Abd Elghani SA, Oda SS, Tohamy HG, Hashem MA (2020) Hematological, biochemical and histopathological studies on the prophylactic effect of zinc sulphate against mercuric chloride toxicity in rats. Alex J Vet Sci 64:102–109

Google Scholar 

Abu-Zeid EH, Khalifa BA, Elewa YHA, Arisha AH, Ismail TA, Hendam BM, Abdel-Hamid SE (2021) Bee venom Apis mellifera lamarckii rescues blood brain barrier damage and neurobehavioral changes induced by methyl mercury via regulating tight junction proteins expression in rat cerebellum. Food Chem Toxicol 154:112309

Article  CAS  PubMed  Google Scholar 

Ahmad S, Mahmood R (2019) Mercury chloride toxicity in human erythrocytes: enhanced generation of ROS and RNS, hemoglobin oxidation, impaired antioxidant power, and inhibition of plasma membrane redox system. Environ Sci Pollut Res Int 26:5645–5657

Article  CAS  PubMed  Google Scholar 

Aktas I, Gur FM (2022) Hepato-protective effects of thymoquinone and beta-aminoisobutyric acid in streptozocin induced diabetic rats. Biotech Histochem 97:67–76

Article  CAS  PubMed  Google Scholar 

Aktas I, Yahyazadeh A (2022) Protective potential of misoprostol against kidney alteration via alleviating oxidative stress in rat following exposure to paclitaxel. Tissue Cell 79:101966

Article  CAS  PubMed  Google Scholar 

Al-Taee H, Azimullah S, Meeran MFN, Alaraj Almheiri MK, Al Jasmi RA, Tariq S, Ab Khan M, Adeghate E, Ojha S (2019) Beta-caryophyllene, a dietary phytocannabinoid attenuates oxidative stress, inflammation, apoptosis and prevents structural alterations of the myocardium against doxorubicin-induced acute cardiotoxicity in rats: an in vitro and in vivo study. Eur J Pharmacol 858:172467

Article  CAS  PubMed  Google Scholar 

Altunkaynak BZ, Akgul N, Yahyazedeh A, Makaraci E, Akgul HM (2019) A stereological study of the effects of mercury inhalation on the cerebellum. Biotech Histochem 94:42–47

Article  CAS  PubMed  Google Scholar 

Ames-Sibin AP, Barizao CL, Castro-Ghizoni CV, Silva FMS, Sa-Nakanishi AB, Bracht L, Bersani-Amado CA, Marcal-Natali MR, Bracht A, Comar JF (2018) Beta-caryophyllene, the major constituent of copaiba oil, reduces systemic inflammation and oxidative stress in arthritic rats. J Cell Biochem 119:10262–10277

Article  CAS  PubMed  Google Scholar 

Angelova PR, Esteras N, Abramov AY (2021) Mitochondria and lipid peroxidation in the mechanism of neurodegeneration: finding ways for prevention. Med Res Rev 41:770–784

Article  CAS  PubMed  Google Scholar 

Balcioglu E, Gur FM, Gur HE, Bilgici P, Kankilic T (2021) Histological structure of Nannospalax xanthodon cochlea tissue. Biologia 76:2543–2548

Article  CAS  Google Scholar 

Baldissera MD, Souza CF, Grando TH, Doleski PH, Boligon AA, Stefani LM, Monteiro SG (2017) Hypolipidemic effect of beta-caryophyllene to treat hyperlipidemic rats. Naunyn Schmiedebergs Arch Pharmacol 390:215–223

Article  CAS  PubMed  Google Scholar 

Behzadfar L, Hassani S, Feizpour H, Abbasian N, Salek Maghsoudi A, Taghizadeh G, Pourahmad J, Sharifzadeh M (2020) Effects of mercuric chloride on spatial memory deficit-induced by beta-amyloid and evaluation of mitochondrial function markers in the hippocampus of rats. Metallomics 12:144–153

Article  CAS  PubMed  Google Scholar 

Bjorklund G, Skalny AV, Rahman MM, Dadar M, Yassa HA, Aaseth J, Chirumbolo S, Skalnaya MG, Tinkov AA (2018) Toxic metal(loid)-based pollutants and their possible role in autism spectrum disorder. Environ Res 166:234–250

Article  PubMed  Google Scholar 

Bridges CC, Zalups RK (2017) Mechanisms involved in the transport of mercuric ions in target tissues. Arch Toxicol 91:63–81

Article  CAS  PubMed  Google Scholar 

Cappelletti S, Piacentino D, Fineschi V, Frati P, D’Errico S, Aromatario M (2019) Mercuric chloride poisoning: symptoms, analysis, therapies, and autoptic findings. A review of the literature. Crit Rev Toxicol 49:329–341

