Funding

No external funding was used in the preparation of this manuscript.

Conflict of interest

Chiara Ciccarese has received speaker honoraria from Astellas, BMS, EISAI, IPSEN, Janssen, MSD, Novartis, Pfizer, and Sanofi. Matteo Bauckneht has received speaker honoraria from Novartis and GE Healthcare. Giampaolo Tortora is an advisory board member for BMS and Novartis. Luca Zagaria has received speaker honoraria from Novartis. Orazio Caffo has received speaker honoraria from Astellas, Astra Zeneca, Bayer, Janssen, Ipsen, MSD, Novartis, Pfizer, and Recordati. Roberto Iacovelli is an advisory board member for Astellas, BMS, EISAI, IPSEN, Janssen, MSD, Novartis, Pfizer, and Sanofi and a consultant for Astellas, EISAI, MSD, and Pfizer. Giuseppe Fornarini, Viria Beccia, Francesco Lanfranchi, Germano Perotti, Giada Pinterpe, Fortuna Migliaccio, Lucia Leccisotti, Gianmario Sambuceti, and Alessandro Giordano declare that they have no conflicts of interest that might be relevant to the contents of this manuscript.

Ethics approval

Not applicable.

Consent to participate

Not applicable.

Consent for publication

Not applicable.

Availability of data and material

All data generated or analyzed during this study are included in this published article and its supplementary information files.

Code availability

Not applicable.

Authors' contributions

Conceptualization: C.C., M.B., and R.I. Data curation: L.Z., G.F., V.B., F.L., G.P., G.P., F.M., G.T., L.L., G.S., A.G., and O.C. Formal analysis: C.C., M.B., and R.I. Investigation: C.C., and M.B. Methodology: all authors. Software: C.C. and R.I. Writing - original draft: C.C., M.B., and R.I. Writing - review & editing: all authors.