Gasdermin D unlocks metabolic pathways to enhance tissue regeneration

Chi Z, Chen S, Yang D, Cui W, Lu Y, Wang Z, et al. Gasdermin D-mediated metabolic crosstalk promotes tissue repair. Nature. 2024;634:1168–77.

Article  CAS  PubMed  Google Scholar 

Wei X, Xie F, Zhou X, Wu Y, Yan H, Liu T, et al. Role of pyroptosis in inflammation and cancer. Cell Mol Immunol. 2022;19:971–92.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cai Q, Shubhra QTH. Gasdermin D triggers cardiolipin-driven mitochondrial damage and pyroptosis. Trends Immunol. 2024;45:75–7.

Article  CAS  PubMed  Google Scholar 

Bertheloot D, Latz E, Franklin BS. Necroptosis, pyroptosis and apoptosis: an intricate game of cell death. Cell Mol Immunol. 2021;18:1106–21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kim HS, Moon S-J, Lee SE, Hwang GW, Yoo HJ, Song JW. The arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis. Exp Mol Med. 2021;53:864–74.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Relaix F, Bencze M, Borok MJ, Der Vartanian A, Gattazzo F, Mademtzoglou D, et al. Perspectives on skeletal muscle stem cells. Nat Commun. 2021;12:692.

Article  CAS  PubMed  PubMed Central  Google Scholar 

de Morree A, Klein JDD, Gan Q, Farup J, Urtasun A, Kanugovi A, et al. Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function. Science. 2019;366:734–8.

Article  PubMed  PubMed Central  Google Scholar 

Gioftsidi S, Relaix F, Mourikis P. The Notch signaling network in muscle stem cells during development, homeostasis, and disease. Skelet Muscle. 2022;12:9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Evavold CL, Hafner-Bratkovič I, Devant P, D’Andrea JM, Ngwa EM, Boršić E, et al. Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway. Cell. 2021;184:4495–511.e19.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu Y, Guo K, Ding M, Zhang B, Xiao N, Tang Z, et al. Engineered magnetic polymer nanoparticles can ameliorate breast cancer treatment inducing pyroptosis–starvation along with chemotherapy. ACS Appl Mater Interfaces. 2022;14:42541–57.

Article  CAS  PubMed  Google Scholar 

留言 (0)

沒有登入
gif