Jakhotia S, Kavvuri R, Raviraj S, Baishya S, Pasupulati AK, Reddy GB. Obesity-related glomerulopathy is associated with elevated WT1 expression in podocytes. Int J Obes (Lond). 2024 https://doi.org/10.1038/s41366-024-01509-3.

Nelson RG, Grams ME, Ballew SH, Sang Y, Azizi F, Chadban SJ, et al. CKD Prognosis Consortium. Development of risk prediction equations for incident chronic kidney disease. JAMA. 2019;322:2104–14.

Article  PubMed  PubMed Central  Google Scholar 

Kambham N, Markowitz GS, Valeri AM, Lin J, D’Agati VD. Obesity-related glomerulopathy: an emerging epidemic. Kidney Int. 2001;59:1498–509.

Article  CAS  PubMed  Google Scholar 

D’Agati VD, Chagnac A, de Vries AP, Levi M, Porrini E, Herman-Edelstein M, et al. Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis. Nat Rev Nephrol. 2016;12:453–71.

Article  PubMed  Google Scholar 

Praga M, Hernández E, Herrero JC, Morales E, Revilla Y, Díaz-González R, et al. Influence of obesity on the appearance of proteinuria and renal insufficiency after unilateral nephrectomy. Kidney Int. 2000;58:2111–8.

Article  CAS  PubMed  Google Scholar 

Tsuboi N, Koike K, Hirano K, Utsunomiya Y, Kawamura T, Hosoya T. Clinical features and long-term renal outcomes of Japanese patients with obesity-related glomerulopathy. Clin Exp Nephrol. 2013;17:379–85.

Article  PubMed  Google Scholar 

Okabayashi Y, Tsuboi N, Sasaki T, Haruhara K, Kanzaki G, Koike K, et al. Single-nephron GFR in patients with obesity-related glomerulopathy. Kidney Int Rep. 2020;5:1218–27.

Article  PubMed  PubMed Central  Google Scholar 

Fukuda A, Chowdhury MA, Venkatareddy MP, Wang SQ, Nishizono R, Suzuki T, et al. Growth-dependent podocyte failure causes glomerulosclerosis. J Am Soc Nephrol. 2012;23:1351–63.

Article  CAS  PubMed  PubMed Central  Google Scholar 

The EMPA-KIDNEY Collaborative Group, Herrington WG, Staplin N, Wanner C, Green JB, Hauske SJ, et al. Empagliflozin in patients with chronic kidney disease. N Engl J Med. 2023;388:117–27.

Article  Google Scholar 

Ettou S, Jung YL, Miyoshi T, Jain D, Hiratsuka K, Schumacher V, et al. Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury. Sci Adv. 2020;6:eabb5460.

Article  CAS  PubMed  PubMed Central  Google Scholar