Administration of Aripiprazole Alleviates Memory Impairment and Restores Damaged Glutamatergic System in 5xFAD Mice

(2020) 2020 Alzheimer's disease facts and figures. Alzheimers Dement

Jack CR Jr, Knopman DS, Jagust WJ et al (2013) Tracking pathophysiological processes in Alzheimer’s disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol 12:207–216

Article  CAS  PubMed  PubMed Central  Google Scholar 

Murray PS, Kumar S, Demichele-Sweet MA, Sweet RA (2014) Psychosis in Alzheimer’s disease. Biol Psychiatry 75:542–552

Article  PubMed  Google Scholar 

Sweet RA, Nimgaonkar VL, Devlin B, Jeste DV (2003) Psychotic symptoms in Alzheimer disease: evidence for a distinct phenotype. Mol Psychiatry 8:383–392

Article  CAS  PubMed  Google Scholar 

Oakley H, Cole SL, Logan S et al (2006) Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer’s Disease Mutations: Potential Factors in Amyloid Plaque Formation. J Neurosci 26:10129–10140

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tuplin EW, Holahan MR (2017) Aripiprazole, A Drug that Displays Partial Agonism and Functional Selectivity. Curr Neuropharmacol 15:1192–1207

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pae CU (2009) A review of the safety and tolerability of aripiprazole. Expert Opin Drug Saf 8:373–386

Article  CAS  PubMed  Google Scholar 

Blier P, Blondeau C (2011) Neurobiological bases and clinical aspects of the use of aripiprazole in treatment-resistant major depressive disorder. J Affect Disord 128(Suppl 1):S3-10

Article  CAS  PubMed  Google Scholar 

Croxtall JD (2012) Aripiprazole: a review of its use in the management of schizophrenia in adults. CNS Drugs 26:155–183

Article  CAS  PubMed  Google Scholar 

McIntyre RS, Yoon J, Jerrell JM, Liauw SS (2011) Aripiprazole for the maintenance treatment of bipolar disorder: a review of available evidence. Neuropsychiatr Dis Treat 7:319–323

Article  CAS  PubMed  PubMed Central  Google Scholar 

Danbolt NC (2001) Glutamate uptake. Prog Neurobiol 65:1–105

Article  CAS  PubMed  Google Scholar 

Hassel B, Dingledine R (2012) Glutamatae and glutamate receptors. In Brady BT et al (eds.) Basic neurochemistry: principles of molecular, cellular, and medical neurobiology, 8th edn. Elsevier, pp 342–366

Gasiorowska A, Wydrych M, Drapich P et al (2021) The Biology and Pathobiology of Glutamatergic, Cholinergic, and Dopaminergic Signaling in the Aging Brain. Front Aging Neurosci 13:654931

Article  CAS  PubMed  PubMed Central  Google Scholar 

Terry RD, Peck A, DeTeresa R, Schechter R, Horoupian DS (1981) Some morphometric aspects of the brain in senile dementia of the Alzheimer type. Ann Neurol 10:184–192

Article  CAS  PubMed  Google Scholar 

Greenamyre JT, Penney JB, Young AB, D’Amato CJ, Hicks SP, Shoulson I (1985) Alterations in L-glutamate binding in Alzheimer’s and Huntington’s diseases. Science 227:1496–1499

Article  CAS  PubMed  Google Scholar 

Mrdjen D, Fox EJ, Bukhari SA, Montine KS, Bendall SC, Montine TJ (2019) The basis of cellular and regional vulnerability in Alzheimer’s disease. Acta Neuropathol 138:729–749

Article  PubMed  PubMed Central  Google Scholar 

Vogel-Ciernia A, Wood MA (2014) Examining object location and object recognition memory in mice. Curr Protoc Neurosci 69:8–31

Article  PubMed Central  Google Scholar 

Monastero R, Mangialasche F, Camarda C, Ercolani S, Camarda R (2009) A systematic review of neuropsychiatric symptoms in mild cognitive impairment. J Alzheimers Dis 18:11–30

Article  PubMed  Google Scholar 

Wojtunik-Kulesza K, Rudkowska M, Orzel-Sajdlowska A (2023) Aducanumab-Hope or Disappointment for Alzheimer’s Disease. Int J Mol Sci 24(5):4367

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hansen RA, Gartlehner G, Webb AP, Morgan LC, Moore CG, Jonas DE (2008) Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer’s disease: a systematic review and meta-analysis. Clin Interv Aging 3:211–225

CAS  PubMed  PubMed Central  Google Scholar 

Kurkinen M (2023) Lecanemab (Leqembi) is not the right drug for patients with Alzheimer’s disease. Adv Clin Exp Med 32:943–947

Article  PubMed  Google Scholar 

Folch J, Busquets O, Ettcheto M et al (2018) Memantine for the Treatment of Dementia: A Review on its Current and Future Applications. J Alzheimers Dis 62:1223–1240

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mintzer JE, Tune LE, Breder CD et al (2007) Aripiprazole for the treatment of psychoses in institutionalized patients with Alzheimer dementia: a multicenter, randomized, double-blind, placebo-controlled assessment of three fixed doses. Am J Geriatr Psychiatry 15:918–931

Article  PubMed  Google Scholar 

Jeong YJ, Son Y, Park HJ et al (2021) Therapeutic Effects of Aripiprazole in the 5xFAD Alzheimer’s Disease Mouse Model. Int J Mol Sci 22(17):9374

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gupta T, Singh V, Hefnawy M et al (2023) Ameliorating the Role of Aripiprazole in Memory Deficits Induced by Intracerebroventricular Streptozotocin-Induced Dementia of Alzheimer’s Type. ACS Omega 8:25295–25302

Article  CAS  PubMed  PubMed Central  Google Scholar 

Farlow MR, Shamliyan TA (2017) Benefits and harms of atypical antipsychotics for agitation in adults with dementia. Eur Neuropsychopharmacol 27:217–231

Article  CAS  PubMed  Google Scholar 

Oh SJ, Lee HJ, Jeong YJ et al (2020) Evaluation of the neuroprotective effect of taurine in Alzheimer’s disease using functional molecular imaging. Sci Rep 10:15551

Article  CAS  PubMed  PubMed Central  Google Scholar 

Son Y, Jeong YJ, Shin NR et al (2020) Inhibition of Colony-Stimulating Factor 1 Receptor by PLX3397 Prevents Amyloid Beta Pathology and Rescues Dopaminergic Signaling in Aging 5xFAD Mice. Int J Mol Sci 21(15):5553

Article  CAS  PubMed  PubMed Central  Google Scholar 

留言 (0)

沒有登入
gif