Gallo EF, Posner J (2016) Moving towards causality in attention-deficit hyperactivity disorder: overview of neural and genetic mechanisms. Lancet Psychiatry 3:555–567

Article  PubMed  PubMed Central  Google Scholar 

Sharma A, Couture J (2014) A review of the pathophysiology, etiology, and treatment of attention-deficit hyperactivity disorder (ADHD). Ann Pharmacother 48:209–225

Article  PubMed  Google Scholar 

Thomas R, Sanders S, Doust J, Beller E, Glasziou P (2015) Prevalence of attention-deficit/hyperactivity disorder: a systematic review and meta-analysis. Pediatrics 135:e994–1001

Article  PubMed  Google Scholar 

Messent P (2013) DSM-5. Clin Child Psychol Psychiatry 18:479–482

PubMed  Google Scholar 

Childress AC, Berry SA (2012) Pharmacotherapy of attention-deficit hyperactivity disorder in adolescents. Drugs 72:309–325

Article  CAS  PubMed  Google Scholar 

Klein RG, Mannuzza S, Olazagasti MA, Roizen E, Hutchison JA, Lashua EC, Castellanos FX (2012) Clinical and functional outcome of childhood attention-deficit/hyperactivity disorder 33 years later. Arch Gen Psychiatry 69:1295–1303

Article  PubMed  PubMed Central  Google Scholar 

Spencer TJ, Biederman J, Mick E (2007) Attention-deficit/hyperactivity disorder: diagnosis, lifespan, comorbidities, and neurobiology. J Pediatr Psychol 32:631–642

Article  PubMed  Google Scholar 

O’Neill S, Rajendran K, Mahbubani SM, Halperin JM (2017) Preschool predictors of ADHD symptoms and impairment during childhood and adolescence. Curr Psychiatry Rep 19:95

Article  PubMed  PubMed Central  Google Scholar 

Gau SS, Lin YJ, Shang CY, Liu SK, Chiu YN, Soong WT (2010) Emotional/behavioral problems and functional impairment in clinic- and community-based children with attention-deficit/hyperactivity disorder in Taiwan. J Abnorm Child Psychol 38:521–532

Article  PubMed  Google Scholar 

Gjervan B, Torgersen T, Nordahl HM, Rasmussen K (2012) Functional impairment and occupational outcome in adults with ADHD. J Atten Disord 16:544–552

Article  PubMed  Google Scholar 

Chhibber A, Watanabe AH, Chaisai C, Veettil SK, Chaiyakunapruk N (2021) Global Economic Burden of Attention-Deficit/Hyperactivity disorder: a systematic review. PharmacoEconomics 39:399–420

Article  PubMed  Google Scholar 

Chang Z, Lichtenstein P, Asherson PJ, Larsson H (2013) Developmental twin study of attention problems: high heritabilities throughout development. JAMA Psychiatry 70:311–318

Article  PubMed  Google Scholar 

Faraone SV, Perlis RH, Doyle AE, Smoller JW, Goralnick JJ, Holmgren MA, Sklar P (2005) Molecular genetics of attention-deficit/hyperactivity disorder. Biol Psychiatry 57:1313–1323

Article  CAS  PubMed  Google Scholar 

Agency for Toxic Substances and Disease Registry (2022) ATSDR’s substance priority list. https://www.atsdr.cdc.gov/spl/. Accessed 5 March 2024

Bjørklund G, Chartrand MS, Aaseth J (2017) Manganese exposure and neurotoxic effects in children. Environ Res 155:380–384

Article  PubMed  Google Scholar 

Al Osman M, Yang F, Massey IY (2019) Exposure routes and health effects of heavy metals on children. Biometals 32:563–573

Article  CAS  PubMed  Google Scholar 

He B, Wang Y, Li S, Zhao Y, Ma X, Wang W, Li X, Zhang Y (2021) A cross-sectional survey of preschool children: exploring heavy metal exposure, neurotransmitters, and neurobehavioural relationships and mediation effects. Ecotoxicol Environ Saf 220:112391

Article  CAS  PubMed  Google Scholar 

Dórea JG (2019) Environmental exposure to low-level lead (Pb) co-occurring with other neurotoxicants in early life and neurodevelopment of children. Environ Res 177:108641

Article  PubMed  Google Scholar 

Boucher O, Jacobson SW, Plusquellec P, Dewailly E, Ayotte P, Forget-Dubois N, Jacobson JL, Muckle G (2012) Prenatal methylmercury, postnatal lead exposure, and evidence of attention deficit/hyperactivity disorder among Inuit children in Arctic Québec. Environ Health Perspect 120:1456–1461

