Abame MA, He Y, Wu S, Xie Z, Zhang J, Gong X, Wu C, Shen J (2021) Chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus. Neurosci Lett 744:135594. https://doi.org/10.1016/j.neulet.2020.135594

Article  CAS  PubMed  Google Scholar 

Antoniuk S, Bijata M, Ponimaskin E, Wlodarczyk J (2019) Chronic unpredictable mild stress for modeling depression in rodents: Meta-analysis of model reliability. Neurosci Biobehav Rev 99:101–116. https://doi.org/10.1016/j.neubiorev.2018.12.002

Article  PubMed  Google Scholar 

Arisi GM (2014) Nervous and immune systems signals and connections: cytokines in hippocampus physiology and pathology. Epilepsy Behav 38:43–47. https://doi.org/10.1016/j.yebeh.2014.01.017

Article  PubMed  Google Scholar 

Bhatt S, Nagappa AN, Patil CR (2020) Role of oxidative stress in depression. Drug Discov Today 25(7):1270–1276. https://doi.org/10.1016/j.drudis.2020.05.001

Article  CAS  PubMed  Google Scholar 

Boros M, Ghyczy M, Érces D, Varga G, Tőkés T, Kupai K, Torday C, Kaszaki J (2012) The anti-inflammatory effects of methane. Crit Care Med 40(4):1269–78. https://doi.org/10.1097/ccm.0b013e31823dae05

Article  CAS  PubMed  Google Scholar 

Borsini A, Giacobbe J, Mandal G, Boldrini M (2023) Acute and long-term effects of adolescence stress exposure on rodent adult hippocampal neurogenesis, cognition, and behaviour. Mol Psychiatry 28(10):4124–4137. https://doi.org/10.1038/s41380-023-02229-2

Article  PubMed  PubMed Central  Google Scholar 

Bosch K, Sbrini G, Burattini I, Nieuwenhuis D, Calabrese F, Schubert D, Henckens MJ, Homberg JR (2022) Repeated testing modulates chronic unpredictable mild stress effects in male rats. Behav Brain Res 432:113960. https://doi.org/10.1016/j.bbr.2022.113960

Article  PubMed  Google Scholar 

Chen O, Ye Z, Cao Z, Manaenko A, Ning K, Zhai X, Zhang R, Zhang T, Chen X, Liu W (2016) Methane attenuates myocardial ischemia injury in rats through anti-oxidative, anti-apoptotic and anti-inflammatory actions. Free Radic Biol Med 90:1–11. https://doi.org/10.1016/j.freeradbiomed.2015.11.017

Article  CAS  PubMed  Google Scholar 

Jain S, Banerjee BD, Ahmed RS, Arora VK, Mediratta PK (2013) Possible role of oxidative stress and brain derived neurotrophic factor in triazophos induced cognitive impairment in rats. Neurochem Res 38:2136–2147. https://doi.org/10.1007/s11064-013-1122-0

Article  CAS  PubMed  Google Scholar 

Jia Y, Li Z, Liu C, Zhang J (2018) Methane medicine: a rising star gas with powerful anti-inflammation, antioxidant, and antiapoptosis properties. Oxid Med Cell Longev 201:1912746. https://doi.org/10.1155/2018/1912746

Article  CAS  Google Scholar 

Johnson SA, Fournier NM, Kalynchuk LE (2006) Effect of different doses of corticosterone on depression-like behavior and HPA axis responses to a novel stressor. Behav Brain Res 168(2):280–288. https://doi.org/10.1016/j.bbr.2005.11.019

Article  CAS  PubMed  Google Scholar 

Juszczyk G, Mikulska J, Kasperek K, Pietrzak D, Mrozek W, Herbet M (2021) Chronic stress and oxidative stress as common factors of the pathogenesis of depression and Alzheimer’s disease: the role of antioxidants in prevention and treatment. Antioxidants 10(9):1439. https://doi.org/10.3390/antiox10091439

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kalia M (2005) Neurobiological basis of depression: an update. Metab 54(5):24–27. https://doi.org/10.1016/j.metabol.2005.01.009

Article  CAS  Google Scholar 

Kim EJ, Pellman B, Kim JJ (2015) Stress effects on the hippocampus: a critical review. Learn Mem 22(9):411–416. https://doi.org/10.1101/lm.037291.114

