M.C received grant from Boston Scientific and Edwards Lifesciences; she has served as consultant for Jenscare Scientific. J.M. is a proctor for Boston Scientific. B. E. S. has been supported by a donation of H.H. Sheikh Khalifa bin Hamad Al-Thani to the University of Zurich, Switzerland, and research grants to the institution from the OPO Foundation, the Iten-Kohaut Foundation, the German Center for Cardiovascular Research (DZHK), the German Heart Research Foundation, the B. Braun Foundation, Boston Scientific, and Edwards Lifesciences. B. E. S. has received consulting and speaker fees from Boston Scientific, Abbott Vascular, and MedAlliance, she is a Steering Committee Member of the Cruz Senior Study (SMT). A.M.K is a consultant and proctor for Edwards Lifesciences and received grants to the institution from Edwards Lifesciences. The remaining authors have nothing to disclose.