Myocardial Mechanics in Acromegaly: A Meta-Analysis of Echocardiographic Studies

Melmed S, Bronstein MD, Chanson P, Klibanski A, Casanueva FF, Wass JAH, Strasburger CJ, Luger A, Clemmons DR, Giustina A. A Consensus Statement on acromegaly therapeutic outcomes. Nat Rev Endocrinol. 2018;14(9):552–61. https://doi.org/10.1038/s41574-018-0058-5.

Article  PubMed  PubMed Central  Google Scholar 

Rosendal C, Arlien-Søborg MC, Nielsen EH, Andersen MS, Feltoft CL, Kistorp C, Dekkers OM, Jørgensen JOL, Dal J. The changing landscape of acromegaly—an epidemiological perspective. Rev Endocr Metab Disord. 2024;25(4):691–705. https://doi.org/10.1007/s11154-024-09875-z.

Article  PubMed  Google Scholar 

Rosendal C, Arlien-Søborg MC, Nielsen EH, Andersen MS, Feltoft CL, Klose M, Andreassen M, Bruun NH, Jørgensen JOL, Dal J. Changes in acromegaly comorbidities, treatment, and outcome over three decades: a nationwide cohort study. Front Endocrinol (Lausanne). 2024;4(15):1380436. https://doi.org/10.3389/fendo.2024.1380436.

Article  Google Scholar 

Sharma MD, Nguyen AV, Brown S, Robbins RJ. Cardiovascular disease in acromegaly. Methodist Debakey Cardiovasc J. 2017;13:64–6. https://doi.org/10.14797/mdcj-13-2-64.

Article  PubMed  PubMed Central  Google Scholar 

Bolfi F, Neves AF, Boguszewski CL, Nunes-Nogueira VS. Mortality in acromegaly decreased in the last decade: a systematic review and meta-analysis. Eur J Endocrinol. 2018;179:59–71. https://doi.org/10.1530/EJE-18-0255.

Article  CAS  PubMed  Google Scholar 

Arosio M, Sciannameo V, Contarino A, Berchialla P, Puglisi S, Pesatori AC, Ferrante E, Filopanti M, Pivonello R, Dassie F, Rochira V, Cannavò S, De Menis E, Pigliaru F, Grottoli S, Cambria V, Faustini-Fustini M, Montini M, Peri A, Ceccato F, Puxeddu E, Borretta G, Bondanelli M, Ferone D, Colao A, Terzolo M, Reimondo G. Disease control of acromegaly does not prevent excess mortality in the long term: results of a nationwide survey in Italy. J Endocrinol Invest. 2024;47:1457–65. https://doi.org/10.1007/s40618-023-02257-3.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wolf P, Maione L, Kamenický P, Chanson P. Acromegalic cardiomyopathy: an entity on its own? The effects of GH and IGF-I excess and treatment on cardiovascular risk factors. Arch Med Res. 2023;54(8): 102921. https://doi.org/10.1016/j.arcmed.2023.102921.

Article  CAS  PubMed  Google Scholar 

Kamenický P, Maione L, Chanson P. Cardiovascular complications of acromegaly. Ann Endocrinol (Paris). 2021;82:206–9. https://doi.org/10.1016/j.ando.2020.03.010.

Article  PubMed  Google Scholar 

Hong S, Kim KS, Han K, Park CY. Acromegaly and cardiovascular outcomes: a cohort study. Eur Heart J. 2022;43:1491–9. https://doi.org/10.1093/eurheartj/ehab822.

Article  PubMed  Google Scholar 

Wolf P, Bouazizi K, Kachenoura N, Piedvache C, Gallo A, Salenave S, Maione L, Young J, Prigent M, Lecoq AL, Kuhn E, Agostini H, Trabado S, Redheuil A, Chanson P, Kamenický P. Increase in intracellular and extracellular myocardial mass in patients with acromegaly: a cardiac magnetic resonance imaging study. Eur J Endocrinol. 2023;189:199–207. https://doi.org/10.1093/ejendo/lvad105.

Article  PubMed  Google Scholar 

Hinojosa-Amaya JM, Varlamov EV, Yedinak CG, Cetas JS, McCartney S, Banskota S, Fleseriu M. Echocardiographic findings in acromegaly: prevalence of concentric left ventricular remodeling in a large single-center cohort. J Endocrinol Invest. 2021;44:2665–74. https://doi.org/10.1007/s40618-021-01579-4.

Article  CAS  PubMed  Google Scholar 

Guo X, Fu H, Pang H, Xing B. Risk of left ventricular hypertrophy and diastolic and systolic dysfunction in acromegaly: a meta-analysis. J Clin Neurosci. 2018;48:28–33. https://doi.org/10.1016/j.jocn.2017.10.067.

Article  PubMed  Google Scholar 

Colao A, Grasso LFS, Di Somma C, Pivonello R. Acromegaly and heart failure. Heart Fail Clin. 2019;15:399–408. https://doi.org/10.1016/j.hfc.2019.03.001.

Article  PubMed  Google Scholar 

Guo X, Cao J, Liu P, Cao Y, Li X, Gao L, Wang Z, Fang L, Jin Z, Wang Y, Xing B. Cardiac abnormalities in acromegaly patients: a cardiac magnetic resonance study. Int J Endocrinol. 2020;14(2020):2018464. https://doi.org/10.1155/2020/2018464.

