Zwaan, C. M. et al. Collaborative efforts driving progress in pediatric acute myeloid leukemia. J. Clin. Oncol. 33, 2949–2962 (2015).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rasche, M. et al. Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012. Leukemia 32, 2167–2177 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Maloney, K. W. et al. Outcome in children with standard-risk B-cell acute lymphoblastic leukemia: results of children’s oncology group trial AALL0331. J. Clin. Oncol. 38, 602–612 (2020).

Article  CAS  PubMed  Google Scholar 

Stelmach, P. & Trumpp, A. Leukemic stem cells and therapy resistance in acute myeloid leukemia. Haematologica 108, 353–366 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Depreter, B. et al. Deciphering molecular heterogeneity in pediatric AML using a cancer vs. normal transcriptomic approach. Pediatr. Res. 89, 1695–1705 (2021).

Article  CAS  PubMed  Google Scholar 

Creutzig, U. et al. Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel. Blood 120, 3187–3205 (2012).

Article  CAS  PubMed  Google Scholar 

Barlogis, V. et al. Late cardiomyopathy in childhood acute myeloid leukemia survivors: a study from the L.E.A. program. Haematologica 100, e186–e189 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Taylor, V., Welcher, A. A., Program, A. E. & Suter, U. Epithelial membrane protein-1, peripheral myelin protein 22, and lens membrane protein 20 define a novel gene family. J. Biol. Chem. 270, 28824–28833 (1995).

Article  CAS  PubMed  Google Scholar 

Ng, S. W. K. et al. A 17-gene stemness score for rapid determination of risk in acute leukaemia. Nature 540, 433–437 (2016).

Article  CAS  PubMed  Google Scholar 

Lin, S.-Y. et al. A 6-membrane protein gene score for prognostic prediction of cytogenetically normal acute myeloid leukemia in multiple cohorts. J. Cancer 11, 251–259 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lange, B. J. et al. Outcomes in CCG-2961, a children’s oncology group phase 3 Trial for untreated pediatric acute myeloid leukemia: a report from the Children’s Oncology Group. Blood 111, 1044–1053 (2008).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gamis, A. S. et al. Gemtuzumab ozogamicin in children and adolescents with de novo acute myeloid leukemia improves event-free survival by reducing relapse risk: results from the randomized phase III Children’s oncology group trial AAML0531. J. Clin. Oncol. 32, 3021–3032 (2014).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pollard, J. A. et al. Sorafenib in combination with standard chemotherapy for children with high allelic ratio FLT3/ITD+ acute myeloid leukemia: a report from the children’s oncology group protocol AAML1031. J. Clin. Oncol. 40, 2023–2035 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aplenc, R. et al. Bortezomib with standard chemotherapy for children with acute myeloid leukemia does not improve treatment outcomes: a report from the Children’s Oncology Group. Haematologica 105, 1879–1886 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Balgobind, B. V. et al. Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia. Haematologica 96, 221–230 (2011).

Article  CAS  PubMed  Google Scholar 

Zhang, N. et al. Unraveling the structures, functions and mechanisms of epithelial membrane protein family in human cancers. Exp. Hematol. Oncol. 11, 69 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ariës, I. M. et al. EMP1, a novel poor prognostic factor in pediatric leukemia regulates prednisolone resistance, cell proliferation, migration and adhesion. Leukemia 28, 1828–1837 (2014).

Article  PubMed  Google Scholar 

Wang, J. et al. EMP1 regulates cell proliferation, migration, and stemness in gliomas through PI3K-AKT signaling and CD4. J. Cell. Biochem. 120, 17142–17150 (2019).

Article  CAS  PubMed  Google Scholar 

Hsu, C.-H. et al. Transcriptome profiling of pediatric core binding factor AML. PloS One 10, e0138782 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Ichikawa, H. et al. Common gene expression signatures in t(8;21)-and inv(16)-acute myeloid leukaemia. Br. J. Haematol. 135, 336–347 (2006).

Article  CAS  PubMed  Google Scholar