Martin, L. et al. Diagnostic criteria for cancer cachexia: reduced food intake and inflammation predict weight loss and survival in an international, multi-cohort analysis. J. Cachexia Sarcopenia Muscle 12, 1189–1202 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Babic, A. et al. Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer. Nat. Commun. 14, 4317 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Klassen, P., Schiessel, D. L. & Baracos, V. E. Adverse effects of systemic cancer therapy on skeletal muscle: myotoxicity comes out of the closet. Curr. Opin. Clin. Nutr. Metab. Care 26, 210–218 (2023).

CAS  PubMed  Google Scholar 

Roeland, E. J., Bohlke, K., Baracos, V. E., Smith, T. J. & Loprinzi, C. L. Cancer cachexia: ASCO guideline rapid recommendation update. J. Clin. Oncol. 41, 4178–4179 (2023).

Article  PubMed  Google Scholar 

Sandhya, L. et al. Randomized double-blind placebo-controlled study of olanzapine for chemotherapy-related anorexia in patients with locally advanced or metastatic gastric, hepatopancreaticobiliary, and lung cancer. J. Clin. Oncol 41, 2617–2627 (2023).

Article  CAS  PubMed  Google Scholar 

Groarke, J. D. et al. Ponsegromab for the treatment of cancer cachexia. N. Engl. J. Med. https://doi.org/10.1056/NEJMoa2409515 (2024).

Article  PubMed  Google Scholar 

Kadakia, K. C., Hamilton-Reeves, J. M. & Baracos, V. E. Current therapeutic targets in cancer cachexia: a pathophysiologic approach. Am. Soc. Clin. Oncol. Educ. Book 43, e389942 (2023).

Article  PubMed  PubMed Central  Google Scholar 

Roeland, E. J. et al. Management of cancer cachexia: ASCO guideline. J. Clin. Oncol. 38, 2438–2453 (2020).

Article  CAS  PubMed  Google Scholar 

Temel, J. S. et al. Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials. Lancet Oncol 17, 519–531 (2016).

Article  CAS  PubMed  Google Scholar 

Amano, K. et al. Development and validation of questionnaires for eating-related distress among advanced cancer patients and families. J. Cachexia Sarcopenia Muscle 14, 310–325 (2023).

Article  PubMed  Google Scholar