Front. Cardiovasc. Med.

Sec. Cardiovascular Imaging

Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1501004

Provisionally accepted

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The left atrial stiffness index (LASI) holds significance in the atrioventricular coupling function and heart failure progression. To assess left atrial function and evaluate the relationship between LASI and exercise capacity in hypertensionrelated heart failure with preserved ejection fraction (HT-HFpEF). Methods: The study involved 62 healthy subjects and 163 patients with HT (112 patients in simple HT group and 51 patients in HT-HFpEF group). Each patient performed exercise stress test and standard ultrasonic images were evaluated. A comprehensive evaluation of atrioventricular function, along with investigation into the correlation between these functional parameters and exercise capacity. And further to investigate the feasibility of predicting exercise intolerance using threedimensional derived left atrial strain index (LASI) (E/e'/LASr and E/e'/LASr-c). Results: Compared to healthy subjects, HT group demonstrated the elevation in left atrial volume accompanied by decrease in strain value (P

Keywords: three-dimensional speckle tracking, Left atrial, Hypertension, stiffness, heart faliure

Received: 24 Sep 2024; Accepted: 03 Dec 2024.

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