Perry RL, Satin AJ, Barth WH, Valtier S, Cody JT, Hankins GD. The pharmacokinetics of oxytocin as they apply to labor induction. Am J Obstet Gynecol. 1996;174(5):1590–93.

Article  CAS  PubMed  Google Scholar 

Kenkel W, Perkeybile A-M, Yee J, Pournajafi-Nazarloo H, Lillard T, Ferguson E, et al. Behavioral and epigenetic consequences of oxytocin treatment at birth. Sci Adv. 2019;5(5):eaav2244.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Laughon SK, Branch DW, Beaver J, Zhang J. Changes in labor patterns over 50 years. Am J Obstet Gynecol. 2012;206(5):e4191–9.

Article  Google Scholar 

Talati C, Carvalho JCA, Luca A, Balki M. The effect of intermittent oxytocin pretreatment on oxytocin-induced contractility of human myometrium in vitro. Anesth Analg. 2019;128(4):671–78.

Article  CAS  PubMed  Google Scholar 

Oscarsson ME, Amer-Wåhlin I, Rydhstroem H, Källén K. Outcome in obstetric care related to oxytocin use. A population-based study. Acta Obstet Gynecol Scand. 2006;85(9):1094–8.

Article  PubMed  Google Scholar 

Carter CS, Kenkel WM, MacLean EL, Wilson SR, Perkeybile AM, Yee JR, et al. Is oxytocin nature’s medicine? Pharmacol Rev. 2020;72(4):829–61.

Article  PubMed  PubMed Central  Google Scholar 

Clapp MA, James KE, Bates SV, Kaimal AJ. Patient and hospital factors associated with unexpected newborn complications among term neonates in US hospitals. JAMA Netw Open. 2020;3(2):e1919498.

Article  PubMed  PubMed Central  Google Scholar 

Hinshaw K, Simpson S, Cummings S, Hildreth A, Thornton J. A randomised controlled trial of early versus delayed oxytocin augmentation to treat primary dysfunctional labour in nulliparous women. Brit J Obstet Gynecol. 2008;115(10):1289–95. discussion 95 – 6.

Article  CAS  Google Scholar 

Mirzabagi E, Deepak NN, Koski A, Tripathi V. Uterotonic use during childbirth in uttar pradesh: accounts from community members and health providers. Midwifery. 2013;29(8):902–10.

Article  PubMed  Google Scholar 

Zhang J, Laughon SK, Branch DW. Oxytocin regimen for labor augmentation, labor progression, and perinatal outcomes. Obstet Gynecol. 2012;119(2):381–82.

Article  CAS  Google Scholar 

Harris JC, Carter CS. Therapeutic interventions with oxytocin: current status and concerns. J Am Acad Child Adolesc Psychiatry. 2013;52(10):998–1000.

Article  PubMed  Google Scholar 

Stokholm L, Juhl M, Talge NM, Gissler M, Obel C, Strandberg-Larsen K. Obstetric oxytocin exposure and ADHD and ASD among Danish and Finnish children. Int J Epidemiol. 2021;50(2):446–56.

Article  PubMed  Google Scholar 

Kurth L, Davalos D. Prenatal exposure to synthetic oxytocin: risk to neurodevelopment? J Prenat Perinat Psychol Health. 2012;27(1):3.

Google Scholar 

Kurth L, Haussmann R. Perinatal pitocin as an early ADHD biomarker: neurodevelopmental risk? J Atten Disord. 2011;15(5):423–31.

Article  PubMed  Google Scholar 

Tikkanen R, Gunja M, Fitzgerald M, Zephyrin L. Maternal mortality and maternity care in the United States compated to 10 other developed countries. Commonw Fund; 2020:1–17.

Smallwood M, Sareen A, Baker E, Hannusch R, Kwessi E, Williams T. Increased risk of autism development in children whose mothers experienced birth complications or received labor and delivery drugs. ASN Neuro. 2016;8(4):1759091416659742.

Article  PubMed  PubMed Central  Google Scholar 

Soltys SM, Scherbel JR, Kurian JR, Diebold T, Wilson T, Hedden L, et al. An association of intrapartum synthetic oxytocin dosing and the odds of developing autism. Autism. 2020;24(6):1400–10.

Article  PubMed  PubMed Central  Google Scholar 

García-Alcón A, González-Peñas J, Weckx E, Penzol MJ, Gurriarán X, Costas J, et al. Oxytocin exposure in labor and its relationship with cognitive impairment and the genetic architecture of autism. J Autism Dev Disord. 2022;53(1):66–79.

Article  PubMed  Google Scholar 

Torres G, Mourad M, Leheste JR. Perspectives of pitocin administration on behavioral outcomes in the pediatric population: recent insights and future implications. Heliyon. 2020;6(5):e04047.

Article  PubMed  PubMed Central  Google Scholar 

Lønfeldt NN, Verhulst FC, Strandberg-Larsen K, Plessen KJ, Lebowitz ER. Assessing risk of neurodevelopmental disorders after birth with oxytocin: a systematic review and meta-analysis. Psychol Med. 2019;49(6):881–90.

