Pure Apocrine Intraductal Carcinoma of Salivary Glands: Reassessment of Molecular Underpinnings and Behavior

Brandwein-Gensler M, Gnepp DR (2005) Low-grade cribriform cystadenocarcinoma. In: Barnes L, Eveson JW, Reichart P, Sidransky D (eds) Pathology and genetics of head and neck tumours. World Health Organization classification of tumours, Lyon

Google Scholar 

Brandwein-Gensler M, Hille J, Wang BY, Urken M, Gordon R, Wang LJ et al (2004) Low-grade salivary duct carcinoma: description of 16 cases. Am J Surg Pathol 28(8):1040–1044

Article  PubMed  Google Scholar 

Chen KT (1983) Intraductal carcinoma of the minor salivary gland. J Laryngol Otol 97(2):189–191

Article  CAS  PubMed  Google Scholar 

Delgado R, Klimstra D, Albores-Saavedra J (1996) Low grade salivary duct carcinoma. A distinctive variant with a low grade histology and a predominant intraductal growth pattern. Cancer 78(5):958–967

Article  CAS  PubMed  Google Scholar 

Loening T, Leivo I, Simpson RHW, Weinreb I (2017) Intraductal carcinoma. In: El-Naggar A, Chan JK, Grandis JR, Takata T, Slootweg PJ (eds) WHO Classification of Head and Neck Tumours. International Agency for Research on Cancer, Lyon, pp 170–171

Google Scholar 

Skalova A, Ptakova N, Santana T, Agaimy A, Ihrler S, Uro-Coste E et al (2019) NCOA4-RET and TRIM27-RET are characteristic gene fusions in salivary intraductal carcinoma, including Invasive and Metastatic tumors: Is ‘“Intraductal”’ correct? Am J Surg Pathol 43(10):1303–1313

Article  PubMed  Google Scholar 

Skalova A, Vanecek T, Uro-Coste E, Bishop JA, Weinreb I, Thompson LDR et al (2018) Molecular profiling of salivary gland intraductal carcinoma revealed a subset of tumors harboring NCOA4-RET and novel TRIM27-RET fusions: a report of 17 cases. Am J Surg Pathol 42(11):1445–1455

Article  PubMed  Google Scholar 

Weinreb I, Bishop JA, Chiosea SI, Seethala RR, Perez-Ordonez B, Zhang L et al (2018) Recurrent RET gene rearrangements in intraductal carcinomas of salivary gland. Am J Surg Pathol 42(4):442–452

Article  PubMed  PubMed Central  Google Scholar 

Weinreb I, Tabanda-Lichauco R, Van der Kwast T, Perez-Ordonez B (2006) Low-grade intraductal carcinoma of salivary gland: report of 3 cases with marked apocrine differentiation. Am J Surg Pathol 30(8):1014–1021

Article  PubMed  Google Scholar 

Bishop JA, Nakaguro M, Whaley RD, Ogura K, Imai H, Laklouk I et al (2021) Oncocytic intraductal carcinoma of salivary glands: a distinct variant with TRIM33-RET fusions and BRAF V600E mutations. Histopathology 79(3):338–346

Article  PubMed  PubMed Central  Google Scholar 

Bishop JA, Gagan J, Krane JF, Jo VY (2020) Low-grade apocrine intraductal carcinoma: expanding the morphologic and molecular spectrum of an enigmatic salivary gland tumor. Head Neck Pathol. https://doi.org/10.1007/s12105-020-01128-0

Article  PubMed  PubMed Central  Google Scholar 

Bishop JA, Rooper LM, Sangoi AR, Gagan J, Thompson LDR, Inagaki H (2021) The myoepithelial cells of salivary intercalated duct-type intraductal carcinoma are neoplastic: a study using combined whole-slide imaging, immunofluorescence, and RET fluorescence in situ hybridization. Am J Surg Pathol 45(4):507–515

Article  PubMed  Google Scholar 

Hsieh MS, Lee YH, Jin YT, Kuo YJ (2020) Clinicopathological study of intraductal carcinoma of the salivary gland, with emphasis on the apocrine type. Virchows Arch. https://doi.org/10.1007/s00428-020-02823-7

Article  PubMed  Google Scholar 

Rooper LM, Thompson LDR, Gagan J, Oliai BR, Weinreb I, Bishop JA (2021) Salivary intraductal carcinoma arising within intraparotid lymph node: a report of 4 cases with identification of a novel STRN-ALK fusion. Head Neck Pathol 15(1):179–185