Article  CAS  PubMed  PubMed Central  Google Scholar 

Renzetti S, Cagna G, Calza S, Conversano M, Fedrighi C, Forte G, Giorgino A, Guazzetti S, Majorani C, Oppini M, Peli M, Petrucci F, Pino A, Placidi D, Senofonte O, Zoni S, Alimonti A, Lucchini RG (2021) The effects of the exposure to neurotoxic elements on Italian schoolchildren behavior. Sci Rep 11:9898

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wright RO, Amarasiriwardena C, Woolf AD, Jim R, Bellinger DC (2006) Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site. Neurotoxicology 27:210–216

Article  CAS  PubMed  Google Scholar 

Khan K, Factor-Litvak P, Wasserman GA, Liu X, Ahmed E, Parvez F, Slavkovich V, Levy D, Mey J, van Geen A, Graziano JH (2011) Manganese exposure from drinking water and children’s classroom behavior in Bangladesh. Environ Health Perspect 119:1501–1506

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bao QS, Lu CY, Song H, Wang M, Ling W, Chen WQ, Deng XQ, Hao YT, Rao S (2009) Behavioural development of school-aged children who live around a multi-metal sulphide mine in Guangdong province, China: a cross-sectional study. BMC Public Health 9:217

Article  PubMed  PubMed Central  Google Scholar 

Goodlad JK, Marcus DK, Fulton JJ (2013) Lead and Attention-Deficit/Hyperactivity disorder (ADHD) symptoms: a meta-analysis. Clin Psychol Rev 33:417–425

Article  PubMed  Google Scholar 

Cheuk DK, Wong V (2006) Attention-deficit hyperactivity disorder and blood mercury level: a case-control study in Chinese children. Neuropediatrics 37:234–240

Article  CAS  PubMed  Google Scholar 

Rodríguez-Barranco M, Lacasaña M, Aguilar-Garduño C, Alguacil J, Gil F, González-Alzaga B, Rojas-García A (2013) Association of arsenic, cadmium and manganese exposure with neurodevelopment and behavioural disorders in children: a systematic review and meta-analysis. Sci Total Environ 454–455:562–577

Article  PubMed  Google Scholar 

Roy A, Kordas K, Lopez P, Rosado JL, Cebrian ME, Vargas GG, Ronquillo D, Stoltzfus RJ (2011) Association between arsenic exposure and behavior among first-graders from Torreón, Mexico. Environ Res 111:670–676

Article  CAS  PubMed  Google Scholar 

Lee MJ, Chou MC, Chou WJ, Huang CW, Kuo HC, Lee SY, Wang LJ (2018) Heavy Metals’ Effect on Susceptibility to Attention-Deficit/Hyperactivity Disorder: Implication of Lead, Cadmium, and Antimony. Int J Environ Res Public Health 15

Muñoz MP, Rubilar P, Valdés M, Muñoz-Quezada MT, Gómez A, Saavedra M, Iglesias V (2020) Attention deficit hyperactivity disorder and its association with heavy metals in children from northern Chile. Int J Hyg Environ Health 226:113483

Article  PubMed  Google Scholar 

Ciesielski T, Weuve J, Bellinger DC, Schwartz J, Lanphear B, Wright RO (2012) Cadmium exposure and neurodevelopmental outcomes in U.S. children. Environ Health Perspect 120:758–763

Article  CAS  PubMed  PubMed Central  Google Scholar 

Szkup-Jabłońska M, Karakiewicz B, Grochans E, Jurczak A, Nowak-Starz G, Rotter I, Prokopowicz A (2012) Effects of blood lead and cadmium levels on the functioning of children with behaviour disorders in the family environment. Ann Agric Environ Med 19:241–246

PubMed  Google Scholar 

Rodríguez-Barranco M, Gil F, Hernández AF, Alguacil J, Lorca A, Mendoza R, Gómez I, Molina-Villalba I, González-Alzaga B, Aguilar-Garduño C, Rohlman DS, Lacasaña M (2016) Postnatal arsenic exposure and attention impairment in school children. Cortex 74:370–382

Article  PubMed  Google Scholar 

Yousef S, Adem A, Zoubeidi T, Kosanovic M, Mabrouk AA, Eapen V (2011) Attention deficit hyperactivity disorder and environmental toxic metal exposure in the United Arab Emirates. J Trop Pediatr 57:457–460

Article  PubMed