Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012;481:463–8.
Article PubMed PubMed Central Google Scholar
Torabi A, Reisi J, Kargarfard M, Mansourian M. Differences in the Impact of Various Types of Exercise on Irisin Levels: A Systematic Review and Meta-Analysis. Int J Prev Med. 2024;15:11.
Article PubMed PubMed Central Google Scholar
Varela-Rodríguez BM, Pena-Bello L, Juiz-Valiña P, Vidal-Bretal B, Cordido F, Sangiao-Alvarellos S. FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle. Sci Rep. 2016;6:29898.
Article PubMed PubMed Central Google Scholar
Aladag T, Mogulkoc R, Baltaci AK. Irisin and Energy Metabolism and the Role of Irisin on Metabolic Syndrome. Mini Rev Med Chem. 2023;23:1942–58.
Article CAS PubMed Google Scholar
Hu X, Wang Z, Wang W, Cui P, Kong C, Chen X, et al. Irisin as an agent for protecting against osteoporosis: A review of the current mechanisms and pathways. J Adv Res. 2024;62:175–86.
Zhang Y, Li R, Meng Y, Li S, Donelan W, Zhao Y, et al. Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling. Diabetes. 2014;63:514–25.
Article CAS PubMed Google Scholar
Li Q, Tan Y, Chen S, Xiao X, Zhang M, Wu Q, et al. Irisin alleviates LPS-induced liver injury and inflammation through inhibition of NLRP3 inflammasome and NF-κB signaling. J Recept Signal Transduct Res. 2021;41:294–303.
Article CAS PubMed Google Scholar
Park MJ, Kim DI, Choi JH, Heo YR, Park SH. New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro. Cell Signal. 2015;27:1831–9.
Article CAS PubMed Google Scholar
Ahmad IH, Mohamed Mostafa ER, Mohammed SA, Shipl W, Soliman AA, Said M. Correlations between serum testosterone and irisin levels in a sample of Egyptian men with metabolic syndrome; (case-control study). Arch Physiol Biochem. 2023;129:180–5.
Article CAS PubMed Google Scholar
Assyov Y, Gateva A, Karamfilova V, Gatev T, Nedeva I, Velikova T, et al. Impact of testosterone treatment on circulating irisin in men with late-onset hypogonadism and metabolic syndrome. Aging Male. 2021;23:1381–7.
Kamenov Z, Assyov Y, Angelova P, Gateva A, Tsakova A. Irisin and Testosterone in Men with Metabolic Syndrome. Horm Metab Res. 2017;49:755–9.
Article CAS PubMed Google Scholar
Barbonetti A, Castellini C, Francavilla S, Francavilla F, D’Andrea S. Metabolic syndrome in spinal cord injury: Impact on health. In: Rajendram R, Preedy VR, Martin RCR, editors. The Neuroscience of spinal cord injury: Cellular, molecular, physiological, and behavioral aspects of spinal cord injury. ELSEVIER, Acedemic press, London, England; 2022. pp 377–88.
Gorgey AS, Dolbow DR, Dolbow JD, Khalil RK, Castillo C, Gater DR. Effects of spinal cord injury on body composition and metabolic profile - Part I. J Spinal Cord Med. 2014;37:693–702.
Article PubMed PubMed Central Google Scholar
Barbonetti A, Caterina Vassallo MR, Cotugno M, Felzani G, Francavilla S, Francavilla F. Low testosterone and non-alcoholic fatty liver disease: Evidence for their independent association in men with chronic spinal cord injury. J Spinal Cord Med. 2016;39:443–9.
Article PubMed PubMed Central Google Scholar
Farkas GJ, Gater DR. Neurogenic obesity and systemic inflammation following spinal cord injury: A review. J Spinal Cord Med. 2018;41:378–87.
Goldsmith JA, Lai RE, Garten RS, Chen Q, Lesnefsky EJ, Perera RA, et al. Visceral Adiposity, Inflammation, and Testosterone Predict Skeletal Muscle Mitochondrial Mass and Activity in Chronic Spinal Cord Injury. Front Physiol. 2022;13:809845.
Article PubMed PubMed Central Google Scholar
Bauman WA, La Fountaine MF, Spungen AM. Age-related prevalence of low testosterone in men with spinal cord injury. J Spinal Cord Med. 2014;37:32–39.
