar 

Forsmark CE, Swaroop Vege S, Wilcox CM. Acute pancreatitis. N Engl J Med. 2016;375:1972–1981. https://doi.org/10.1056/NEJMra1505202.

Article  CAS  PubMed  Google Scholar 

Zerem E. Treatment of severe acute pancreatitis and its complications. World J Gastroenterol WJG. 2014;20:13879–13892. https://doi.org/10.3748/wjg.v20.i38.13879.

Article  PubMed  Google Scholar 

Rao C, Bhasin DK, Rana SS, Gupta R, Gautam V, Singh K. Implications of culture positivity in acute pancreatitis: does the source matter? J Gastroenterol Hepatol. 2013;28:887–892. https://doi.org/10.1111/jgh.12161.

Article  PubMed  Google Scholar 

Jain S, Mahapatra SJ, Gupta S, Shalimar, Garg PK. Infected pancreatic necrosis due to multidrug-resistant organisms and persistent organ failure predict mortality in acute pancreatitis. Clin Transl Gastroenterol. 2018;9:190. https://doi.org/10.1038/s41424-018-0056-x.

Article  PubMed  PubMed Central  Google Scholar 

van Baal MC, Bollen TL, Bakker OJ et al. The role of routine fine-needle aspiration in the diagnosis of infected necrotizing pancreatitis. Surgery. 2014;155:442–448. https://doi.org/10.1016/j.surg.2013.10.001.

Article  PubMed  Google Scholar 

CRE Technical Information, CRE, HAI, CDC. February 22, 2021. Accessed March 3, 2024. https://www.cdc.gov/hai/organisms/cre/technical-info.html

Ghafourian S, Sadeghifard N, Soheili S, Sekawi Z. Extended spectrum beta-lactamases: definition, classification and epidemiology. Curr Issues Mol Biol. 2015;17:11–22. https://doi.org/10.21775/cimb.017.011.

Article  PubMed  Google Scholar 

Magiorakos AP, Srinivasan A, Carey RB et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18:268–281. https://doi.org/10.1111/j.1469-0691.2011.03570.x.

Article  CAS  PubMed  Google Scholar 

Azab B, Jaglall N, Atallah JP et al. Neutrophil-lymphocyte ratio as a predictor of adverse outcomes of acute pancreatitis. Pancreatology. 2011;11:445–452. https://doi.org/10.1159/000331494.

Article  PubMed  Google Scholar 

Jeon TJ, Park JY. Clinical significance of the neutrophil-lymphocyte ratio as an early predictive marker for adverse outcomes in patients with acute pancreatitis. World J Gastroenterol. 2017;23:3883–3889. https://doi.org/10.3748/wjg.v23.i21.3883.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Halaseh SA, Kostalas M, Kopec C et al. Neutrophil-to-lymphocyte ratio as an early predictor of complication and mortality outcomes in individuals with acute pancreatitis at a UK district general hospital: a retrospective analysis. Cureus. 2022. https://doi.org/10.7759/cureus.29782.

Article  PubMed  PubMed Central  Google Scholar 

Kokulu K, Günaydın YK, Akıllı NB et al. Relationship between the neutrophil-to-lymphocyte ratio in acute pancreatitis and the severity and systemic complications of the disease. Turk J Gastroenterol. 2018;29:684–691. https://doi.org/10.5152/tjg.2018.17563.

Article  PubMed  PubMed Central  Google Scholar 

Bhanou NMS, Balachandran G, Jain NB. Neutrophil to lymphocyte ratio (NLR) in acute pancreatitis as an early predictor of severity and outcome. Int Surg J. 2018;5:3545–3548. https://doi.org/10.18203/2349-2902.isj20184619.

Article  Google Scholar 

Vemparala SV, Bhat AGK, Bhat NK, Hande MH. Neutrophil to lymphocyte ratio as an early predictive marker for adverse outcomes in patients with acute pancreatitis. J Clin Diagn Res. 2021. https://doi.org/10.7860/JCDR/2021/51705.15729.

Article  Google Scholar 

Kong W, He Y, Bao H, Zhang W, Wang X. Diagnostic value of neutrophil-lymphocyte ratio for predicting the severity of acute pancreatitis: a meta-analysis. Dis Markers. 2020;2020:e9731854. https://doi.org/10.1155/2020/9731854.

Article  Google Scholar 

Jain V, Nath P, Patro S. Evaluation of diagnostic accuracy of inflammation markers [Neutrophil-Lymphocyte Ratio (NLR), Red cell Distribution Width (RDW), Prognostic Nutritional Index (PNI) and Lymphocyte Monocyte Ratio (LMR)] for outcomes in patients with acute pancreatitis. J Assoc Phys India. 2022;70:11–12.

CAS  Google Scholar 

Johnson MM, Gicking JC, Keys DA. Evaluation of red blood cell distribution width, neutrophil-to-lymphocyte ratio, and other hematologic parameters in canine acute pancreatitis. J Vet Emerg Crit Care. 2023;33:587–597. https://doi.org/10.1111/vec.13325.

Article  Google Scholar 

Vélez-Páez JL, Tercero-Martínez W, Jiménez-Alulima G et al. Neutrophil-to-lymphocyte ratio and mean platelet volume in the diagnosis of bacterial infections in COVID-19 patients. A preliminary analysis from Ecuador. Infez Med. 2021;29:530–537. https://doi.org/10.53854/liim-2904-5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Beberashvili I, Omar MA, Nizri E, Stav K, Efrati S. Combined use of CRP with neutrophil-to-lymphocyte ratio in differentiating between infectious and noninfectious inflammation in hemodialysis patients. Sci Rep. 2023;13:5463. https://doi.org/10.1038/s41598-023-32270-8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Marstrand-Joergensen MR, Bertilsson S, Kalaitzakis E. Extrapancreatic infections are common in acute pancreatitis and they are related to organ failure: a population-based study. Eur J Gastroenterol Hepatol. 2020;32:1293. https://doi.org/10.1097/MEG.0000000000001847.

Article  CAS  PubMed  Google Scholar 

Ni T, Wen Y, Zhao B et al. Characteristics and risk factors for extrapancreatic infection in patients with moderate or severe acute pancreatitis. Heliyon. 2023;9:e13131. https://doi.org/10.1016/j.heliyon.2023.e13131.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bohidar NP, Garg PK, Khanna S, Tandon RK. Incidence, etiology, and impact of fever in patients with acute pancreatitis. Pancreatol Off J Int Assoc Pancreatol IAP Al. 2003;3:9–13. https://doi.org/10.1159/000069146.

Article  CAS  Google Scholar 

Moka P, Goswami P, Kapil A, Xess I, Sreenivas V, Saraya A. Impact of antibiotic-resistant bacterial and fungal infections in outcome of acute pancreatitis. Pancreas. 2018;47:489–494. https://doi.org/10.1097/MPA.0000000000001019.

Article  PubMed  Google Scholar 

Wu D, Jia Y, Cai W et al. Impact of multiple drug-resistant Gram-negative bacterial bacteraemia on infected pancreatic necrosis patients. Front Cell Infect Microbiol. 2022. https://doi.org/10.3389/fcimb.2022.1044188.

Article 

留言 (0)

沒有登入
gif