Lutz TA, Bueter M. Physiological mechanisms behind Roux-en-Y gastric bypass surgery. Dig Surg. 2014;31(1):13–24.

Article  PubMed  Google Scholar 

Linner JH. Comparative effectiveness of gastric bypass and gastroplasty: a clinical study. Arch Surg. 1982;117(5):695–700.

Article  PubMed  CAS  Google Scholar 

Mason EE. Surgical treatment of obesity. Major Probl Clin Surg. 1981;26:1–480.

PubMed  CAS  Google Scholar 

Brolin RE, et al. Long-limb gastric bypass in the superobese. A prospective Randomized Study Ann Surg. 1992;215(4):387–95.

PubMed  CAS  Google Scholar 

Gleysteen, J.J. Five-year outcome with gastric bypass: Roux limb length makes a difference. Surg Obes Relat Dis. 2009;5 2:242–7. discussion 247–9.

Susstrunk J, et al. Long-term outcome of proximal versus very-very long limb Roux-en-Y gastric bypass: the Roux-limb to common channel ratio determines the long-term weight loss. Obes Surg. 2021;31(3):994–1003.

Article  PubMed  Google Scholar 

Stefanidis D, Kuwada TS, Gersin KS. The importance of the length of the limbs for gastric bypass patients–an evidence-based review. Obes Surg. 2011;21(1):119–24.

Article  PubMed  Google Scholar 

Gadiot RPM, et al. Does the length of the common channel as part of the total alimentary tract matter? One year results from the multicenter Dutch common channel trial (DUCATI) Comparing standard versus distal Roux-en-Y gastric bypass with similar biliopancreatic bowel limb lengths. Obes Surg. 2020;30(12):4732–40.

Article  PubMed  Google Scholar 

Gadiot RPM, et al. Midterm results from the Dutch common channel trial (DUCATI): superior weight loss results of the long roux limb gastric bypass in comparison to the standard bypass at 3-year follow-up. Obes Surg. 2021;31(12):5132–40.

Article  PubMed  Google Scholar 

Orci L, Chilcott M, Huber O. Short versus long Roux-limb length in Roux-en-Y gastric bypass surgery for the treatment of morbid and super obesity: a systematic review of the literature. Obes Surg. 2011;21(6):797–804.

Article  PubMed  Google Scholar 

Darabi S, et al. The role of alimentary and biliopancreatic limb length in outcomes of Roux-en-Y gastric bypass. Wideochir Inne Tech Maloinwazyjne. 2020;15(2):290–7.

PubMed  Google Scholar 

Shah K, et al. Limb length in gastric bypass in super-obese patients-importance of length of total alimentary small bowel tract. Obes Surg. 2019;29(7):2012–21.

Article  PubMed  Google Scholar 

Boerboom A, et al. A long biliopancreatic and short alimentary limb results in more weight loss in revisional RYGB surgery. Outcomes of the randomized controlled ELEGANCE REDO trial. Surg Obes Relat Dis. 2019;15(1):60–9.

Article  PubMed  Google Scholar 

Eskandaros MS, Abbass A. Standard biliopancreatic limb (50 cm) Roux-en-Y gastric bypass versus long biliopancreatic limb (100 cm) Roux-en-Y gastric bypass in patients with body mass index 40–50 kg/m(2): a randomized prospective study. Obes Surg. 2022;32(3):577–86.

Article  PubMed  Google Scholar 

Nergaard BJ, et al. Gastric bypass with long alimentary limb or long pancreato-biliary limb–long-term results on weight loss, resolution of co-morbidities and metabolic parameters. Obes Surg. 2014;24(10):1595–602.

Article  PubMed  PubMed Central  Google Scholar 

Stevenson M, et al. Beyond measure: navigating the complexities of limb length optimization in Roux-en-Y gastric bypass surgery. Obes Surg. 2024;34(7):2691–3.

Article  PubMed  Google Scholar 

Schneider R, et al. Roux-en-Y gastric bypass with a long versus a short biliopancreatic limb improves weight loss and glycemic control in obese mice. Surg Obes Relat Dis. 2022;18(11):1286–97.

