Phillips AA, Krassioukov AV, Ainslie PN, Warburton DE. Baroreflex function after spinal cord injury. J Neurotrauma. 2012;29:2431–45.

Article  PubMed  Google Scholar 

Cragg JJ, Noonan VK, Krassioukov A, Borisoff J. Cardiovascular disease and spinal cord injury: results from a national population health survey. Neurology. 2013;81:723–8.

Article  PubMed  PubMed Central  Google Scholar 

Laterza MC, de Matos LD, Trombetta IC, Braga AM, Roveda F, Alves MJ, et al. Exercise training restores baroreflex sensitivity in never-treated hypertensive patients. Hypertension. 2007;49:1298–306.

Article  PubMed  Google Scholar 

Monahan KD, Dinenno FA, Tanaka H, Clevenger CM, DeSouza CA, Seals DR. Regular aerobic exercise modulates age-associated declines in cardiovagal baroreflex sensitivity in healthy men. J Physiol. 2000;529:263–71.

Article  PubMed  PubMed Central  Google Scholar 

Madden KM, Lockhart C, Potter TF, Cuff D. Aerobic training restores arterial baroreflex sensitivity in older adults with type 2 diabetes, hypertension, and hypercholesterolemia. Clin J Sport Med. 2010;20:312–7.

Article  PubMed  PubMed Central  Google Scholar 

Martin Ginis KA, van der Scheer JW, Latimer-Cheung AE, Barrow A, Bourne C, Carruthers P, et al. Evidence-based scientific exercise guidelines for adults with spinal cord injury: an update and a new guideline. Spinal Cord. 2018;56:308–21.

Article  PubMed  Google Scholar 

Chiou SY, Clarke E, Lam C, Harvey T, Nightingale TE. Effects of arm-crank exercise on fitness and health in adults with chronic spinal cord injury: a systematic review. Front Physiol. 2022;13:831372.

Article  PubMed  PubMed Central  Google Scholar 

Nightingale TE, Walhin JP, Thompson D, Bilzon JLJ. Impact of exercise on cardiometabolic component risks in spinal cord-injured humans. Med Sci Sports Exerc. 2017;49:2469–77.

Article  PubMed  PubMed Central  Google Scholar 

Solinsky R, Draghici A, Hamner JW, Goldstein R, Taylor JA. High-intensity, whole-body exercise improves blood pressure control in individuals with spinal cord injury: a prospective randomized controlled trial. PLoS ONE. 2021;16:e0247576.

Article  PubMed  PubMed Central  Google Scholar 

Ditor DS, Macdonald MJ, Kamath MV, Bugaresti J, Adams M, McCartney N, et al. The effects of body-weight supported treadmill training on cardiovascular regulation in individuals with motor-complete SCI. Spinal Cord. 2005;43:664–73.

Article  PubMed  Google Scholar 

Ditor DS, Kamath MV, MacDonald MJ, Bugaresti J, McCartney N, Hicks AL. Effects of body weight-supported treadmill training on heart rate variability and blood pressure variability in individuals with spinal cord injury. J Appl Physiol. 2005;98:1519–25.

Article  PubMed  Google Scholar 

Claydon VE, Steeves JD, Krassioukov A. Orthostatic hypotension following spinal cord injury: understanding clinical pathophysiology. Spinal Cord. 2006;44:341–51.

Article  PubMed  Google Scholar 

Carter JB, Banister EW, Blaber AP. Effect of endurance exercise on autonomic control of heart rate. Sports Med. 2003;33:33–46.

Article  PubMed  Google Scholar 

Xu D, Wang H, Chen S, Ross S, Liu H, Olivencia-Yurvati A, et al. Aerobic exercise training improves orthostatic tolerance in aging humans. Med Sci Sports Exerc. 2017;49:728–35.

Article  PubMed  Google Scholar 

Krassioukov AV, Currie KD, Hubli M, Nightingale TE, Alrashidi AA, Ramer L, et al. Effects of exercise interventions on cardiovascular health in individuals with chronic, motor complete spinal cord injury: protocol for a randomised controlled trial [Cardiovascular Health/Outcomes: Improvements Created by Exercise and education in SCI (CHOICES) Study]. BMJ Open. 2019;9:e023540.

Article  PubMed  PubMed Central  Google Scholar 

Kirshblum SC, Burns SP, Biering-Sorensen F, Donovan W, Graves DE, Jha A, et al. International standards for neurological classification of spinal cord injury (revised 2011). J Spinal Cord Med. 2011;34:535–46.

