Riely GJ, Wood DE, Ettinger DS, Aisner DL, Akerley W, Bauman JR, Bharat A, Bruno DS, Chang JY, Chirieac LR, DeCamp M, Desai AP, Dilling TJ, Dowell J, Durm GA, Gettinger S, Grotz TE, Gubens MA, Juloori A, Lackner RP, Lanuti M, Lin J, Loo BW, Lovly CM, Maldonado F, Massarelli E, Morgensztern D, Mullikin TC, Ng T, Owen D, Owen DH, Patel SP, Patil T, Polanco PM, Riess J, Shapiro TA, Singh AP, Stevenson J, Tam A, Tanvetyanon T, Yanagawa J, Yang SC, Yau E, Gregory KM, Hang L. Non-small cell lung cancer, version 4 2024. J Natl Compr Canc Netw. 2024;22(4):249–74. https://doi.org/10.6004/jnccn.2204.0023. PMID: 38754467.

Article  CAS  PubMed  Google Scholar 

Zheng RS, Chen R, Han BF, Wang SM, Li L, Sun KX, Zeng HM, Wei WW, He J. Cancer incidence and mortality in China, 2022. Zhonghua Zhong Liu Za Zhi. 2024;46(3):221–31. https://doi.org/10.3760/cma.j.cn112152-20240119-00035. Chinese. PMID: 38468501.

Article  CAS  PubMed  Google Scholar 

Kuang M, Shen X, Yuan C, Hu H, Zhang Y, Pan Y, Cheng C, Zheng D, Cheng L, Zhao Y, Tao X, Li Y, Chen H, Sun Y. Clinical significance of complex glandular patterns in lung adenocarcinoma: clinicopathologic and molecular study in a large series of cases. Am J Clin Pathol. 2018;150(1):65–73. https://doi.org/10.1093/ajcp/aqy032. PMID: 29746612; PMCID: PMC5978020.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JHM, Beasley MB, Chirieac LR, Dacic S, Duhig E, Flieder DB, Geisinger K, Hirsch FR, Ishikawa Y, Kerr KM, Noguchi M, Pelosi G, Powell CA, Tsao MS, Wistuba I, WHO Panel. The 2015 World Health Organization classification of lung tumors: impact of genetic, clinical and radiologic advances since the 2004 classification. J Thorac Oncol. 2015;10(9):1243–60. https://doi.org/10.1097/JTO.0000000000000630. PMID: 26291008.

Article  Google Scholar 

Moreira AL, Ocampo PSS, Xia Y, Zhong H, Russell PA, Minami Y, Cooper WA, Yoshida A, Bubendorf L, Papotti M, Pelosi G, Lopez-Rios F, Kunitoki K, Ferrari-Light D, Sholl LM, Beasley MB, Borczuk A, Botling J, Brambilla E, Chen G, Chou TY, Chung JH, Dacic S, Jain D, Hirsch FR, Hwang D, Lantuejoul S, Lin D, Longshore JW, Motoi N, Noguchi M, Poleri C, Rekhtman N, Tsao MS, Thunnissen E, Travis WD, Yatabe Y, Roden AC, Daigneault JB, Wistuba II, Kerr KM, Pass H, Nicholson AG, Mino-Kenudson M. A grading system for invasive pulmonary adenocarcinoma: a proposal from the International Association for the Study of Lung Cancer Pathology Committee. J Thorac Oncol. 2020;15(10):1599–610. https://doi.org/10.1016/j.jtho.2020.06.001. Epub 2020 Jun 17. PMID: 32562873; PMCID: PMC8362286.

Article  PubMed  PubMed Central  Google Scholar 

Nicholson AG, Tsao MS, Beasley MB, Borczuk AC, Brambilla E, Cooper WA, Dacic S, Jain D, Kerr KM, Lantuejoul S, Noguchi M, Papotti M, Rekhtman N, Scagliotti G, van Schil P, Sholl L, Yatabe Y, Yoshida A, Travis WD. The 2021 WHO classification of lung tumors: impact of advances since 2015. J Thorac Oncol. 2022;17(3):362–87.

