PTP1B inhibitor alleviates deleterious septic lung injury through Src signaling

Abdullahi A, Stanojcic M, Parousis A et al (2017) Modeling acute ER stress in Vivo and in Vitro. Shock 47:506–513. https://doi.org/10.1097/SHK.0000000000000759

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ajoolabady A, Lebeaupin C, Wu NN et al (2023) ER stress and inflammation crosstalk in obesity. Med Res Rev 43:5–30. https://doi.org/10.1002/med.21921

Article  CAS  PubMed  Google Scholar 

Bourebaba L, Serwotka-Suszczak A, Pielok A et al (2023) The PTP1B inhibitor MSI-1436 ameliorates liver insulin sensitivity by modulating autophagy, ER stress and systemic inflammation in equine metabolic syndrome affected horses. Front Endocrinol (Lausanne) 14:1149610. https://doi.org/10.3389/fendo.2023.1149610

Article  PubMed  Google Scholar 

Cui Y, Yang Y, Tao W et al (2023) Neutrophil Extracellular traps induce alveolar macrophage pyroptosis by regulating NLRP3 deubiquitination, aggravating the Development of Septic Lung Injury. J Inflamm Res 16:861–877. https://doi.org/10.2147/JIR.S366436

Article  CAS  PubMed  PubMed Central  Google Scholar 

Heinonen KM, Dube N, Bourdeau A et al (2006) Protein tyrosine phosphatase 1B negatively regulates macrophage development through CSF-1 signaling. Proc Natl Acad Sci USA 103:2776–2781. https://doi.org/10.1073/pnas.0508563103

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang J, Lu W, Doycheva DM et al (2020) IRE1alpha inhibition attenuates neuronal pyroptosis via miR-125/NLRP1 pathway in a neonatal hypoxic-ischemic encephalopathy rat model. J Neuroinflammation 17:152. https://doi.org/10.1186/s12974-020-01796-3

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hui Z, Wang S, Li J et al (2022) Compound Tongluo Decoction inhibits endoplasmic reticulum stress-induced ferroptosis and promoted angiogenesis by activating the Sonic hedgehog pathway in cerebral infarction. J Ethnopharmacol 283:114634. https://doi.org/10.1016/j.jep.2021.114634

Article  CAS  PubMed  Google Scholar 

Kim DI, Song MK, Kim HI et al (2020) Diesel Exhaust particulates Induce Neutrophilic Lung inflammation by modulating endoplasmic reticulum stress-mediated CXCL1/KC expression in alveolar macrophages. Molecules 25. https://doi.org/10.3390/molecules25246046

Lebeaupin C, Proics E, de Bieville CH et al (2015) ER stress induces NLRP3 inflammasome activation and hepatocyte death. Cell Death Dis 6:e1879. https://doi.org/10.1038/cddis.2015.248

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee S, Park S, Ryu JS et al (2023) c-Src inhibitor PP2 inhibits head and neck cancer progression through regulation of the epithelial-mesenchymal transition. Exp Biol Med (Maywood) 248:492–500. https://doi.org/10.1177/15353702221139183

Article  CAS  PubMed  Google Scholar 

Lennmyr F, Ericsson A, Gerwins P et al (2004) Src family kinase-inhibitor PP2 reduces focal ischemic brain injury. Acta Neurol Scand 110:175–179. https://doi.org/10.1111/j.1600-0404.2004.00306.x

Article  CAS  PubMed  Google Scholar 

Liu ST, Pham H, Pandol SJ et al (2013) Src as the link between inflammation and cancer. Front Physiol 4:416. https://doi.org/10.3389/fphys.2013.00416

Article  PubMed  Google Scholar 

Liu H, Wu Y, Zhu S et al (2015) PTP1B promotes cell proliferation and metastasis through activating src and ERK1/2 in non-small cell lung cancer. Cancer Lett 359:218–225. https://doi.org/10.1016/j.canlet.2015.01.020

Article  CAS  PubMed  Google Scholar 

Luo D, Liu F, Zhang J et al (2021) Comprehensive analysis of LncRNA-mRNA expression profiles and the ceRNA Network Associated with pyroptosis in LPS-Induced Acute Lung Injury. J Inflamm Res 14:413–428. https://doi.org/10.2147/JIR.S297081

Article  PubMed  PubMed Central  Google Scholar 

Matthay MA, Ware LB, Zimmerman GA (2012) The acute respiratory distress syndrome. J Clin Invest 122:2731–2740. https://doi.org/10.1172/JCI60331

Sharma B, Xie L, Yang F et al (2020) Recent advance on PTP1B inhibitors and their biomedical applications. Eur J Med Chem 199:112376. https://doi.org/10.1016/j.ejmech.2020.112376

Article  CAS  PubMed  Google Scholar 

Song GJ, Jung M, Kim JH et al (2016) A novel role for protein tyrosine phosphatase 1B as a positive regulator of neuroinflammation. J Neuroinflammation 13:86. https://doi.org/10.1186/s12974-016-0545-3

Article  CAS  PubMed  PubMed Central  Google Scholar 

Song D, Adrover JM, Felice C et al (2022) PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils. JCI Insight 7. https://doi.org/10.1172/jci.insight.158199

Article  Google Scholar 

Thompson BT, Chambers RC, Liu KD (2017) Acute respiratory distress syndrome. N Engl J Med 377:562–572. https://doi.org/10.1056/NEJMra1608077

Article  CAS  PubMed  Google Scholar 

Toscano MG, Ganea D, Gamero AM (2011) Cecal ligation puncture procedure. J Vis Exp 7:2860. https://doi.org/10.3791/2860

Wei JX, Jiang HL, Chen XH (2023) Endothelial cell metabolism in sepsis. World J Emerg Med 14:10–16. https://doi.org/10.5847/wjem.j.1920-8642.2023.019

Article  PubMed  PubMed Central  Google Scholar 

Xie K, Chen YQ, Chai YS et al (2021) HMGB1 suppress the expression of IL-35 by regulating naive CD4 + T cell differentiation and aggravating caspase-11-dependent pyroptosis in acute lung injury. Int Immunopharmacol 91:107295. https://doi.org/10.1016/j.intimp.2020.107295

Article  CAS  PubMed  Google Scholar 

Xu X, Wang X, Guo Y et al (2019) Inhibition of PTP1B promotes M2 polarization via MicroRNA-26a/MKP1 signaling pathway in murine macrophages. Front Immunol 10(1930). https://doi.org/10.3389/fimmu.2019.01930

Zhang J, Guo J, Yang N et al (2022) Endoplasmic reticulum stress-mediated cell death in liver injury. Cell Death Dis 13:1051. https://doi.org/10.1038/s41419-022-05444-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhu Y, Yu J, Gong J et al (2021) PTP1B inhibitor alleviates deleterious microglial activation and neuronal injury after ischemic stroke by modulating the ER stress-autophagy axis via PERK signaling in microglia. Aging 13:3405–3427. https://doi.org/10.18632/aging.202272

Article  CAS  PubMed  PubMed Central  Google Scholar 

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