MS: Novartis: Speakers Bureau; Pfizer: Honoraria, Membership on an entity’s Board of Directors or advisory committees, Research Funding, Speakers Bureau; MSD: Membership on an entity’s Board of Directors or advisory committees, Speakers Bureau; Amgen: Membership on an entity’s Board of Directors or advisory committees; medac: Other: Editorial and statistical support, Speakers Bureau; Gilead: Speakers Bureau; Jazz: Speakers Bureau; Abbvie: Speakers Bureau. KS: Blueprint: Consultancy, Honoraria; GSK: Consultancy, Honoraria; SOBI: Consultancy, Honoraria; Gilead: Consultancy, Honoraria; BMS/Celgene: Consultancy, Honoraria; Novartis: Consultancy, Honoraria; Active Biotech: Research Funding. MF: No relevant disclosures. Johannes Schetelig: Novartis: Honoraria; BMS: Consultancy, Honoraria; Abbvie: Consultancy, Honoraria; Janssen: Consultancy, Honoraria; AstraZeneca: Consultancy, Honoraria; Eurocept: Honoraria; BeiGene: Consultancy, Honoraria. MB: No relevant disclosures. CR: No relevant disclosures. GL, all disclosures not related to this manuscript: Hexal/Sandoz: Consultancy, Membership on an entity’s Board of Directors or advisory committees, Speakers Bureau; Genase: Consultancy; Immagene: Consultancy; BeiGene: Membership on an entity’s Board of Directors or advisory committees; SOBI: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees, Speakers Bureau; PentixPharm: Consultancy, Membership on an entity’s Board of Directors or advisory committees; Miltenyi: Consultancy, Membership on an entity’s Board of Directors or advisory committees; ADC Therapeutics: Consultancy, Membership on an entity’s Board of Directors or advisory committees; Constellation: Consultancy, Membership on an entity’s Board of Directors or advisory committees; Karyopharm: Consultancy, Membership on an entity’s Board of Directors or advisory committees; Genmab: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees; Morphosys: Consultancy, Membership on an entity’s Board of Directors or advisory committees, Research Funding, Speakers Bureau; Incyte: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees, Speakers Bureau; AbbVie: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees, Speakers Bureau; BMS: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees, Speakers Bureau; Takeda: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees, Speakers Bureau; Lilly: Consultancy; University Hospital Munster: Current Employment; Celgene: Membership on an entity’s Board of Directors or advisory committees, Research Funding, Speakers Bureau; NanoString: Membership on an entity’s Board of Directors or advisory committees; AstraZeneca: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees, Research Funding, Speakers Bureau; Novartis: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees, Research Funding, Speakers Bureau; Bayer: Consultancy, Membership on an entity’s Board of Directors or advisory committees, Research Funding, Speakers Bureau; Janssen: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees, Research Funding, Speakers Bureau; Gilead: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees, Research Funding, Speakers Bureau; F. Hoffmann-La Roche Ltd: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees, Research Funding, Speakers Bureau. TS: medac: Speaker Honoria, Travel grants. MM: No relevant disclosures. HL-W: No relevant disclosures. Péter Reményi: No relevant disclosures. FC: ExCellThera: Other: Scientific Advisory Board. Imran Khan: medac: Employee of medac. Uwe Pichlmeier: medac: Employee of medac. XL: medac: Employee of medac. Friedrich Stölzel: medac: Speakers Bureau. Servier: Speakers Bureau. Jazz: Speakers Bureau. Servier, Johnson & Johnson, medac: Travel Funding. Astellas: Speakers Bureau.