Article  PubMed  Google Scholar 

McLean-Holden AC, Rooper LM, Lubin DJ, Magliocca KR, Manucha V, Sadow PM et al (2022) Frankly invasive carcinoma ex-intraductal carcinoma: expanding on an emerging and perplexing concept in salivary gland tumor pathology. Head Neck Pathol. https://doi.org/10.1007/s12105-021-01408-3

Article  PubMed  PubMed Central  Google Scholar 

Thompson LDR, Bishop JA (2023) Salivary gland intraductal carcinoma: how do 183 reported cases fit into a developing classification. Adv Anat Pathol 30(2):112–129

Article  CAS  PubMed  Google Scholar 

Wenig BM, Hitchcock CL, Ellis GL, Gnepp DR (1992) Metastasizing mixed tumor of salivary glands. A clinicopathologic and flow cytometric analysis. Am J Surg Pathol 16(9):845–858

Article  CAS  PubMed  Google Scholar 

Seethala RR, Hunt JL, Baloch ZW, Livolsi VA, Leon BE (2007) Adenoid cystic carcinoma with high-grade transformation: a report of 11 cases and a review of the literature. Am J Surg Pathol 31(11):1683–1694

Article  PubMed  Google Scholar 

Wang K, Russell JS, McDermott JD, Elvin JA, Khaira D, Johnson A et al (2016) Profiling of 149 salivary duct carcinomas, carcinoma Ex pleomorphic adenomas, and adenocarcinomas, not otherwise specified reveals actionable genomic alterations. Clin Cancer Res 22(24):6061–6068

Article  CAS  PubMed  Google Scholar 

Dalin MG, Desrichard A, Katabi N, Makarov V, Walsh LA, Lee KW et al (2016) Comprehensive molecular characterization of salivary duct carcinoma reveals actionable targets and similarity to apocrine breast cancer. Clin Cancer Res 22(18):4623–4633

Article  CAS  PubMed  PubMed Central  Google Scholar 

Agaimy A, Baneckova M, Ihrler S, Mueller SK, Franchi A, Hartmann A et al (2021) ALK Rearrangements characterize 2 distinct types of salivary gland carcinomas: clinicopathologic and molecular analysis of 4 cases and literature review. Am J Surg Pathol 45(9):1166–1178

Article  PubMed  Google Scholar 

Dogan S, Ng CKY, Xu B, Kumar R, Wang L, Edelweiss M et al (2019) The repertoire of genetic alterations in salivary duct carcinoma including a novel HNRNPH3-ALK rearrangement. Hum Pathol 88:66–77

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kim Y, Song S, Lee M, Swatloski T, Kang JH, Ko YH et al (2020) Integrative genomic analysis of salivary duct carcinoma. Sci Rep 10(1):14995

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chiosea SI, Williams L, Griffith CC, Thompson LD, Weinreb I, Bauman JE et al (2015) Molecular characterization of apocrine salivary duct carcinoma. Am J Surg Pathol 39(6):744–752

Article  PubMed  Google Scholar 

Avirneni-Vadlamudi U, Galindo KA, Endicott TR, Paulson V, Cameron S, Galindo RL (2012) Drosophila and mammalian models uncover a role for the myoblast fusion gene TANC1 in rhabdomyosarcoma. J Clin Investig 122(1):403–407

Article  CAS  PubMed  Google Scholar 

Zhao X, Parpart S, Takai A, Roessler S, Budhu A, Yu Z et al (2015) Integrative genomics identifies YY1AP1 as an oncogenic driver in EpCAM(+) AFP(+) hepatocellular carcinoma. Oncogene 34(39):5095–5104

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yoshihara K, Wang Q, Torres-Garcia W, Zheng S, Vegesna R, Kim H et al (2015) The landscape and therapeutic relevance of cancer-associated transcript fusions. Oncogene 34(37):4845–4854

Article  CAS  PubMed  Google Scholar 

Mahdi H, Joehlin-Price A, Elishaev E, Dowlati A, Abbas A (2021) Genomic analyses of high-grade neuroendocrine gynecological malignancies reveal a unique mutational landscape and therapeutic vulnerabilities. Mol Oncol 15(12):3545–3558

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ho AL, Brana I, Haddad R, Bauman J, Bible K, Oosting S et al (2021) Tipifarnib in head and neck squamous cell carcinoma with HRAS mutations. J Clin Oncol 39(17):1856–1864

Article  CAS  PubMed  PubMed Central  Google Scholar 

留言 (0)

沒有登入
gif