Higher-order interactions between hippocampal CA1 neurons are disrupted in amnestic mice

Tulving, E. in Organization of Memory (eds Tulving, E. & Donaldson, W.) 381–403 (Academic Press, 1972).

O’Keefe, J. & Dostrovsky, J. The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat. Brain Res. 34, 171–175 (1971).

Article  PubMed  Google Scholar 

Buzsáki, G. Neural syntax: cell assemblies, synapsembles, and readers. Neuron 68, 362–385 (2010).

Article  PubMed  PubMed Central  Google Scholar 

Eichenbaum, H. Prefrontal–hippocampal interactions in episodic memory. Nat. Rev. Neurosci. 18, 547–558 (2017).

Article  CAS  PubMed  Google Scholar 

Yuste, R. From the neuron doctrine to neural networks. Nat. Rev. Neurosci. 16, 487–497 (2015).

Article  CAS  PubMed  Google Scholar 

Ohiorhenuan, I. E. et al. Sparse coding and high-order correlations in fine-scale cortical networks. Nature 466, 617–621 (2010).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Panzeri, S., Moroni, M., Safaai, H. & Harvey, C. D. The structures and functions of correlations in neural population codes. Nat. Rev. Neurosci. 23, 551–567 (2022).

Article  CAS  PubMed  Google Scholar 

Shahidi, N., Andrei, A. R., Hu, M. & Dragoi, V. High-order coordination of cortical spiking activity modulates perceptual accuracy. Nat. Neurosci. 22, 1148–1158 (2019).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Balaguer-Ballester, E., Nogueira, R., Abolafia, J. M., Moreno-Bote, R. & Sanchez-Vives, M. V. Representation of foreseeable choice outcomes in orbitofrontal cortex triplet-wise interactions. PLoS Comput. Biol. 16, e1007862 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vogels, T. P., Rajan, K. & Abbott, L. F. Neural network dynamics. Annu Rev. Neurosci. 28, 357–376 (2005).

Article  CAS  PubMed  Google Scholar 

Peters, A. J., Chen, S. X. & Komiyama, T. Emergence of reproducible spatiotemporal activity during motor learning. Nature 510, 263–267 (2014).

Article  CAS  PubMed  Google Scholar 

LaFerla, F. M., Green, K. N. & Oddo, S. Intracellular amyloid-β in Alzheimer’s disease. Nat. Rev. Neurosci. 8, 499–509 (2007).

Article  CAS  PubMed  Google Scholar 

Mucke, L. et al. High-level neuronal expression of aβ 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J. Neurosci. 20, 4050–4058 (2000).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Terry, R. D. et al. Physical basis of cognitive alterations in Alzheimer’s disease: synapse loss is the major correlate of cognitive impairment. Ann. Neurol. 30, 572–580 (1991).

Article  CAS  PubMed  Google Scholar 

Morris, G. P., Clark, I. A. & Vissel, B. Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer’s disease. Acta Neuropathol. Commun. 2, 135 (2014).

PubMed  PubMed Central  Google Scholar 

Hsieh, H. et al. AMPAR removal underlies Aβ-induced synaptic depression and dendritic spine loss. Neuron 52, 831–843 (2006).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Du, Y. et al. TRPV1 activation alleviates cognitive and synaptic plasticity impairments through inhibiting AMPAR endocytosis in APP23/PS45 mouse model of Alzheimer’s disease. Aging Cell 19, e13113 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chishti, M. A. et al. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J. Biol. Chem. 276, 21562–21570 (2001).

Article  CAS  PubMed  Google Scholar 

Yiu, A. P., Rashid, A. J. & Josselyn, S. A. Increasing CREB Function in the CA1 region of dorsal hippocampus rescues the spatial memory deficits in a mouse model of Alzheimer’s disease. Neuropsychopharmacology https://doi.org/10.1038/npp.2011.107 (2011).

Xia, F. et al. Entorhinal cortical deep-brain stimulation rescues memory deficits in both young and old mice genetically engineered to model Alzheimer’s disease. Neuropsychopharmacology https://doi.org/10.1038/npp.2017.100 (2017).

Morris, R. G., Garrud, P., Rawlins, J. N. & O’Keefe, J. Place navigation impaired in rats with hippocampal lesions. Nature 297, 681–683 (1982).

Article  CAS  PubMed  Google Scholar 

Cole, C. J. et al. MEF2 negatively regulates learning-induced structural plasticity and memory formation. Nat. Neurosci. 15, 1255–1264 (2012).

Article  CAS  PubMed  Google Scholar 

Moser, M. B., Trommald, M. & Andersen, P. An increase in dendritic spine density on hippocampal CA1 pyramidal cells following spatial learning in adult rats suggests the formation of new synapses. Proc. Natl Acad. Sci. USA 91, 12673–12675 (1994).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Epp, J. R. et al. Optimization of CLARITY for clearing whole-brain and other intact organs(1,2,3). eNeuro 2, ENEURO.0022-15.2015 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Chung, K. & Deisseroth, K. CLARITY for mapping the nervous system. Nat. Methods 10, 508–513 (2013).

Article  CAS  PubMed  Google Scholar 

Citron, M. et al. Excessive production of amyloid β-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation. PNAS 91, 11993–11997 (1994).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brebner, K. et al. Nucleus accumbens long-term depression and the expression of behavioral sensitization. Science 310, 1340–1343 (2005).

Article  CAS  PubMed  Google Scholar 

Oakley, H. et al. Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer’s disease mutations: potential factors in amyloid plaque formation. J. Neurosci. 26, 10129–10140 (2006).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maren, S., Aharonov, G. & Fanselow, M. S. Neurotoxic lesions of the dorsal hippocampus and Pavlovian fear conditioning in rats. Behav. Brain Res 88, 261–274 (1997).

Article  CAS  PubMed  Google Scholar 

He, K., Lee, A., Song, L., Kanold, P. O. & Lee, H. K. AMPA receptor subunit GluR1 (GluA1) serine-845 site is involved in synaptic depression but not in spine shrinkage associated with chemical long-term depression. J. Neurophysiol. 105, 1897–1907 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jacob, A. D. et al. A compact head-mounted endoscope for in vivo calcium imaging in freely behaving mice. Curr. Protoc. Neurosci. 84, e51 (2018).

Article  PubMed  Google Scholar 

Mocle, A. J. et al. Excitability mediates allocation of pre-configured ensembles to a hippocampal engram supporting contextual conditioned threat in mice. Neuron 112, 1487–1497.e1486 (2024).

Article  CAS  PubMed  Google Scholar 

de Snoo, M. L., Miller, A. M. P., Ramsaran, A. I., Josselyn, S. A. & Frankland, P. W. Exercise accelerates place cell representational drift. Curr. Biol. 33, R96–R97 (2023).

留言 (0)

沒有登入
gif