Article  PubMed  Google Scholar 

Hao Z, et al. Development and verification of a mouse model for Roux-en-Y gastric bypass surgery with a small gastric pouch. PLoS ONE. 2013;8(1):e52922.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Mina AI, et al. CalR: A web-based analysis tool for indirect calorimetry experiments. Cell Metab. 2018;28 4:656–666 e1.

Walters WA, et al. PrimerProspector: de novo design and taxonomic analysis of barcoded polymerase chain reaction primers. Bioinformatics. 2011;27(8):1159–61.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Caporaso, J.G., et al. Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample. Proc Natl Acad Sci U S A, 2011;108 Suppl 1(Suppl 1):4516–22.

Kechin A, et al. cutPrimers: a new tool for accurate cutting of primers from reads of targeted next generation sequencing. J Comput Biol. 2017;24(11):1138–43.

Article  PubMed  CAS  Google Scholar 

Bolyen E, et al. Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2. Nat Biotechnol. 2019;37(8):852–7.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Callahan BJ, et al. DADA2: High-resolution sample inference from Illumina amplicon data. Nat Methods. 2016;13(7):581–3.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Quast C et al. The SILVA ribosomal RNA gene database project: improved data processing and web-based tools. Nucleic Acids Res, 2013;41(Database issue):D590–6.

Shannon CE The mathematical theory of communication. 1963. MD Comput. 1997;14 4:306–17.

McArdle BH, Anderson MJ. Fitting multivariate models to community data: a comment on distance-based redundancy analysis. Ecology. 2001;82(1):290–7.

Article  Google Scholar 

McMurdie PJ, Holmes S. phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data. PLoS ONE. 2013;8(4):e61217.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Gu Z, Eils R, Schlesner M. Complex heatmaps reveal patterns and correlations in multidimensional genomic data. Bioinformatics. 2016;32(18):2847–9.

Article  PubMed  CAS  Google Scholar 

Stevenson M, et al. The effect of diet composition on the post-operative outcomes of Roux-en-Y gastric bypass in mice. Obes Surg. 2024;34(3):911–27.

Article  PubMed  Google Scholar 

Tabasi M, et al. Changes in gut microbiota and hormones after bariatric surgery: a bench-to-bedside review. Obes Surg. 2019;29(5):1663–74.

Article  PubMed  Google Scholar 

Gasmi A, et al. Gut microbiota in bariatric surgery. Crit Rev Food Sci Nutr. 2023;63(28):9299–314.

Article  PubMed  CAS  Google Scholar 

Tacchino RM. Bowel length: measurement, predictors, and impact on bariatric and metabolic surgery. Surg Obes Relat Dis. 2015;11(2):328–34.

Article  PubMed  Google Scholar 

Bekheit M, et al. Correlation between the total small bowel length and anthropometric measures in living humans: cross-sectional study. Obes Surg. 2020;30(2):681–6.

Article  PubMed  Google Scholar 

Eagleston J, Nimeri A. Optimal small bowel limb lengths of Roux-en-Y gastric bypass. Curr Obes Rep. 2023;12(3):345–54.

Article  PubMed  Google Scholar 

Liou AP et al. Conserved shifts in the gut microbiota due to gastric bypass reduce host weight and adiposity. Sci Transl Med. 2013;5 178:178ra41.

Hao Z, et al. Leptin deficient ob/ob mice and diet-induced obese mice responded differently to Roux-en-Y bypass surgery. Int J Obes (Lond). 2015;39(5):798–805.

Article  PubMed  CAS  Google Scholar 

Nestoridi E, et al. Resting energy expenditure and energetic cost of feeding are augmented after Roux-en-Y gastric bypass in obese mice. Endocrinology. 2012;153(5):2234–44.

Article  PubMed  CAS  Google Scholar 

Miras AD et al. in Long limb compared with standard limb Roux-en-Y gastric bypass for type 2 diabetes and obesity: the LONG LIMB RCT. 2021: Southampton (UK).

Paccou J, et al. Bariatric surgery and skeletal health: a narrative review and position statement for management by the European Calcified Tissue Society (ECTS). Bone. 2022;154:116236.

Article  PubMed