Atkinson MA, Eisenbarth GS, Michels AW (2014) Type 1 diabetes. Lancet 383(9911):69–82

Article  PubMed  Google Scholar 

Maahs DM, West NA, Lawrence JM, Mayer-Davis EJ (2010) Epidemiology of type 1 diabetes. Endocrinol Metab Clin North Am 39(3):481–497

Article  PubMed  PubMed Central  Google Scholar 

Passanisi S, Salzano G, Bombaci B, Lombardo F (2021) Clinical and genetic features of maturity-onset diabetes of the young in pediatric patients: a 12-year monocentric experience. Diabetol Metab Syndr 13(1):96

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gregory GA, Robinson TIG, Linklater SE, Wang F, Colagiuri S, de Beaufort C et al (2022) Global incidence, prevalence, and mortality of type 1 diabetes in 2021 with projection to 2040: a modelling study. Lancet Diabetes Endocrinol 10(10):741–760

Article  PubMed  Google Scholar 

Prentice A, Schoenmakers I, Laskey MA, de Bono S, Ginty F, Goldberg GR (2006) Nutrition and bone growth and development. Proc Nutr Soc 65(4):348–360

Article  CAS  PubMed  PubMed Central  Google Scholar 

Weaver CM, Gordon CM, Janz KF, Kalkwarf HJ, Lappe JM, Lewis R et al (2016) The National Osteoporosis Foundation’s position statement on peak bone mass development and lifestyle factors: a systematic review and implementation recommendations. Osteoporos Int 27(4):1281–1386

Article  CAS  PubMed  PubMed Central  Google Scholar 

Madsen JOB, Jørgensen NR, Pociot F, Johannesen J (2019) Bone turnover markers in children and adolescents with type 1 diabetes—A systematic review. Pediatr Diabetes 20(5):510–522

CAS  PubMed  Google Scholar 

Karsenty G (2023) Osteocalcin: A Multifaceted Bone-Derived Hormone. Annu Rev Nutr 43:55–71

Article  CAS  PubMed  PubMed Central  Google Scholar 

Komori T (2020) Functions of osteocalcin in bone, pancreas, testis, and muscle. Int J Mol Sci 21(20):7513

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kuo TR, Chen CH (2017) Bone biomarker for the clinical assessment of osteoporosis: recent developments and future perspectives. Biomark Res 5:18

Article  PubMed  PubMed Central  Google Scholar 

Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C et al (2007) Endocrine regulation of energy metabolism by the skeleton. Cell 130(3):456–469

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sabek OM, Nishimoto SK, Fraga D, Tejpal N, Ricordi C, Gaber AO (2015) Osteocalcin effect on human β-Cells mass and function. Endocrinology 156(9):3137–3146

Article  CAS  PubMed  Google Scholar 

Madsen JOB, Herskin CW, Zerahn B, Jørgensen NR, Olsen BS, Pociot F et al (2020) reased markers of bone turnover in children and adolescents with type 1 diabetes. Pediatr Diabetes 21(3):505–514

Article  CAS  PubMed  Google Scholar 

ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D et al (2023) Classification and Diagnosis of Diabetes: Standards of Care in Diabetes-2023. Diabetes Care. https://doi.org/10.2337/dc23-S002

Article  PubMed  PubMed Central  Google Scholar 

Glaser N, Fritsch M, Priyambada L, Rewers A, Cherubini V, Estrada S et al (2022) ISPAD clinical practice consensus guidelines 2022: Diabetic ketoacidosis and hyperglycemic hyperosmolar state. Pediatr Diabetes 23(7):835–856

Article  PubMed  Google Scholar 

Zhao C, Liang J, Yang Y, Yu M, Qu X (2017) The Impact of Glucagon-Like Peptide-1 on Bone Metabolism and Its Possible Mechanisms. Front Endocrinol 8:98

Article  Google Scholar 

Otani T, Mizokami A, Hayashi Y, Gao J, Mori Y, Nakamura S et al (2015) Signaling pathway for adiponectin expression in adipocytes by osteocalcin. Cell Signal 27(3):532–544

Article  CAS  PubMed  Google Scholar 

Ferron M, Lacombe J (2014) Regulation of energy metabolism by the skeleton: osteocalcin and beyond. Arch Biochem Biophys 561:137–146

Article  CAS  PubMed  Google Scholar 

Obri A, Khrimian L, Karsenty G, Oury F (2018) Osteocalcin in the brain: from embryonic development to age-related decline in cognition. Nat Rev Endocrinol 14(3):174–182

Article  CAS  PubMed  PubMed Central  Google Scholar 

Du J, Zhang M, Lu J, Zhang X, Xiong Q, Xu Y et al (2016) Osteocalcin improves nonalcoholic fatty liver disease in mice through activation of Nrf2 and inhibition of JNK. Endocrine 53(3):701–709

Article  CAS  PubMed  Google Scholar 

Pi M, Faber P, Ekema G, Jackson PD, Ting A, Wang N et al (2005) Identification of a novel extracellular cation-sensing G-protein-coupled receptor. J Biol Chem 280(48):40201–40209

Article  CAS  PubMed  Google Scholar 

Pi M, Kapoor K, Ye R, Nishimoto SK, Smith JC, Baudry J et al (2016) Evidence for osteocalcin binding and activation of GPRC6A in β-Cells. Endocrinology 157(5):1866–1880

Article  CAS  PubMed  PubMed Central  Google Scholar 

Karalazou P, Ntelios D, Chatzopoulou F, Fragou A, Taousani M, Mouzaki K et al (2019) OPG/RANK/RANKL signaling axis in patients with type I diabetes: Associations with parathormone and vitamin D. Ital J Pediatr 45(1):161

Article  CAS  PubMed  PubMed Central  Google Scholar 

Palui R, Pramanik S, Mondal S, Ray S (2021) Critical review of bone health, fracture risk and management of bone fragility in diabetes mellitus. World J Diabetes 12(6):706–729

Article  PubMed  PubMed Central  Google Scholar 

Yoshida K, Urakami T, Morioka I (2021) Glucagon stimulation test as a possible predictor of residual β-cell function. Pediatr Int 63(5):536–542

Article  CAS  PubMed  Google Scholar 

Sabek OM, Redondo MJ, Nguyen DT, Beamish CA, Fraga DW, Hampe CS et al (2020) Serum C-peptide and osteocalcin levels in children with recently diagnosed diabetes. Endocrinol Diabetes Metab 3(1):e00104

Article  PubMed  Google Scholar 

Redondo MJ, Shirkey BA, Fraga DW, Gaber AO, Sabek OM (2017) Serum undercarboxylated osteocalcin correlates with hemoglobin A1c in children with recently diagnosed pediatric diabetes. Pediatr Diabetes 18(8):869–873

Article  CAS  PubMed  Google Scholar 

Jamiołkowska-Sztabkowska M, Głowińska-Olszewska B, Bossowski A (2021) C-peptide and residual β-cell function in pediatric diabetes - state of the art. Pediatr Endocrinol Diabetes Metab 27(2):123–133

Article  PubMed  PubMed Central  Google Scholar 

Massry SG, Kurokawa K, Arieff AI, Ben-Isaac C (1974) Editorial: Metabolic acidosis of hyperparathyroidism. Arch Intern Med 134(2):385–387

Article  CAS  PubMed  Google Scholar 

Oh SB, Lee WY, Nam HK, Rhie YJ, Lee KH (2019) Serum osteocalcin levels in overweight children. Ann Pediatr Endocrinol Metab 24(2):104–107

Article  PubMed  PubMed Central  Google Scholar