Article  CAS  PubMed  Google Scholar 

Chen DJ, Gao M, Gao FF, Su QX, Wu J (2017) Brain cannabinoid receptor 2: expression, function and modulation. Acta Pharmacol Sin 38:312–316

Article  CAS  PubMed  PubMed Central  Google Scholar 

Clarkson TW, Magos L (2006) The toxicology of mercury and its chemical compounds. Crit Rev Toxicol 36:609–662

Article  CAS  PubMed  Google Scholar 

Cooper GP, Manalis RS (1983) Influence of heavy metals on synaptic transmission: a review. Neurotoxicology 4:69–83

CAS  PubMed  Google Scholar 

Correa MG, Bittencourt LO, Nascimento PC, Ferreira RO, Aragao WAB, Silva MCF, Gomes-Leal W, Fernandes MS, Dionizio A, Buzalaf MR, Crespo-Lopez ME, Lima RR (2020) Spinal cord neurodegeneration after inorganic mercury long-term exposure in adult rats: ultrastructural, proteomic and biochemical damages associated with reduced neuronal density. Ecotoxicol Environ Saf 191:110159

Article  CAS  PubMed  Google Scholar 

da Costa R, Passos GF, Quintao NLM, Fernandes ES, Maia J, Campos MM, Calixto JB (2020) Taxane-induced neurotoxicity: pathophysiology and therapeutic perspectives. Br J Pharmacol 177:3127–3146

Article  PubMed  PubMed Central  Google Scholar 

Denny MF, Atchison WD (1996) Mercurial-induced alterations in neuronal divalent cation homeostasis. Neurotoxicology 17:47–61

CAS  PubMed  Google Scholar 

Dizdaroglu M, Jaruga P (2012) Mechanisms of free radical-induced damage to DNA. Free Radic Res 46:382–419

Article  CAS  PubMed  Google Scholar 

Do SY, Lee CG, Kim JY, Moon YH, Kim MS, Bae IH, Song HS (2017) Cases of acute mercury poisoning by mercury vapor exposure during the demolition of a fluorescent lamp factory. Ann Occup Environ Med 29:19

Article  PubMed  PubMed Central  Google Scholar 

Endo T, Nakaya S, Kimura R (1990) Mechanisms of absorption of inorganic mercury from rat small intestine. III. Comparative absorption studies of inorganic mercuric compounds in vitro. Pharmacol Toxicol 66:347–353

Article  CAS  PubMed  Google Scholar 

Fernandes Azevedo B, Barros Furieri L, Pecanha FM, Wiggers GA, Frizera Vassallo P, Ronacher Simoes M, Fiorim J, Rossi de Batista P, Fioresi M, Rossoni L, Stefanon I, Alonso MJ, Salaices M, Valentim Vassallo D (2012) Toxic effects of mercury on the cardiovascular and central nervous systems. J Biomed Biotechnol 2012:949048

Article  PubMed  PubMed Central  Google Scholar 

Ferraro L, Tomasini MC, Tanganelli S, Mazza R, Coluccia A, Carratu MR, Gaetani S, Cuomo V, Antonelli T (2009) Developmental exposure to methylmercury elicits early cell death in the cerebral cortex and long-term memory deficits in the rat. Int J Dev Neurosci 27:165–174

Article  CAS  PubMed  Google Scholar 

Fujii J, Tsunoda S (2011) Redox regulation of fertilisation and the spermatogenic process. Asian J Androl 13:420–423

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gasso S, Cristofol RM, Selema G, Rosa R, Rodriguez-Farre E, Sanfeliu C (2001) Antioxidant compounds and Ca(2+) pathway blockers differentially protect against methylmercury and mercuric chloride neurotoxicity. J Neurosci Res 66:135–145

Article  CAS  PubMed  Google Scholar 

Gu L, Jin F, Yang T, Ruan Y, Zhong R, Han Q, Huang Y (2023) Mercuric chloride induced brain toxicity in mice: the protective effects of puerarin-loaded PLGA nanoparticles. J Biochem Mol Toxicol 37:e23425

Article  CAS  PubMed  Google Scholar 

Guo C, Sun L, Chen X, Zhang D (2013) Oxidative stress, mitochondrial damage and neurodegenerative diseases. Neural Regen Res 8:2003–2014

CAS  PubMed  PubMed Central  Google Scholar 

Gur FM (2022) Immunoexpression of androgen receptor in genital tissues of male BALB/c mice. Annals Med Res 29:1049–1053

Google Scholar