Erica K. Sloan Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Victoria 3052, Australia Corresponding author: erica.sloanmonash.edu Abstract

Solid tumors that arise in the body interact with neurons, which influences cancer progression and treatment response. Here, we discuss key questions in the field, including defining the nature of interactions between tumors and neural circuits and defining how neural signals shape the tumor microenvironment. This information will allow us to optimally target neural signaling to improve outcomes for cancer patients.