Barroso WKS, Rodrigues CIS, Bortolotto LA, et al. Brazilian guidelines for hypertension, 2020. Arq Bras Cardiol. 2021;116:516–658. https://doi.org/10.36660/abc.20201238.

Article  PubMed  PubMed Central  Google Scholar 

Barnett K, Mercer SW, Norbury M, et al. Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study. Lancet. 2012;380:37–43. https://doi.org/10.1016/S0140-6736(12)60240-2.

Article  PubMed  Google Scholar 

Marques AP, Szwarcwald CL, Pires DC, et al. Factors associated with arterial hypertension: a systematic review. Cien Saúde Colet. 2020;25:2271–82. https://doi.org/10.1590/1413-81232020256.26972018.

Article  PubMed  Google Scholar 

Bai I, Isenor JE, Reeve E, et al. The behavioural change wheel was used to link published deprescribing strategies to identify local primary healthcare needs. Res Soc Adm Pharm. 2022;18:3350–7. https://doi.org/10.1016/j.sapharm.2021.12.001.

Article  Google Scholar 

Brazil MoH. [Elderly Health: Thematic Bulletin 2022]. Brasília: Ministry of Health. https://bvsms.saude.gov.br/bvs/boletim_tematico/saude_idoso_outubro_2022-1.pdf. Accessed 10 Aug 2023.

Gijón-Conde T, Gorostidi M, Banegas JR, et al. Position statement on ambulatory blood pressure monitoring (ABPM) by the Spanish Society of Hypertension (2019). Hipertens Riesgo Vasc. 2019;36:199–212. https://doi.org/10.1016/j.hipert.2019.05.002.

Article  PubMed  Google Scholar 

Brandão AA, Alessi A, Feitosa AM, et al. VI Brazilian guidelines for ambulatory monitoring of arterial pressure and IV Brazilian guidelines for home monitoring of blood pressure. Arq Bras Cardiol. 2018;110:1–3. https://doi.org/10.5935/abc.20180074.

Article  Google Scholar 

Velten APC, Benseñor I, Souza JB, et al. Factors associated with orthostatic hypotension in adults: the ELSA-Brazil study. Cad Saude Publica. 2019;35:e00123718. https://doi.org/10.1590/0102-311X00123718.

Article  PubMed  Google Scholar 

Grezzana GB, Stein AT. 24-hour ambulatory blood pressure monitoring predicts the outcomes of patients with hypertension in primary care: a cohort study. Int J Cardiovasc Sci. 2017;30:285–92. https://doi.org/10.5935/2359-4802.20170061.

Article  Google Scholar 

Moreno JN, Amorim WW, Mistro S, et al. Evaluation of blood pressure through home monitoring in Brazilian primary care: a feasibility study. Cien Saúde Colet. 2021;26:2997–3004. https://doi.org/10.1590/1413-81232021268.17012020.

Article  PubMed  Google Scholar 

Reeve E, Gnjidic D, Long J, et al. A systematic review of the emerging definition of ‘deprescribing’with network analysis: implications for future research and clinical practice. Br J Clin Pharmacol. 2015;80:1254–68. https://doi.org/10.1111/bcp.12732.

Article  PubMed  PubMed Central  Google Scholar 

Conklin J, Farrell B, Suleman S. Implementing deprescribing guidelines into frontline practice: barriers and facilitators. Res Soc Adm Pharm. 2019;15:796–800. https://doi.org/10.1016/j.sapharm.2018.08.012.

Article  Google Scholar 

Johansson T, Abuzahra ME, Keller S, et al. Impact of strategies to reduce polypharmacy on clinically relevant endpoints: a systematic review and meta-analysis. Br J Clin Pharmacol. 2016;82:532–48. https://doi.org/10.1111/bcp.12959.

Article  PubMed  PubMed Central  Google Scholar 

Mangin D, Bahat G, Golomb BA, et al. International group for reducing inappropriate medication use and polypharmacy (IGRIMUP): position statement and ten recommendations for action. Drugs Aging. 2018;35:575–87. https://doi.org/10.1007/s40266-018-0554-2.

Article  PubMed  PubMed Central  Google Scholar 

Zechmann S, Senn O, Valeri F, et al. Effect of a patient-centred deprescribing procedure in older multimorbid patients in Swiss primary care—a cluster-randomised clinical trial. BMC Geriatr. 2020;20:471. https://doi.org/10.1186/s12877-020-01870-8.

Article  PubMed  PubMed Central  Google Scholar 

Poots AJ, Jubraj B, Barnett NL. Education around deprescribing: ‘spread and embed’ the story so far. Eur J Hosp Pharm. 2017;24:7–9. https://doi.org/10.1136/ejhpharm-2016-001153.