Article PubMed PubMed Central Google Scholar
Barbonetti A, Vassallo MR, Felzani G, Francavilla S, Francavilla F. Association between 25(OH)-vitamin D and testosterone levels: Evidence from men with chronic spinal cord injury. J Spinal Cord Med. 2016;39:246–52.
Article PubMed PubMed Central Google Scholar
Barbonetti A, Vassallo MR, Pacca F, Cavallo F, Costanzo M, Felzani G, et al. Correlates of low testosterone in men with chronic spinal cord injury. Andrology. 2014;2:721–8.
Article CAS PubMed Google Scholar
Abilmona SM, Sumrell RM, Gill RS, Adler RA, Gorgey AS. Serum testosterone levels may influence body composition and cardiometabolic health in men with spinal cord injury. Spinal Cord. 2019;57:229–39.
Harman SM, Metter EJ, Tobin JD, Pearson J, Blackman MR. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltim Longitud Study Aging J Clin Endocrinol Metab. 2001;86:724–31.
Maynard FM Jr, Bracken MB, Creasey G, Ditunno JF Jr, Donovan WH, Ducker TB, et al. International Standards for Neurological and Functional Classification of Spinal Cord Injury. American Spinal Injury Association. Spinal Cord. 1997;35:266–74.
Ginis KAM, Phang SH, Latimer AE, Arbour-Nicitopoulos KP. Reliability and validity tests of the leisure time physical activity questionnaire for people with spinal cord injury. Arch Phys Med Rehabil. 2012;93:677–82.
Barbonetti A, Sperandio A, Micillo A, D’Andrea S, Pacca F, Felzani G, et al. Independent Association of Vitamin D with Physical Function in People with Chronic Spinal Cord Injury. Arch Phys Med Rehabil. 2016;97:726–32.
Wu FC, Tajar A, Beynon JM, Pye SR, Silman AJ, Finn JD, et al. EMAS Group. Identification of late-onset hypogonadism in middle-aged and elderly men. N Engl J Med. 2010;363:123–35.
Article CAS PubMed Google Scholar
Jedrychowski MP, Wrann CD, Paulo JA, Gerber KK, Szpyt J, Robinson MM, et al. Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry. Cell Metab. 2015;22:734–40.
Article CAS PubMed PubMed Central Google Scholar
Yang S, Xiao F, Pan L, Zhang H, Ma Z, Liu S, et al. Association of serum irisin and body composition with chronic kidney disease in obese Chinese adults: a cross-sectional study. BMC Nephrol. 2015;16:16.
Article PubMed PubMed Central Google Scholar
Moreno-Navarrete JM, Ortega F, Serrano M, Guerra E, Pardo G, Tinahones F, et al. Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance. J Clin Endocrinol Metab. 2013;98:E769–78.
Article CAS PubMed Google Scholar
Isidori AM, Caprio M, Strollo F, Moretti C, Frajese G, Isidori A, et al. Leptin and androgens in male obesity: evidence for leptin contribution to reduced androgen levels. J Clin Endocrinol Metab. 1999;84:3673–80.
Saez JM. Leydig cells: endocrine, paracrine, and autocrine regulation. Endocr Rev. 1994;15:574–626.
Article CAS PubMed Google Scholar
Kalra PS, Edwards TG, Xu B, Jain M, Kalra SP. The anti-gonadotropic effects of cytokines: the role of neuropeptides. Domest Anim Endocrinol. 1998;15:321–32.
Article CAS PubMed Google Scholar
Assyov Y, Gateva A, Karamfilova V, Gatev T, Nedeva I, Velikova T, et al. Impact of testosterone treatment on circulating irisin in men with late-onset hypogonadism and metabolic syndrome. Aging Male. 2020;23:1381–7.
Huhtaniemi IT, Tajar A, Lee DM, O’Neill TW, Finn JD, Bartfai G, et al. EMAS Group. Comparison of serum testosterone and estradiol measurements in 3174 European men using platform immunoassay and mass spectrometry; relevance for the diagnostics in aging men. Eur J Endocrinol. 2012;166:983–91.
留言 (0)