Ensrud KE, Crandall CJ. Osteoporosis. Ann Intern Med. 2017;167:Itc17–32.

Article  PubMed  Google Scholar 

Rubin MR. Skeletal fragility in diabetes. Ann N Y Acad Sci. 2017;1402:18–30.

Article  PubMed  Google Scholar 

Cai S, Fan J, Zhu L, Ye J, Rao X, Fan C, Zhong Y, Li Y. Bone mineral density and osteoporosis in relation to all-cause and cause-specific mortality in NHANES: a population-based cohort study. Bone. 2020;141:115597.

Article  PubMed  Google Scholar 

Khosla S, Hofbauer LC. Osteoporosis treatment: recent developments and ongoing challenges. Lancet Diabetes Endocrinol. 2017;5:898–907.

Article  PubMed  PubMed Central  Google Scholar 

Wright NC, Looker AC, Saag KG, Curtis JR, Delzell ES, Randall S, Dawson-Hughes B. The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine. J Bone Min Res. 2014;29:2520–6.

Article  Google Scholar 

Afarideh M, Sartori-Valinotti JC, Tollefson MM. Association of Sun-Protective behaviors with Bone Mineral density and osteoporotic bone fractures in US adults. JAMA Dermatol. 2021;157:1437–46.

Article  PubMed  Google Scholar 

Wang G, Fang ZB, Liu DL, Chu SF, Li HL, Zhao HX. Association between caffeine intake and lumbar spine bone mineral density in adults aged 20–49: a cross-sectional study. Front Endocrinol (Lausanne). 2022;13:1008275.

Article  PubMed  Google Scholar 

Tarabeih N, Shalata A, Kalinkovich A, Higla O, Livshits G. Elevated circulating levels of IL-34 are strongly associated with osteoporosis. Arch Osteoporos. 2023;18:132.

Article  PubMed  Google Scholar 

Chen GD, Ding D, Tian HY, Zhu YY, Cao WT, Wang C, Chen YM. Adherence to the 2006 American Heart Association’s Diet and Lifestyle recommendations for cardiovascular disease risk reduction is associated with bone mineral density in older Chinese. Osteoporos Int. 2017;28:1295–303.

Article  PubMed  Google Scholar 

Lee WC, Guntur AR, Long F, Rosen CJ. Energy Metabolism of the osteoblast: implications for osteoporosis. Endocr Rev. 2017;38:255–66.

Article  PubMed  PubMed Central  Google Scholar 

Verheul HM, Hoekman K, Luykx-de Bakker S, Eekman CA, Folman CC, Broxterman HJ, Pinedo HM. Platelet: transporter of vascular endothelial growth factor. Clin Cancer Res. 1997;3:2187–90.

PubMed  Google Scholar 

Potente M, Carmeliet P. The Link between angiogenesis and endothelial metabolism. Annu Rev Physiol. 2017;79:43–66.

Article  PubMed  Google Scholar 

Pennisi P, Signorelli SS, Riccobene S, Celotta G, Di Pino L, La Malfa T, Fiore CE. Low bone density and abnormal bone turnover in patients with atherosclerosis of peripheral vessels. Osteoporos Int. 2004;15:389–95.

Article  PubMed  Google Scholar 

Gawaz M, Langer H, May AE. Platelets in inflammation and atherogenesis. J Clin Invest. 2005;115:3378–84.

Article  PubMed  PubMed Central  Google Scholar 

van der Stoep M, Korporaal SJ, Van Eck M. High-density lipoprotein as a modulator of platelet and coagulation responses. Cardiovasc Res. 2014;103:362–71.

Article  PubMed  Google Scholar 

Grao-Cruces E, Lopez-Enriquez S, Martin ME, Montserrat-de la Paz S. High-density lipoproteins and immune response: a review. Int J Biol Macromol. 2022;195:117–23.

Article  PubMed  Google Scholar 

Zhang J, Hu W, Zou Z, Li Y, Kang F, Li J, Dong S. The role of lipid metabolism in osteoporosis: clinical implication and cellular mechanism. Genes Dis. 2024;11:101122.

Article  PubMed  Google Scholar 

Jialal I, Jialal G, Adams-Huet B. The platelet to high density lipoprotein -cholesterol ratio is a valid biomarker of nascent metabolic syndrome. Diabetes Metab Res Rev. 2021;37:e3403.