Article  CAS  Google Scholar 

De Alcubierre D, Feola T, Cozzolino A, Pofi R, Galea N, Catalano C, Auriemma RS, Pirchio R, Pivonello R, Isidori AM, Giannetta E. The spectrum of cardiac abnormalities in patients with acromegaly: results from a case-control cardiac magnetic resonance study. Pituitary. 2024;27(4):416–27. https://doi.org/10.1007/s11102-024-01403-1.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Potter E, Marwick TH. Assessment of left ventricular function by echocardiography: the case for routinely adding global longitudinal strain to ejection fraction. JACC Cardiovasc Imaging. 2018;11:260–74. https://doi.org/10.1016/j.jcmg.2017.11.017.

Article  PubMed  Google Scholar 

Kuznetsova T, Cauwenberghs T, Knez J, Yang WY, Herbots L, D’hooge J, Haddad F, Thijs L, Voigt JU, Staessen JA. Additive prognostic value of left ventricular systolic dysfunction in a population-based cohort. Circ Cardiovasc Imaging. 2016;9: e004661. https://doi.org/10.1161/CIRCIMAGING.116.004661.

Article  PubMed  Google Scholar 

Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339:2535. https://doi.org/10.1136/bmj.b2535.

Article  Google Scholar 

Volschan ICM, Kasuki L, Silva CMS, Alcantara ML, Saraiva RM, Xavier SS, Gadelha MR. Two-dimensional speckle tracking echocardiography demonstrates no effect of active acromegaly on left ventricular strain. Pituitary. 2017;20:349–57. https://doi.org/10.1007/s11102-017-0795-9.

Article  CAS  PubMed  Google Scholar 

Popielarz-Grygalewicz A, Gąsior JS, Konwicka A, Grygalewicz P, Stelmachowska-Banaś M, Zgliczyński W, Dąbrowski M. Heart in acromegaly: the echocardiographic characteristics of patients diagnosed with acromegaly in various stages of the disease. Int J Endocrinol. 2018;2018:1–7. https://doi.org/10.1155/2018/6935054.

Article  Google Scholar 

Kormányos Á, Domsik P, Kalapos A, Gyenes N, Valkusz Z, Lengyel C, Forster T, Nemes A. Active acromegaly is associated with enhanced left ventricular contractility: results from the three-dimensional speckle-tracking echocardiographic MAGYAR-Path Study. Rev Port Cardiol. 2020;39:189–96. https://doi.org/10.1016/j.repc.2019.08.010.

Article  PubMed  Google Scholar 

Uziȩbło-Życzkowska B, Jurek A, Witek P, Zieliński G, Gielerak G, Krzesiński P. Left heart dysfunction in acromegaly revealed by novel echocardiographic methods. Front Endocrinol. 2020;11:418. https://doi.org/10.3389/fendo.2020.00418.

Article  Google Scholar 

Gadelha P, Santos ECL, Castillo J, Vilar L. Subclinical ventricular dysfunction in long-term acromegaly assessed by speckle-tracking echocardiography. Front Endocrinol. 2022;13: 812964. https://doi.org/10.3389/fendo.2022.812964.

Article  Google Scholar 

Koca H, Koc M, Sumbul HE, Icen YK, Gulumsek E, Koca F, Ozturk HA, Baykan AO, Kaypakli O. Subclinical left atrial and ventricular dysfunction in acromegaly patients: a speckle tracking echocardiography study. Arq Bras Cardiol. 2022;118:634–45. https://doi.org/10.36660/abc.20201174.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Firlatan B, Karakulak UN, Hekimsoy V, Iremli BG, Lay I, Yuce D, Dagdelen S, Kabakci G, Erbas T. Evaluation of the relation between subclinical systolic dysfunction defined by four-dimensional speckle-tracking echocardiography and growth differentiation factor-15 levels in patients with acromegaly. Hormones. 2024. https://doi.org/10.1007/s42000-024-00558-7.

Article  PubMed  Google Scholar 

Bogazzi F, Lombardi M, Strata E, Aquaro G, Di Bello V, Cosci C, Sardella C, Talini E, Martino E. High prevalence of cardiac hypertrophy without detectable signs of fibrosis in patients with untreated active acromegaly: an in vivo study using magnetic resonance imaging. Clin Endocrinol (Oxf). 2008;68:361–8. https://doi.org/10.1111/j.1365-2265.2007.03047.x.

Article  PubMed  Google Scholar 

Gouya H, Vignaux O, Le Roux P, Chanson P, Bertherat J, Bertagna X, Legmann P. Rapidly reversible myocardial edema in patients with acromegaly: assessment with ultrafast T2 mapping in a single-breath-hold MRI sequence. AJR Am J Roentgenol. 2008;190:1576–82. https://doi.org/10.2214/AJR.07.2031.

Article  PubMed  Google Scholar 

Cansu GB, Yılmaz N, Yanıkoğlu A, Özdem S, Yıldırım AB, Süleymanlar G, Altunbaş HA. Assessment of diastolic dysfunction, arterial stiffness, and carotid intima-media thickness in patients with acromegaly. Endocr Pract. 2017;23:536–45. https://doi.org/10.4158/EP161637.

Article  PubMed  Google Scholar 

Mehrzad R, Rajab M, Spodick DH. The three integrated phases of left atrial macrophysiology and the

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