Prediction of O(6)-methylguanine-DNA methyltransferase promoter methylation status in IDH-wildtype glioblastoma using MRI histogram analysis

Chen X, Zhang M, Gan H, Wang H, Lee JH, Fang D, Kitange GJ, He L, Hu Z, Parney IF, Meyer FB, Giannini C, Sarkaria JN, Zhang Z (2018) A novel enhancer regulates MGMT expression and promotes temozolomide resistance in glioblastoma. Nat Commun 9(1):2949. https://doi.org/10.1038/s41467-018-05373-4

Article  CAS  PubMed  PubMed Central  Google Scholar 

Choi YS, Ahn SS, Kim DW, Chang JH, Kang SG, Kim EH, Kim SH, Rim TH, Lee SK (2016) Incremental prognostic value of ADC Histogram Analysis over MGMT promoter methylation status in patients with Glioblastoma. Radiology 281(1):175–184. https://doi.org/10.1148/radiol.2016151913

Article  PubMed  Google Scholar 

Drabycz S, Roldan G, de Robles P, Adler D, McIntyre JB, Magliocco AM, Cairncross JG, Mitchell JR (2010) An analysis of image texture, tumor location, and MGMT promoter methylation in glioblastoma using magnetic resonance imaging. NeuroImage 49(2):1398–1405. https://doi.org/10.1016/j.neuroimage.2009.09.049

Article  CAS  PubMed  Google Scholar 

Ellingson BM, Cloughesy TF, Pope WB, Zaw TM, Phillips H, Lalezari S, Nghiemphu PL, Ibrahim H, Naeini KM, Harris RJ, Lai A (2012) Anatomic localization of O6-methylguanine DNA methyltransferase (MGMT) promoter methylated and unmethylated tumors: a radiographic study in 358 de novo human glioblastomas. NeuroImage 59(2):908–916. https://doi.org/10.1016/j.neuroimage.2011.09.076

Article  CAS  PubMed  Google Scholar 

Gatto L, Franceschi E, Tosoni A, Di Nunno V, Tonon C, Lodi R, Agati R, Bartolini S, Brandes AA (2022) Beyond Imaging and Genetic Signature in Glioblastoma: radiogenomic holistic Approach in Neuro-Oncology. Biomedicines 10(12). https://doi.org/10.3390/biomedicines10123205

Gihr GA, Horvath-Rizea D, Kohlhof-Meinecke P, Ganslandt O, Henkes H, Richter C, Hoffmann KT, Surov A, Schob S (2018) Histogram Profiling of Postcontrast T1-Weighted MRI gives Valuable insights into Tumor Biology and enables prediction of growth kinetics and prognosis in Meningiomas. Transl Oncol 11(4):957–961. https://doi.org/10.1016/j.tranon.2018.05.009

Article  PubMed  PubMed Central  Google Scholar 

Han Y, Yan LF, Wang XB, Sun YZ, Zhang X, Liu ZC, Nan HY, Hu YC, Yang Y, Zhang J, Yu Y, Sun Q, Tian Q, Hu B, Xiao G, Wang W, Cui GB (2018) Structural and advanced imaging in predicting MGMT promoter methylation of primary glioblastoma: a region of interest based analysis. BMC Cancer 18(1):215. https://doi.org/10.1186/s12885-018-4114-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

He W, Li X, Hua J, Liao S, Guo L, Xiao X, Liu X, Zhou J, Wang W, Xu Y, Wu Y (2021) Noninvasive Assessment of O(6)-Methylguanine-DNA methyltransferase promoter methylation status in World Health Organization Grade II-IV Glioma using Histogram Analysis of Inflow-based vascular-space-occupancy combined with structural magnetic resonance imaging. J Magn Reson Imaging 54(1):227–236. https://doi.org/10.1002/jmri.27514

Article  PubMed  Google Scholar 

Hegi ME, Diserens AC, Gorlia T, Hamou MF, de Tribolet N, Weller M, Kros JM, Hainfellner JA, Mason W, Mariani L, Bromberg JE, Hau P, Mirimanoff RO, Cairncross JG, Janzer RC, Stupp R (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352(10):997–1003. https://doi.org/10.1056/NEJMoa043331

Article  CAS  PubMed  Google Scholar 

Lapointe S, Perry A, Butowski NA (2018) Primary brain tumours in adults. Lancet 392(10145):432–446. https://doi.org/10.1016/S0140-6736(18)30990-5

Article  PubMed  Google Scholar 

Liu X, Han T, Wang Y, Liu H, Huang X, Zhou J (2023) Differentiating angiomatous meningioma from atypical meningioma using histogram analysis of apparent diffusion coefficient maps. Quant Imaging Med Surg 13(7):4160–4170. https://doi.org/10.21037/qims-22-1224

Article  PubMed  PubMed Central  Google Scholar 

Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, Hawkins C, Ng HK, Pfister SM, Reifenberger G, Soffietti R, von Deimling A, Ellison DW (2021) The 2021 WHO classification of tumors of the Central Nervous System: a summary. Neuro Oncol 23(8):1231–1251. https://doi.org/10.1093/neuonc/noab106

