Front. Oncol.

Sec. Cancer Metabolism

Volume 14 - 2024 | doi: 10.3389/fonc.2024.1455022

This article is part of the Research Topic Metabolism, Gut Microbiome, and Cancer View all articles

Provisionally accepted

Pradeep MK Nair 1* Karishma Silwal 2 Renganathan Ramalakshi 1 Muniappan Devibala 1 Maruthanayagam Saranya 1 Sekar Sivaranjan 1 Thangavelu R 1 Ayyappan Palanisamy 1 Manickam Mahalingam 1 1 Mirakle Integrated Health Centre, Pollachi, India 2 Sant Hirdaram Medical College of Naturopathy and Yogic Sciences for Women, Bhopal, Madhya Pradesh, India

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Cancer is traditionally approached as a genetic disease, with standard treatments including chemotherapy, radiation, targeted therapy, immunotherapy, and surgery significantly improving survival rates and patient outcomes. However, there is a growing recognition of the need for integrative oncology, which expands cancer management by considering cancer as a metabolic disease. Integrative medicine physicians employ holistic therapies focused on patients' needs, aiming to correct the metabolic imbalances associated with cancer and alleviate cancer-related symptoms. Viewing cancer as a metabolic disease involves addressing factors such as an acidic microenvironment, vitamin C deficiency, mitochondrial dysfunction, reduced intracellular oxygen levels, elevated oxidative stress, dysfunctional autophagy, and psychological stress. This paper presents an overview of the evidence and comprehensive strategies supporting integrative medicine approaches in addressing cancer metabolism in integrative oncology settings. Furthermore, the paper underscores the necessity of integrating different cancer theories-genetic and metabolic-for improved patient outcomes and experiences. By combining these perspectives, integrative oncology offers a more holistic, patient-centered approach to cancer treatment.

Keywords: Metabolism, Warburg theory, Complementary medicine, metabolic disease, Cancer

Received: 26 Jun 2024; Accepted: 29 Aug 2024.

Copyright: © 2024 MK Nair, Silwal, Ramalakshi, Devibala, Saranya, Sivaranjan, R, Palanisamy and Mahalingam. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Pradeep MK Nair, Mirakle Integrated Health Centre, Pollachi, India

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