TRanscranial AlterNating current stimulation FOR patients with mild Alzheimer’s Disease (TRANSFORM-AD): a randomized controlled clinical trial

Fernandez-Ruiz A, Oliva A, Soula M, Rocha-Almeida F, Nagy GA, Martin-Vazquez G et al. Gamma rhythm communication between entorhinal cortex and dentate gyrus neuronal assemblies. Science 2021, 372(6537).

Wang DX, Schmitt K, Seger S, Davila CE, Lega BC. Cross-regional phase amplitude coupling supports the encoding of episodic memories. Hippocampus. 2021;31(5):481–92.

Article  PubMed  PubMed Central  Google Scholar 

Lega B, Burke J, Jacobs J, Kahana MJ. Slow-Theta-to-Gamma Phase-Amplitude Coupling in Human Hippocampus supports the formation of New Episodic Memories. Cereb Cortex. 2016;26(1):268–78.

Article  PubMed  Google Scholar 

Goutagny R, Gu N, Cavanagh C, Jackson J, Chabot JG, Quirion R, et al. Alterations in hippocampal network oscillations and theta-gamma coupling arise before Abeta overproduction in a mouse model of Alzheimer’s disease. Eur J Neurosci. 2013;37(12):1896–902.

Article  PubMed  Google Scholar 

Koenig T, Prichep L, Dierks T, Hubl D, Wahlund LO, John ER, et al. Decreased EEG synchronization in Alzheimer’s disease and mild cognitive impairment. Neurobiol Aging. 2005;26(2):165–71.

Article  CAS  PubMed  Google Scholar 

Stam CJ, van Cappellen AM, Pijnenburg YA, Berendse HW, de Munck JC, Scheltens P, et al. Generalized synchronization of MEG recordings in Alzheimer’s Disease: evidence for involvement of the gamma band. J Clin Neurophysiol. 2002;19(6):562–74.

Article  PubMed  Google Scholar 

Mehak SF, Shivakumar AB, Kumari S, Muralidharan B, Gangadharan G. Theta and gamma oscillatory dynamics in mouse models of Alzheimer’s disease: a path to prospective therapeutic intervention. Neurosci Biobehav Rev. 2022;136:104628.

Article  PubMed  Google Scholar 

Grover S, Fayzullina R, Bullard BM, Levina V, Reinhart RMG. A meta-analysis suggests that tACS improves cognition in healthy, aging, and psychiatric populations. Sci Transl Med. 2023;15(697):eabo2044.

Article  PubMed  PubMed Central  Google Scholar 

Manippa V, Palmisano A, Nitsche MA, Filardi M, Vilella D, Logroscino G et al. Cognitive and neuropathophysiological outcomes of Gamma-tACS in Dementia: a systematic review. Neuropsychol Rev 2023.

Sprugnoli G, Munsch F, Cappon D, Paciorek R, Macone J, Connor A, et al. Impact of multisession 40Hz tACS on hippocampal perfusion in patients with Alzheimer’s disease. Alzheimers Res Ther. 2021;13(1):203.

Article  PubMed  PubMed Central  Google Scholar 

Zhou D, Li A, Li X, Zhuang W, Liang Y, Zheng CY, et al. Effects of 40 hz transcranial alternating current stimulation (tACS) on cognitive functions of patients with Alzheimer’s disease: a randomised, double-blind, sham-controlled clinical trial. J Neurol Neurosurg Psychiatry. 2022;93(5):568–70.

Article  PubMed  Google Scholar 

Dhaynaut M, Sprugnoli G, Cappon D, Macone J, Sanchez JS, Normandin MD, et al. Impact of 40 hz transcranial Alternating Current Stimulation on Cerebral Tau Burden in patients with Alzheimer’s Disease: a Case Series. J Alzheimers Dis. 2022;85(4):1667–76.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Louviot S, Tyvaert L, Maillard LG, Colnat-Coulbois S, Dmochowski J, Koessler L. Transcranial Electrical Stimulation generates electric fields in deep human brain structures. Brain Stimul. 2022;15(1):1–12.

Article  PubMed  Google Scholar 

Krause MR, Vieira PG, Csorba BA, Pilly PK, Pack CC. Transcranial alternating current stimulation entrains single-neuron activity in the primate brain. Proc Natl Acad Sci U S A. 2019;116(12):5747–55.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shan Y, Wang H, Yang Y, Wang J, Zhao W, Huang Y et al. Evidence of a large current of transcranial alternating current stimulation directly to deep brain regions. Mol Psychiatry 2023.