Article  PubMed  PubMed Central  Google Scholar 

Li M, Gao W, Ji L, Li J, Jiang W, Ji W (2020) Methane saline ameliorates traumatic brain injury through anti-inflammatory, antiapoptotic, and antioxidative effects by activating the Wnt signalling pathway. Biomed Res Int 2020:3852450. https://doi.org/10.1155/2020/3852450

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li Z, Ruan M, Chen J, Fang Y (2021) Major depressive disorder: advances in neuroscience research and translational applications. Neurosci Bull 37(6):863–880. https://doi.org/10.1007/s12264-021-00638-3

Article  PubMed  PubMed Central  Google Scholar 

Li H, Song L, Cen M, Fu X, Gao X, Zuo Q, Wu J (2023) Oxidative balance scores and depressive symptoms: mediating effects of oxidative stress and inflammatory factors. J J Affect Disord 334:205–212. https://doi.org/10.1016/j.jad.2023.04.134

Article  CAS  PubMed  Google Scholar 

Liu L, Sun Q, Wang R, Chen Z, Wu J, Xia F, Xq Fan (2016) Methane attenuates retinal ischemia/reperfusion injury via anti-oxidative and anti-apoptotic pathways. Brain Res 1646:327–333. https://doi.org/10.1016/j.brainres.2016.05.037

Article  CAS  PubMed  Google Scholar 

Mészáros AT, Szilágyi ÁL, Juhász L, Tuboly E, Érces D, Varga G, Hartmann P (2017) Mitochondria as sources and targets of methane. Front Med (Lausanne) 4:195. https://doi.org/10.3389/fmed.2017.00195

Article  PubMed  Google Scholar 

Mifsud KR, Reul JM (2016) Acute stress enhances heterodimerization and binding of corticosteroid receptors at glucocorticoid target genes in the hippocampus. PNAS 113(40):11336–11341. https://doi.org/10.1073/pnas.1605246113

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mileva GR, Rooke J, Ismail N, Bielajew C (2017) Corticosterone and immune cytokine characterization following environmental manipulation in female WKY rats. Behav Brain Res 316:197–204. https://doi.org/10.1016/j.bbr.2016.09.004

Article  CAS  PubMed  Google Scholar 

Niknazar S, Nahavandi A, Peyvandi AA, Peyvandi H, Zare Mehrjerdi F, Karimi M (2017) Effect of maternal stress prior to conception on hippocampal BDNF signaling in rat offspring. Mol Neurobiol 54:6436–6445. https://doi.org/10.1007/s12035-016-0143-5

Article  CAS  PubMed  Google Scholar 

Palta P, Samuel LJ, MillerIII ER, Szanton SL (2014) Depression and oxidative stress: results from a meta-analysis of observational studies. Psychosom Med 76(1):12. https://doi.org/10.1097/psy.0000000000000009

Article  CAS  PubMed  Google Scholar 

Poles MZ, Juhász L, Boros M (2019) Methane and inflammation - a review (fight fire with fire). Intensive Care Med Exp 7(1):68. https://doi.org/10.1186/s40635-019-0278-6

Article  PubMed  PubMed Central  Google Scholar 

Salari M, Zare Mehrjerdi F, Yadegari M, Rezvani ME, Shahrokhi Raeini A (2023) Antidepressant-like effect of endogenous SO2 on depression caused by chronic unpredictable mild stress. Naunyn Schmiedebergs Arch Pharmacol 396(6):1325–1336. https://doi.org/10.1007/s00210-023-02405-9

Article  CAS  PubMed  Google Scholar 

Saveanu RV, Nemeroff CB (2012) Etiology of depression: genetic and environmental factors. Psychiatric Clin 35(1):51–71. https://doi.org/10.1016/j.psc.2011.12.001

Article  Google Scholar 

Shahidpour M, Zare FM, Mozayan MR, Marefati N, Hosseini H (2021) The effects of frankincense extract on depression and anxiety-like behaviors induced by lipopolysaccharide in rats. Learn Motiv 73:101708. https://doi.org/10.1016/j.lmot.2021.101708

Article  Google Scholar 

Shen M, Fan D, Zang Y, Chen Y, Zhu K, Cai Z, Liu Y, Sun X, Liu J, Gong J (2016) Neuroprotective effects of methane-rich saline on experimental acute carbon monoxide toxicity. J Neurol Sci 369:361–367. https://doi.org/10.1016/j.jns.2016.08.055

Article  CAS  PubMed