Inulin supplementation in pediatric obesity management: a critical appraisal of efficacy and limitations

Visuthranukul C, Sriswasdi S, Tepaamorndech S, Chamni S, Leelahavanichkul A, Joyjinda Y, et al. Enhancing gut microbiota and microbial function with inulin supplementation in children with obesity. Int J Obes (Lond). 2024. https://doi.org/10.1038/s41366-024-01590-8.

Aron-Wisnewsky J, Warmbrunn MV, Nieuwdorp M, Clément K. Metabolism and metabolic disorders and the microbiome: the intestinal microbiota associated with obesity, lipid metabolism, and metabolic health-pathophysiology and therapeutic strategies. Gastroenterology. 2021;160:573–99. https://doi.org/10.1053/j.gastro.2020.10.057

Article  CAS  PubMed  Google Scholar 

Bouter KE, van Raalte DH, Groen AK, Nieuwdorp M. Role of the gut microbiome in the pathogenesis of obesity and obesity-related metabolic dysfunction. Gastroenterology. 2017;152:1671–8. https://doi.org/10.1053/j.gastro.2016.12.048

Article  CAS  PubMed  Google Scholar 

Drabińska N, Jarocka-Cyrta E, Markiewicz LH, Krupa-Kozak U. The effect of oligofructose-enriched inulin on faecal bacterial counts and microbiota-associated characteristics in celiac disease children following a gluten-free diet: results of a randomized, placebo-controlled trial. Nutrients. 2018;10:201. https://doi.org/10.3390/nu10020201

Article  CAS  PubMed  PubMed Central  Google Scholar 

Parnell JA, Reimer RA. Prebiotic fibres dose-dependently increase satiety hormones and alter Bacteroidetes and Firmicutes in lean and obese JCR:LA-cp rats. Br J Nutr. 2012;107:601–13. https://doi.org/10.1017/s0007114511003163

Article  CAS  PubMed  Google Scholar 

Liber A, Szajewska H. Effect of oligofructose supplementation on body weight in overweight and obese children: a randomised, double-blind, placebo-controlled trial. Br J Nutr. 2014;112:2068–74. https://doi.org/10.1017/s0007114514003110

Article  CAS  PubMed  Google Scholar 

Morales P, Fujio S, Navarrete P, Ugalde JA, Magne F, Carrasco-Pozo C, et al. Impact of dietary lipids on colonic function and microbiota: an experimental approach involving orlistat-induced fat malabsorption in human volunteers. Clin Transl Gastroenterol. 2016;7:e161. https://doi.org/10.1038/ctg.2016.20

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sowah SA, Riedl L, Damms-Machado A, Johnson TS, Schübel R, Graf M, et al. Effects of weight-loss interventions on short-chain fatty acid concentrations in blood and feces of adults: a systematic review. Adv Nutr. 2019;10:673–84. https://doi.org/10.1093/advances/nmy125

Article  PubMed  PubMed Central  Google Scholar 

留言 (0)

沒有登入
gif