The temporomandibular joint (TMJ) helps to perform the functional activities of the oral cavity. Such activities often get affected by end-stage degenerative disorders such as TMJ ankylosis. Alloplastic reconstruction using TMJ implants helps to restore those activities. However, commercially available stock implants often suffer from fit discrepancies in Indian population. Therefore, this study is aimed to compare comparison between mandibular morphometry of subjects with healthy or normal TMJ joints (TMJN) and patients with TMJ ankylosis (TMJA) from the Indian population. Furthermore, the observed mandibular morphometry has also been compared with those of the other populations. In this study, the most useful anatomical parameters of mandible are measured from the CT-based reconstructed mandibles of 367 Indian subjects (199 healthy;168 ankylosis). Significant differences in ramus length (healthy males: 61.74±7.53 mm, ankylosis males: 46.81±10.35 mm; healthy females: 55.21±6.12 mm, ankylosis females: 41.77±8.57 mm) and condyle width (healthy males: 18.76±3.22 mm, ankylosis males: 22.67±5.56 mm; healthy females: 16.94±2.41 mm, ankylosis females: 21.31±4.65 mm) have been observed between mandibles of ankylosis and healthy subjects. Differences in ramus length (affected side: 43.87±9.51 mm; unaffected side: 55.34±7.12 mm) and condyle width (affected side: 23±4.68 mm; unaffected side: 17.99±2.81 mm) were also observed between affected and unaffected sides of mandibles for unilateral ankylosis patients. Ramus length in healthy subjects was found to be the most statistically significant parameter between mandibles of Indians and other populations.
Competing Interest StatementThe authors have declared no competing interest.
Funding StatementThe authors would like to acknowledge the Indo-German Science and Technology Centre (Grant no. IGSTC/Call 2020/add-bite/48/2021-22/260) for the funding.
Author DeclarationsI confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Yes
The details of the IRB/oversight body that provided approval or exemption for the research described are given below:
Ethics committee/IRB of All India Institute of Medical Sciences New Delhi, India gave ethical approval for this work.
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Yes
I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).
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I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.
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Data AvailabilityThe data that support the findings of this study are available from the corresponding author upon reasonable request.
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