Xing Y, Wei P, Wang C, Shan Y, Yu Y, Qiao Y, et al. TRanscranial AlterNating current stimulation FOR patients with mild Alzheimer’s Disease (TRANSFORM-AD study): protocol for a randomized controlled clinical trial. Alzheimers Dement (N Y). 2020;6(1):e12005.

Article  PubMed  Google Scholar 

McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR Jr., Kawas CH, et al. The diagnosis of dementia due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement. 2011;7(3):263–9.

Article  PubMed  Google Scholar 

Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL. A new clinical scale for the staging of dementia. Br J Psychiatry. 1982;140:566–72.

Article  CAS  PubMed  Google Scholar 

Jack CR Jr., Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, et al. NIA-AA Research Framework: toward a biological definition of Alzheimer’s disease. Alzheimers Dement. 2018;14(4):535–62.

Article  PubMed  Google Scholar 

Mathis CA, Wang Y, Holt DP, Huang GF, Debnath ML, Klunk WE. Synthesis and evaluation of 11 C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents. J Med Chem. 2003;46(13):2740–54.

Article  CAS  PubMed  Google Scholar 

Lei D, Mao C, Li J, Huang X, Sha L, Liu C, et al. CSF biomarkers for early-onset Alzheimer’s disease in Chinese population from PUMCH dementia cohort. Front Neurol. 2022;13:1030019.

Article  PubMed  Google Scholar 

Wang H, Wang K, Xue Q, Peng M, Yin L, Gu X, et al. Transcranial alternating current stimulation for treating depression: a randomized controlled trial. Brain. 2022;145(1):83–91.

Article  CAS  PubMed  Google Scholar 

Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer’s disease. Am J Psychiatry. 1984;141(11):1356–64.

Article  CAS  PubMed  Google Scholar 

Folstein MF, Folstein SE, McHugh PR. Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189–98.

Article  CAS  PubMed  Google Scholar 

Nasreddine ZS, Phillips NA, Bedirian V, Charbonneau S, Whitehead V, Collin I, et al. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005;53(4):695–9.

Article  PubMed  Google Scholar 

Maj M, D’Elia L, Satz P, Janssen R, Zaudig M, Uchiyama C, et al. Evaluation of two new neuropsychological tests designed to minimize cultural bias in the assessment of HIV-1 seropositive persons: a WHO study. Arch Clin Neuropsychol. 1993;8(2):123–35.

Article  CAS  PubMed  Google Scholar 

Cummings JL, Mega M, Gray K, Rosenberg-Thompson S, Carusi DA, Gornbein J. The neuropsychiatric inventory: comprehensive assessment of psychopathology in dementia. Neurology. 1994;44(12):2308–14.

Article  CAS  PubMed  Google Scholar 

Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1982;17(1):37–49.

Article  PubMed  Google Scholar 

Tadel F, Baillet S, Mosher JC, Pantazis D, Leahy RM. Brainstorm: a user-friendly application for MEG/EEG analysis. Comput Intell Neurosci. 2011;2011:879716.

Article  PubMed  PubMed Central  Google Scholar 

Gramfort A, Papadopoulo T, Olivi E, Clerc M. OpenMEEG: opensource software for quasistatic bioelectromagnetics. Biomed Eng Online. 2010;9:45.

Article  PubMed  PubMed Central  Google Scholar 

Kybic J, Clerc M, Abboud T, Faugeras O, Keriven R, Papadopoulo T. A common formalism for the integral formulations of the forward EEG problem. IEEE Trans Med Imaging. 2005;24(1):12–28.

Article  PubMed  Google Scholar 

Dale AM, Liu AK, Fischl BR, Buckner RL, Belliveau JW, Lewine JD, et al. Dynamic Stat Parametric Mapp Neuron. 2000;26(1):55–67.

CAS  Google Scholar 

Desikan RS, Segonne F, Fischl B, Quinn BT, Dickerson BC, Blacker D, et al. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. NeuroImage. 2006;31(3):968–80.

Article  PubMed  Google Scholar 

Canolty RT, Edwards E, Dalal SS, Soltani M, Nagarajan SS, Kirsch HE, et al. High gamma power is phase-locked to theta oscillations in human neocortex. Science. 2006;313(5793):1626–8.

Article  CAS  PubMed  PubMe

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