Article  PubMed  Google Scholar 

Kadota K, Kushida Y, Kagawa S, Ishikawa R, Ibuki E, Inoue K, Go T, Yokomise H, Ishii T, Kadowaki N, Haba R. Cribriform subtype is an independent predictor of recurrence and survival after adjustment for the eighth edition of TNM staging system in patients with resected lung adenocarcinoma. J Thorac Oncol. 2019;14(2):245–54. https://doi.org/10.1016/j.jtho.2018.09.028. Epub 2018 Oct 15. PMID: 30336325.

Article  PubMed  Google Scholar 

Mäkinen JM, Laitakari K, Johnson S, Mäkitaro R, Bloigu R, Pääkkö P, Lappi-Blanco E, Kaarteenaho R. Histological features of malignancy correlate with growth patterns and patient outcome in lung adenocarcinoma. Histopathology. 2017;71(3):425–36. https://doi.org/10.1111/his.13236. Epub 2017 Jun 16. PMID: 28401582.

Article  PubMed  Google Scholar 

Warth A, Muley T, Kossakowski C, Stenzinger A, Schirmacher P, Dienemann H, Weichert W. Prognostic impact and clinicopathological correlations of the cribriform pattern in pulmonary adenocarcinoma. J Thorac Oncol. 2015;10(4):638–44. https://doi.org/10.1097/JTO.0000000000000490. PMID: 25634008.

Article  CAS  PubMed  Google Scholar 

Chen L, Zhang Z. The self-distillation trained multitask dense-attention network for diagnosing lung cancers based on CT scans. Med Phys. 2024;51(3):1738–53. https://doi.org/10.1002/mp.16736. Epub 2023 Sep 16. PMID: 37715993.

Article  CAS  PubMed  Google Scholar 

Lin G, Li H, Kuang J, Tang K, Guo Y, Han A, Xie C. Acinar-predominant pattern correlates with poorer prognosis in invasive mucinous adenocarcinoma of the lung. Am J Clin Pathol. 2018;149(5):373–8. https://doi.org/10.1093/ajcp/aqx170. PMID: 29538611.

Article  PubMed  Google Scholar 

Sica G, Yoshizawa A, Sima CS, Azzoli CG, Downey RJ, Rusch VW, Travis WD, Moreira AL. A grading system of lung adenocarcinomas based on histologic pattern is predictive of disease recurrence in stage I tumors. Am J Surg Pathol. 2010;34(8):1155–62. https://doi.org/10.1097/PAS.0b013e3181e4ee32. PMID: 20551825.

Article  PubMed  Google Scholar 

Zhang Y, Wang R, Cai D, Li Y, Pan Y, Hu H, Wang L, Li H, Ye T, Luo X, Zhang Y, Li B, Shen L, Sun Y, Chen H. A comprehensive investigation of molecular features and prognosis of lung adenocarcinoma with micropapillary component. J Thorac Oncol. 2014;9(12):1772–8. https://doi.org/10.1097/JTO.0000000000000341. PMID: 25226429.

Article  CAS  PubMed  Google Scholar 

Jeon HW, Kim YD, Sim SB, Moon MH. Significant difference in recurrence according to the proportion of high grade patterns in stage IA lung adenocarcinoma. Thorac Cancer. 2021;12(13):1952–8. https://doi.org/10.1111/1759-7714.13984. Epub 2021 May 25. PMID: 34037324; PMCID: PMC8258359.

Article  PubMed  PubMed Central  Google Scholar 

Mikubo M, Tamagawa S, Kondo Y, Hayashi S, Sonoda D, Naito M, Shiomi K, Ichinoe M, Satoh Y. Micropapillary and solid components as high-grade patterns in IASLC grading system of lung adenocarcinoma: clinical implications and management. Lung Cancer. 2024;187:107445. https://doi.org/10.1016/j.lungcan.2023.107445. Epub 2023 Dec 16. PMID: 38157805.

Article  CAS  PubMed  Google Scholar 

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. https://doi.org/10.1136/bmj.n71. PMID: 33782057; PMCID: PMC8005924.

Article  PubMed  PubMed Central  Google Scholar 

Higgins JPT, Thomas J, Chandler J, et al., editors. Cochrane handbook for systematic reviews of interventions version 6.3 (updated February 2022). Chichester: Cochrane; 2022. Available at: www.training.cochrane.org/handbook.