Article  PubMed  PubMed Central  Google Scholar 

Reference Values for Arterial Stiffness C. Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values’. Eur Heart J. 2010;31:2338–50.

Harkema SJ, Ferreira CK, van den Brand RJ, Krassioukov AV. Improvements in orthostatic instability with stand locomotor training in individuals with spinal cord injury. J Neurotrauma. 2008;25:1467–75.

Article  PubMed  PubMed Central  Google Scholar 

Alrashidi AA, Nightingale TE, Currie KD, Hubli M, MacDonald MJ, Hicks AL, et al. Exercise improves cardiorespiratory fitness, but not arterial health, after spinal cord injury: the CHOICES trial. J Neurotrauma. 2021;38:3020–9.

Article  PubMed  Google Scholar 

Currie KD, Wong SC, Warburton DE, Krassioukov AV. Reliability of the sit-up test in individuals with spinal cord injury. J Spinal Cord Med. 2015;38:563–6.

Dorey TW, O’Brien MW, Robinson SA, Kimmerly DS. Knee-high compression socks minimize head-up tilt-induced cerebral and cardiovascular responses following dynamic exercise. Scand J Med Sci Sports. 2018;28:1766–74.

Article  PubMed  Google Scholar 

Harms MP, Wesseling KH, Pott F, Jenstrup M, Van Goudoever J, Secher NH, et al. Continuous stroke volume monitoring by modelling flow from non-invasive measurement of arterial pressure in humans under orthostatic stress. Clin Sci. 1999;97:291–301.

Article  Google Scholar 

Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 1996;93:1043–65.

Parati G, Saul JP, Di Rienzo M, Mancia G. Spectral analysis of blood pressure and heart rate variability in evaluating cardiovascular regulation. A critical appraisal. Hypertension. 1995;25:1276–86.

Article  PubMed  Google Scholar 

Dorey TW, O’Brien MW, Kimmerly DS. The influence of aerobic fitness on electrocardiographic and heart rate variability parameters in young and older adults. Auton Neurosci. 2019;217:66–70.

Article  PubMed  Google Scholar 

Dorey TW, Walter M, Krassioukov AV. Reduced reflex autonomic responses following intradetrusor OnabotulinumtoxinA Injections: a pre-/post-study in individuals with cervical and upper thoracic spinal cord injury. Front Physiol. 2021;12:796277.

Article  PubMed  PubMed Central  Google Scholar 

Shaffer F, Ginsberg JP. An overview of heart rate variability metrics and norms. Front Public Health. 2017;5:258.

Article  PubMed  PubMed Central  Google Scholar 

Zhang R, Iwasaki K, Zuckerman JH, Behbehani K, Crandall CG, Levine BD. Mechanism of blood pressure and R-R variability: insights from ganglion blockade in humans. J Physiol. 2002;543:337–48.

Article  PubMed  PubMed Central  Google Scholar 

Parati G, Di Rienzo M, Mancia G. How to measure baroreflex sensitivity: from the cardiovascular laboratory to daily life. J Hypertens. 2000;18:7–19.

Article  PubMed  Google Scholar 

Parlow J, Viale JP, Annat G, Hughson R, Quintin L. Spontaneous cardiac baroreflex in humans. Comparison with drug-induced responses. Hypertension. 1995;25:1058–68.

Article  PubMed  Google Scholar 

O’Brien MW, Johns JA, Dorey TW, Frayne RJ, Fowles JR, Mekary S, et al. Meeting international aerobic physical activity guidelines is associated with enhanced cardiovagal baroreflex sensitivity in healthy older adults. Clin Auton Res. 2020;30:139–48.

Article  PubMed  Google Scholar 

Lakens D. Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs. Front Psychol. 2013;4:863.

Article  PubMed  PubMed Central  Google Scholar 

La Rovere MT, Pinna GD. Beneficial effects of physical activity on baroreflex control in the elderly. Ann Noninvasive Electrocardiol. 2014;19:303–10.

Article  PubMed  PubMed Central  Google Scholar 

Winker R, Barth A, Bidmon D, Ponocny I, Weber M, Mayr O, et al. Endurance exercise training in orthostatic intolerance: a randomized, controlled trial. Hypertension. 2005;45:391–8.

Article  PubMed  Google Scholar 

Ray CA, Hume KM. Sympathetic neural adaptations to exercise training in humans: insights from microneurography. Med Sci Sports Exerc. 1998;30:387–91.

Article  PubMed