Article  PubMed  Google Scholar 

Rendina D, D’Elia L, Evangelista M, De Filippo G, Giaquinto A, Abate V, Barone B, Piccinocchi G, Prezioso D, Strazzullo P. Metabolic syndrome is associated to an increased risk of low bone mineral density in free-living women with suspected osteoporosis. J Endocrinol Invest. 2021;44:1321–6.

Article  PubMed  Google Scholar 

Li H, Li G, Yi M, Zhou J, Deng Y, Huang Y, He S, Meng X, Liu L. Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017–2020) analysis. Front Public Health. 2024;12:1363362.

Article  PubMed  PubMed Central  Google Scholar 

Xie R, Huang X, Liu Q, Liu M. Positive association between high-density lipoprotein cholesterol and bone mineral density in U.S. adults: the NHANES 2011–2018. J Orthop Surg Res. 2022;17:92.

Article  PubMed  PubMed Central  Google Scholar 

Fang W, Peng P, Xiao F, He W, Wei Q, He M. A negative association between total cholesterol and bone mineral density in US adult women. Front Nutr. 2022;9:937352.

Article  PubMed  PubMed Central  Google Scholar 

Zhan H, Liu X, Piao S, Rong X, Guo J. Association between triglyceride-glucose index and bone mineral density in US adults: a cross sectional study. J Orthop Surg Res. 2023;18:810.

Article  PubMed  PubMed Central  Google Scholar 

Xu B, Ma G, Yang L, Chen X, Bian B, Yang B, Zhang D, Qin X, Zhu L, Yin H, et al. Non-linear association of atherogenic index of plasma with bone mineral density a cross-sectional study. Lipids Health Dis. 2024;23:181.

Article  PubMed  PubMed Central  Google Scholar 

Go JH, Song YM, Park JH, Park JY, Choi YH. Association between Serum Cholesterol Level and bone Mineral density at Lumbar Spine and Femur Neck in Postmenopausal Korean Women. Korean J Fam Med. 2012;33:166–73.

Article  PubMed  PubMed Central  Google Scholar 

Wang GX, Li JT, Liu DL, Chu SF, Li HL, Zhao HX, Fang ZB, Xie W. The correlation between high-density lipoprotein cholesterol and bone mineral density in adolescents: a cross-sectional study. Sci Rep. 2023;13:5792.

Article  PubMed  PubMed Central  Google Scholar 

Kristjansdottir HL, Mellström D, Johansson P, Karlsson M, Vandenput L, Lorentzon M, Herlitz H, Ohlsson C, Lerner UH, Lewerin C. High platelet count is associated with low bone mineral density: the MrOS Sweden cohort. Osteoporos Int. 2021;32:865–71.

Article  PubMed  Google Scholar 

Kim J, Kim HS, Lee HS, Kwon YJ. The relationship between platelet count and bone mineral density: results from two independent population-based studies. Arch Osteoporos. 2020;15:43.

Article  PubMed  Google Scholar 

Ma WC, Cheng YC, Lee WJ, Li YH, Lee IT. Circulating platelet concentration is associated with bone mineral density in women. Arch Osteoporos. 2022;17:44.

Article  PubMed  Google Scholar 

Sharif PS, Abdollahi M. The role of platelets in bone remodeling. Inflamm Allergy Drug Targets. 2010;9:393–9.

Article  PubMed  Google Scholar 

van Zeventer IA, de Graaf AO, van der Klauw MM, Vellenga E, van der Reijden BA, Schuringa JJ, Diepstra A, Malcovati L, Jansen JH, Huls G. Peripheral blood cytopenias in the aging general population and risk of incident hematological disease and mortality. Blood Adv. 2021;5:3266–78.

Article  PubMed  PubMed Central  Google Scholar 

Anagnostis P, Karagiannis A, Kakafika AI, Tziomalos K, Athyros VG, Mikhailidis DP. Atherosclerosis and osteoporosis: age-dependent degenerative processes or related entities? Osteoporos Int. 2009;20:197–207.

Article  PubMed  Google Scholar 

Jilka RL. The relevance of mouse models for investigating age-related bone loss in humans. J Gerontol Biol Sci Med Sci. 2013;68:1209–17.

Article  Google Scholar 

Becker DM, Segal J, Vaidya D, Yanek LR, Herrera-Galeano JE, Bray PF, Moy TF, Becker LC, Faraday N. Sex differences in platelet reactivity and response to low-dose aspirin therapy. JAMA. 2006;295:1420–7.

Article