Article  PubMed  PubMed Central  Google Scholar 

Linsky A, Gellad WF, Linder JA. Advancing the science of depression: a novel comprehensive conceptual framework. J Am Geriatr Soc. 2019;67:2018–22. https://doi.org/10.1111/jgs.16136.

Article  PubMed  PubMed Central  Google Scholar 

Sgnaolin V, Engroff P. Desprescrição. Pan Am J Aging Res. 2019;7(2):34609. https://doi.org/10.15448/2357-9641.2019.2.34609.

Article  Google Scholar 

Moreira PM, Aguiar EC, Castro PR, et al. Optimising hypertension treatment in older patients through home blood pressure monitoring by pharmacists in primary care: the MINOR clinical trial. Clin Ther. 2023;45:941–6. https://doi.org/10.1016/j.clinthera.2023.06.007.

Article  PubMed  Google Scholar 

Primary Health Tasmania. A guide to deprescribing antihypertensives. Primary Health Tasmania; 2022. Available from: http://www.primaryhealthtas.com.au. Accessed 10 Aug 2023.

Freeman R, Wieling W, Axelrod FB, et al. Consensus statement on the definitions of orthostatic hypotension, neurally mediated syncope, and postural tachycardia syndrome. Auton Neurosci. 2011;161:46–8. https://doi.org/10.1016/j.autneu.2011.02.004.

Article  PubMed  Google Scholar 

Sheppard JP, Lown M, Burt J, et al. Generalizability of blood pressure lowering trials to older patients: cross-sectional analysis. J Am Geriatr Soc. 2020;68:2508–15. https://doi.org/10.1111/jgs.16749.

Article  PubMed  Google Scholar 

Scott IA, Hilmer SN, Le Couteur DG. Going beyond the guidelines in individualising the use of antihypertensive drugs in older patients. Drugs Aging. 2019;36:675–85. https://doi.org/10.1007/s40266-019-00683-8.

Article  PubMed  Google Scholar 

Benetos A, Labat C, Rossignol P, et al. Treatment with multiple blood pressure medications, achieved blood pressure, and mortality in older nursing home residents: the partage study. JAMA Intern Med. 2015;175:989–95. https://doi.org/10.1001/jamainternmed.2014.8012.

Article  CAS  PubMed  Google Scholar 

Gulla C, Flo E, Kjome RL, et al. Deprescribing antihypertensive treatment in nursing home patients and the effect on blood pressure. J Geriatr Cardiol JGC. 2018;15:275–83. https://doi.org/10.11909/j.issn.1671-5411.2018.04.011.

Article  PubMed  Google Scholar 

Trenaman SC, Kennie-Kaulbach N, d’Entremont-MacVicar E, et al. Implementation of pharmacist-led deprescribing in collaborative primary care settings. Int J Clin Pharm. 2022;44:1216–21. https://doi.org/10.1007/s11096-022-01449-w.

Article  PubMed  PubMed Central  Google Scholar 

Chan M, Plakogiannis R, Stefanidis A, et al. Pharmacist-led deprescribing for patients with polypharmacy and chronic disease states: a retrospective cohort study. J Pharm Pract. 2023;36:1192–200. https://doi.org/10.1177/08971900221097246.

Article  PubMed  Google Scholar 

Juraschek SP, Cluett JL, Belanger MJ, et al. Effects of antihypertensive deprescribing strategies on blood pressure, adverse events, and orthostatic symptoms in older adults: results from TONE. Am J Hypertens. 2022;35:337–46. https://doi.org/10.1093/ajh/hpab171.

Article  CAS  PubMed  Google Scholar 

Wiysonge CS, Bradley HA, Volmink J, et al. Beta-blockers for hypertension. Cochrane Database Syst Rev. 2017. https://doi.org/10.1002/14651858.CD002003.pub5.

Article  PubMed  PubMed Central  Google Scholar 

Bangalore S, Messerli FH, Kostis JB, et al. Cardiovascular protection using beta-blockers: a critical review of the evidence. J Am Coll Cardiol. 2007;50:563–72. https://doi.org/10.1016/j.jacc.2007.04.060.

Article  CAS  PubMed  Google Scholar 

Stortecky S, Schoenenberger AW, Moser A, et al. Evaluation of multidimensional geriatric assessment as a predictor of mortality and cardiovascular events after transcatheter aortic valve implantation. JACC Cardiovasc Interv. 2012;5:489–96. https://doi.org/10.1016/j.jcin.2012.02.012.

Article  PubMed  Google Scholar