This article explores the redesign of a Physician Associate (PA) programs didactic coursework from traditional lecture-based methods to a student-centered blended learning platform incorporating Team-Based Learning (TBL). The initiative, supported by a course innovation grant, aimed to address the limitations of passive learning by integrating active learning experiences that enhance student engagement and comprehension. The redesigned Diagnostic Methods I course leverages blended learning to combine online materials with face-to-face interactions, fostering critical thinking and practical application of knowledge. TBL, a structured approach to collaborative learning, facilitates deeper understanding through readiness assurance tests and team-based problem-solving. Early findings indicate improved student outcomes and positive perceptions of the blended TBL approach, suggesting its potential as a valuable educational strategy in PA programs. The article provides practical insights and lessons learned for educators seeking to implement TBL and blended learning in similar educational settings.

The authors have declared no competing interest.

This study did not receive any funding.

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Yes

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

Yes

I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.

Yes

All data produced in the present work are contained in the manuscript.