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lu J, Li X, Li H (2021) Perfusion parameters derived from MRI for preoperative prediction of IDH mutation and MGMT promoter methylation status in glioblastomas. Magn Reson Imaging 83:189–195. https://doi.org/10.1016/j.mri.2021.09.005

Article  CAS  PubMed  Google Scholar 

Ostrom QT, Gittleman H, Fulop J, Liu M, Blanda R, Kromer C, Wolinsky Y, Kruchko C, Barnholtz-Sloan JS (2015) CBTRUS Statistical Report: primary brain and central nervous system tumors diagnosed in the United States in 2008–2012. Neuro Oncol 17(Suppl 4):iv1–iv62. https://doi.org/10.1093/neuonc/nov189

Article  PubMed  PubMed Central  Google Scholar 

Paz MF, Yaya-Tur R, Rojas-Marcos I, Reynes G, Pollan M, Aguirre-Cruz L, Garcia-Lopez JL, Piquer J, Safont MJ, Balana C, Sanchez-Cespedes M, Garcia-Villanueva M, Arribas L, Esteller M (2004) CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas. Clin Cancer Res 10(15):4933–4938. https://doi.org/10.1158/1078-0432.CCR-04-0392

Article  CAS  PubMed  Google Scholar 

Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, Janzer RC, Ludwin SK, Allgeier A, Fisher B, Belanger K, Hau P, Brandes AA, Gijtenbeek J, Marosi C, Vecht CJ, Mokhtari K, Wesseling P, Villa S, Eisenhauer E, Gorlia T, Weller M, Lacombe D, Cairncross JG, Mirimanoff RO, European Organisation for R, Treatment of Cancer Brain, Radiation Oncology T, G, National Cancer Institute of Canada Clinical Trials G (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10 (5):459–466. https://doi.org/10.1016/S1470-2045(09)70025-7

Wang G, Zhou J (2023) The value of whole-volume apparent diffusion coefficient histogram analysis in preoperatively distinguishing intracranial solitary fibrous tumor and transitional meningioma. Front Oncol 13:1155162. https://doi.org/10.3389/fonc.2023.1155162

Article  PubMed  PubMed Central  Google Scholar 

Weller M, Tabatabai G, Kastner B, Felsberg J, Steinbach JP, Wick A, Schnell O, Hau P, Herrlinger U, Sabel MC, Wirsching HG, Ketter R, Bahr O, Platten M, Tonn JC, Schlegel U, Marosi C, Goldbrunner R, Stupp R, Homicsko K, Pichler J, Nikkhah G, Meixensberger J, Vajkoczy P, Kollias S, Husing J, Reifenberger G, Wick W, Group DS (2015) MGMT promoter methylation is a strong prognostic biomarker for benefit from dose-intensified Temozolomide Rechallenge in Progressive Glioblastoma: the DIRECTOR trial. Clin Cancer Res 21(9):2057–2064. https://doi.org/10.1158/1078-0432.CCR-14-2737

Article  CAS  PubMed  Google Scholar 

Weller M, van den Bent M, Preusser M, Le Rhun E, Tonn JC, Minniti G, Bendszus M, Balana C, Chinot O, Dirven L, French P, Hegi ME, Jakola AS, Platten M, Roth P, Ruda R, Short S, Smits M, Taphoorn MJB, von Deimling A, Westphal M, Soffietti R, Reifenberger G, Wick W (2021) EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood. Nat Rev Clin Oncol 18(3):170–186. https://doi.org/10.1038/s41571-020-00447-z

Article  PubMed  Google Scholar 

Xi YB, Guo F, Xu ZL, Li C, Wei W, Tian P, Liu TT, Liu L, Chen G, Ye J, Cheng G, Cui LB, Zhang HJ, Qin W, Yin H (2018) Radiomics signature: a potential biomarker for the prediction of MGMT promoter methylation in glioblastoma. J Magn Reson Imaging 47(5):1380–1387. https://doi.org/10.1002/jmri.25860

Article  PubMed  Google Scholar 

Xue C, Zhou Q, Zhang P, Zhang B, Sun Q, Li S, Deng J, Liu X, Zhou J (2023) MRI histogram analysis of tumor-infiltrating CD8 + T cell levels in patients with glioblastoma. Neuroimage Clin 37:103353. https://doi.org/10.1016/j.nicl.2023.103353

Article  PubMed  PubMed Central  Google Scholar 

You SH, Choi SH, Kim TM, Park CK, Park SH, Won JK, Kim IH, Lee ST, Choi HJ, Yoo RE, Kang KM, Yun TJ, Kim JH, Sohn CH (2018) Differentiation of high-Grade from Low-Grade Astrocytoma: improvement in diagnostic accuracy and reliability of pharmacokinetic parameters from DCE MR Imaging by using arterial input functions obtained from DSC MR Imaging. Radiology 286(3):981–991. https://doi.org/10.1148/radiol.2017170764

Article  PubMed  Google Scholar 

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