Deng C, Zheng Q, Zhang Y, Jin Y, Shen X, Nie X, Fu F, Ma X, Ma Z, Wen Z, Wang S, Li Y, Chen H. Validation of the novel International Association for the study of Lung Cancer grading system for invasive pulmonary adenocarcinoma and association with common driver mutations. J Thorac Oncol. 2021;16(10):1684–93. https://doi.org/10.1016/j.jtho.2021.07.006. Epub 2021 Jul 22. PMID: 34302987.

Article  CAS  PubMed  Google Scholar 

Fan J, Yao J, Si H, Xie H, Ge T, Ye W, Chen J, Yin Z, Zhuang F, Xu L, Su H, Zhao S, Xie X, Zhao D, Wu C, Zhu Y, Ren Y, Xu N, Chen C. Surgical Thoracic Alliance of Rising Star Group. Frozen sections accurately predict the IASLC proposed grading system and prognosis in patients with invasive lung adenocarcinomas. Lung Cancer. 2023;178:123–30. https://doi.org/10.1016/j.lungcan.2023.02.010. Epub 2023 Feb 17. PMID: 36822017.

Article  PubMed  Google Scholar 

Fujikawa R, Muraoka Y, Kashima J, Yoshida Y, Ito K, Watanabe H, Kusumoto M, Watanabe SI, Yatabe Y. Clinicopathologic and genotypic features of lung adenocarcinoma characterized by the international association for the study of lung cancer grading system. J Thorac Oncol. 2022;17(5):700–7. https://doi.org/10.1016/j.jtho.2022.02.005. Epub 2022 Feb 25. PMID: 35227909.

Article  CAS  PubMed  Google Scholar 

Hou L, Wang T, Chen D, She Y, Deng J, Yang M, Zhang Y, Zhao M, Zhong Y, Ma M, Zhao G, Chen Y, Xie D, Zhu Y, Chen Q, Wu C, Chen C, Multi-omics Classifier for Pulmonary Nodules (MISSION) Collaborative Group. Prognostic and predictive value of the newly proposed grading system of invasive pulmonary adenocarcinoma in Chinese patients: a retrospective multicohort study. Mod Pathol. 2022;35(6):749–56. https://doi.org/10.1038/s41379-021-00994-5. Epub 2022 Jan 10. PMID: 35013526.

Article  PubMed  Google Scholar 

Weng CF, Huang CJ, Huang SH, Wu MH, Tseng AH, Sung YC, Lee HH, Ling TY. New International Association for the Study of Lung Cancer (IASLC) Pathology Committee grading system for the prognostic outcome of advanced lung adenocarcinoma. Cancers (Basel). 2020;12(11):3426. https://doi.org/10.3390/cancers12113426. Erratum in: Cancers (Basel). 2021 Aug 10;13(16): PMID: 33218158; PMCID: PMC7698816.

Article  CAS  PubMed  Google Scholar 

Woo W, Yang YH, Cha YJ, Moon DH, Shim HS, Cho A, Kim BJ, Kim HE, Park BJ, Lee JG, Kim DJ, Paik HC, Lee S, Lee CY. Prognosis of resected invasive mucinous adenocarcinoma compared with the IASLC histologic grading system for invasive nonmucinous adenocarcinoma: surgical database study in the TKIs era in Korea. Thorac Cancer. 2022;13(23):3310–21. https://doi.org/10.1111/1759-7714.14687. Epub 2022 Nov 7. PMID: 36345148; PMCID: PMC9715870.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xu L, Su H, Hou L, Wang F, Xie H, She Y, Gao J, Zhao S, Dai C, Xie D, Zhu Y, Wu C, Zhao D, Chen C, Surgical Thoracic Alliance of Rising Star Group. The IASLC proposed grading system accurately predicts prognosis and mediastinal nodal metastasis in patients with clinical stage I lung adenocarcinoma. Am J Surg Pathol. 2022;46(12):1633–41. https://doi.org/10.1097/PAS.0000000000001876. Epub 2022 Oct 13. PMID: 36224092.

Article  CAS  PubMed  Google Scholar 

Yanagawa N, Sugai M, Shikanai S, Sugimoto R, Osakabe M, Uesugi N, Saito H, Maemondo M, Sugai T. The new IASLC grading system for invasive non-mucinous lung adenocarcinoma is a more useful indicator of patient survival compared with previous grading systems. J Surg Oncol. 2023;127(1):174–82. https://doi.org/10.1002/jso.27091. Epub 2022 Sep 13. PMID: 36098331.

Article  PubMed  Google Scholar