Article  PubMed  Google Scholar 

Hertz-Picciotto I, Schmidt RJ, Krakowiak P. Understanding environmental contributions to autism: causal concepts and the state of science. Autism Res. 2018;11(4):554–86.

Article  PubMed  Google Scholar 

Monks DT, Palanisamy A, Oxytocin. At birth and beyond. A systematic review of the long-term effects of peripartum oxytocin. Anaesthesia. 2021;76(11):1526–37.

Article  CAS  PubMed  Google Scholar 

Saade GR, Sibai BM, Silver R. Induction or augmentation of labor and autism. JAMA Pediatr. 2014;168(2):190–1.

Article  PubMed  Google Scholar 

Wang C, Geng H, Liu W, Zhang G. Prenatal, perinatal, and postnatal factors associated with autism: a meta-analysis. Med (Baltim). 2017;96(18):e6696.

Article  CAS  Google Scholar 

Gardener H, Spiegelman D, Buka SL. Perinatal and neonatal risk factors for autism: a comprehensive meta-analysis. Pediatrics. 2011;128(2):344–55.

Article  PubMed  PubMed Central  Google Scholar 

Guastella AJ, Cooper MN, White CR, White MK, Pennell CE, Whitehouse AJ. Does perinatal exposure to exogenous oxytocin influence child behavioural problems and autistic-like behaviours to 20 years of age? J Child Psychol Psychiatry. 2018;59(12):1323–32.

Article  PubMed  Google Scholar 

Henriksen L, Wu CS, Secher NJ, Obel C, Juhl M. Medical augmentation of labor and the risk of ADHD in offspring: a population-based study. Pediatrics. 2015;135(3):e672–7.

Article  PubMed  Google Scholar 

Oberg AS, D’Onofrio BM, Rickert ME, Hernandez-Diaz S, Ecker JL, Almqvist C, et al. Association of labor induction with offspring risk of autism spectrum disorders. JAMA Pediatr. 2016;170(9):e160965–65.

Article  PubMed  PubMed Central  Google Scholar 

Wiggs KK, Rickert ME, Hernandez-Diaz S, Bateman BT, Almqvist C, Larsson H, et al. A family-based study of the association between labor induction and offspring attention-deficit hyperactivity disorder and low academic achievement. Behav Genet. 2017;47(4):383–93.

Article  PubMed  Google Scholar 

Miranda A, Sousa N. Maternal hormonal milieu influence on fetal brain development. Brain Behav. 2018;8(2):e00920.

Article  PubMed  PubMed Central  Google Scholar 

Singh A, Yeh CJ, Verma N, Das AK. Overview of attention deficit hyperactivity disorder in young children. Health Psychol Res. 2015;3(2):2115.

Article  PubMed  PubMed Central  Google Scholar 

Xu G, Strathearn L, Liu B, Yang B, Bao W. Twenty-year trends in diagnosed attention-deficit/hyperactivity disorder among US children and adolescents, 1997–2016. JAMA Netw Open. 2018;1(4):e181471.

Article  PubMed  PubMed Central  Google Scholar 

Xu G, Strathearn L, Liu B, O’Brien M, Kopelman TG, Zhu J, et al. Prevalence and treatment patterns of autism spectrum disorder in the United States, 2016. JAMA Pediatr. 2019;173(2):153–59.

Article  PubMed  Google Scholar 

Crespi BJ. Autism as a disorder of high intelligence. Front Neurosci. 2016;10:300.

Article  PubMed  PubMed Central  Google Scholar 

Flegal KM, Kit BK, Orpana H, Graubard BI. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA. 2013;309(1):71–82.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maenner MJ, Shaw KA, Bakian AV, Bilder DA, Durkin MS, Esler A, et al. Prevalence and characteristics of autism spectrum disorder among children aged 8 years - autism and developmental disabilities monitoring network, 11 sites, United States, 2018. Morbidity Mortal Wkly Rep Surveillance Summaries (Washington D C : 2002). 2021;70(11):1–16.

Google Scholar 

Hours C, Recasens C, Baleyte JM. ASD and ADHD comorbidity: what are we talking about? Front Psychiatry. 2022;13:837424.

Article  PubMed  PubMed Central  Google Scholar 

Dalsgaard S, Thorsteinsson E, Trabjerg BB, Schullehner J, Plana-Ripoll O, Brikell I, et al. Incidence rates and cumulative incidences of the full spectrum of diagnosed mental disorders in childhood and adolescence. JAMA Psychiatry. 2020;77(2):155–64.

Article  PubMed  Google Scholar 

Zablotsky B, Black LI, Maenner MJ, Schieve LA, Danielson ML, Bitsko RH et al. Prevalence and trends of developmental disabilities among children in the United States: 2009–2017. Pediatrics. 2019;144(4).

Flenik TMN, Bara TS, Cordeiro ML. Family functioning and emotional aspects of children with autism spectrum disorder in southern Brazil. J Autism Dev Disord. 2022;53(6):2306–13.

Article  PubMed  PubMed Central  Google Scholar 

Picardi A, Gigantesco A, Tarolla E, Stoppioni V, Cerbo R, Cremonte M, et al. Parental burden and its correlates in families of children with autism spectrum disorder: a multicentre study with two comparison groups. Clin Pract Epidemiol Ment Health. 2018;14:143–76.