Jiang XT, Liu Q. mRNA vaccination in breast cancer: current progress and future direction. J Cancer Res Clin Oncol. 2023;149(11):9435–50.

Article  PubMed  Google Scholar 

Takeda K, Komuro Y, Hayakawa T, Oguchi H, Ishida Y, Murakami S, Noguchi T, Kinoshita H, Sekine Y, Iemura S, et al. Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1. Proc Natl Acad Sci U S A. 2009;106(30):12301–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

He GW, Gunther C, Kremer AE, Thonn V, Amann K, Poremba C, Neurath MF, Wirtz S, Becker C. PGAM5-mediated programmed necrosis of hepatocytes drives acute liver injury. Gut. 2017;66(4):716–23.

Article  CAS  PubMed  Google Scholar 

Ramachandran A, Jaeschke H. PGAM5: a new player in immune-mediated liver injury. Gut. 2017;66(4):567–8.

Article  CAS  PubMed  Google Scholar 

Wang Z, Jiang H, Chen S, Du F, Wang X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell. 2012;148(1–2):228–43.

Article  CAS  PubMed  Google Scholar 

Meng L, Hu P, Xu A. PGAM5 promotes tumorigenesis of gastric cancer cells through PI3K/AKT pathway. Pathol Res Pract. 2023;244:154405.

Article  CAS  PubMed  Google Scholar 

Peng J, Wang T, Yue C, Luo X, Xiao P. PGAM5: a necroptosis gene associated with poor tumor prognosis that promotes cutaneous melanoma progression. Front Oncol. 2022;12:1004511.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang X, Stockwell BR, Conrad M. Ferroptosis: mechanisms, biology and role in disease. Nat Rev Mol Cell Biol. 2021;22(4):266–82.

Article  PubMed  PubMed Central  Google Scholar 

Fu G, Li ST, Jiang Z, Mao Q, Xiong N, Li X, et al. PGAM5 deacetylation mediated by SIRT2 facilitates lipid metabolism and liver cancer proliferation. Acta Biochim Biophys Sin (Shanghai). 2023;55(9):1370–9.

Mao C, Liu X, Zhang Y, Lei G, Yan Y, Lee H, Koppula P, Wu S, Zhuang L, Fang B, et al. DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer. Nature. 2021;593(7860):586–90.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kraft VAN, Bezjian CT, Pfeiffer S, Ringelstetter L, Muller C, Zandkarimi F, Merl-Pham J, Bao X, Anastasov N, Kossl J, et al. GTP cyclohydrolase 1/Tetrahydrobiopterin counteract ferroptosis through lipid remodeling. ACS Cent Sci. 2020;6(1):41–53.

Article  CAS  PubMed  Google Scholar 

Garcia DA, Baek C, Estrada MV, Tysl T, Bennett EJ, Yang J, Chang JT. USP11 enhances TGFbeta-Induced epithelial-mesenchymal plasticity and human breast Cancer Metastasis. Mol Cancer Res. 2018;16(7):1172–84.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dwane L, O’Connor AE, Das S, Moran B, Mulrane L, Pinto-Fernandez A, Ward E, Blumel AM, Cavanagh BL, Mooney B, et al. A functional genomic screen identifies the deubiquitinase USP11 as a Novel Transcriptional Regulator of ERalpha in breast Cancer. Cancer Res. 2020;80(22):5076–88.

Article  CAS  PubMed  Google Scholar 

Salem IM, Mostafa SM, Salama I, El-Sabbagh OI, Hegazy WAH, Ibrahim TS. Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors. J Enzyme Inhib Med Chem. 2023;38(1):203–15.

Article  CAS  PubMed  Google Scholar 

Liu WJ, Wang LY, Sheng Z, Zhang B, Zou X, Zhang CY. RNA methylation-driven assembly of fluorescence-encoded nanostructures for sensitive detection of m(6)a modification writer METTL3/14 complex in human breast tissues. Biosens Bioelectron. 2023;240:115645.

Article  CAS  PubMed  Google Scholar 

Zhang S, Guo A, Wang H, Liu J, Dong C, Ren J, Wang G. Oncogenic MORC2 in cancer development and beyond. Genes Dis. 2024;11(2):861–73.

Article  CAS  PubMed  Google Scholar 

Sadri F, Hosseini SF, Rezaei Z, Fereidouni M. Hippo-YAP/TAZ signaling in breast cancer: reciprocal regulation of microRNAs and implications in precision medicine. Genes Dis. 2024;11(2):760–71.

Article  CAS  PubMed  Google Scholar 

Papatsirou M, Scorilas A, Sideris DC, Kontos CK. Targeted nanopore sequencing for the identification of novel PRMT1 circRNAs unveils a diverse transcriptional profile of this gene in breast cancer cells. Genes Dis. 2024;11(2):589–92.

Article  CAS  PubMed  Google Scholar 

Zhong C, Niu Y, Liu W, Yuan Y, Li K, Shi Y, Qiu Z, Li K, Lin Z, Huang Z, et al. S100A9 Derived from Chemoembolization-Induced Hypoxia governs mitochondrial function in Hepatocellular Carcinoma Progression. Adv Sci (Weinh). 2022;9(30):e2202206.

Article  PubMed  Google Scholar 

Yan HF, Zou T, Tuo QZ, Xu S, Li H, Belaidi AA, Lei P. Ferroptosis: mechanisms and links with diseases. Signal Transduct Target Ther. 2021;6(1):49.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yuan Y, Zhai Y, Chen J, Xu X, Wang H. Kaempferol Ameliorates Oxygen-Glucose Deprivation/Reoxygenation-Induced Neuronal Ferroptosis by Activating Nrf2/SLC7A11/GPX4 Axis. Biomolecules 2021, 11(7).

Chen X, Kang R, Kroemer G, Tang D. Broadening horizons: the role of ferroptosis in cancer. Nat Rev Clin Oncol. 2021;18(5):280–96.

Article  CAS  PubMed  Google Scholar 

Liu M, Kong XY, Yao Y, Wang XA, Yang W, Wu H, Li S, Ding JW, Yang J. The critical role and molecular mechanisms of ferroptosis in antioxidant systems: a narrative review. Ann Transl Med. 2022;10(6):368.

Article  PubMed  PubMed Central  Google Scholar 

Jacko AM, Nan L, Li S, Tan J, Zhao J, Kass DJ, Zhao Y. De-ubiquitinating enzyme, USP11, promotes transforming growth factor beta-1 signaling through stabilization of transforming growth factor beta receptor II. Cell Death Dis. 2016;7(11):e2474.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ke JY, Dai CJ, Wu WL, Gao JH, Xia AJ, Liu GP, Lv KS, Wu CL. USP11 regulates p53 stability by deubiquitinating p53. J Zhejiang Univ Sci B. 2014;15(12):1032–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Deng T, Xie L, Xiaofang C, Zhang Z, Xiao Y, Peng Y, et al. ATM-Mediated translocation of RanBPM regulates DNA damage response by stabilizing p21 in non-small cell lung cancer cells. Cell Oncol (Dordr). 2023;47(1):245–8.

Jin Q, Gutierrez Diaz B, Pieters T, Zhou Y, Narang S, Fijalkwoski I, Borin C, Van Laere J, Payton M, Cho BK, et al. Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia. Sci Adv. 2022;8(49):eabq8437.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun H, Ou B, Zhao S, Liu X, Song L, Liu X, Wang R, Peng Z. USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway. EBioMedicine. 2019;48:236–47.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang S, Xie C, Li H, Zhang K, Li J, Wang X, Yin Z. Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma. Lab Invest. 2018;98(7):883–94.

Article  CAS  PubMed  Google Scholar 

Zhu X, Zhang Y, Luo Q, Wu X, Huang F, Shu T, Wan Y, Chen H, Liu Z. The deubiquitinase USP11 promotes ovarian cancer chemoresistance by stabilizing BIP. Signal Transduct Target Ther. 2021;6(1):264.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu H, Liu M, He B, Li Q. Inhibition of USP11 sensitizes gastric cancer to chemotherapy via suppressing RhoA and ras-mediated signaling pathways. Clin Res Hepatol Gastroenterol. 2022;46(1):101779.