Phelps NH, et al. Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults. The Lancet. 2024. https://doi.org/10.1016/S01406736(23)02750-2.
Loos RJF, Yeo GSH. The genetics of obesity: from discovery to biology. Nat Rev Genet. 2022;23(2):120–33. https://doi.org/10.1038/s41576-021-00414-z.
Article CAS PubMed Google Scholar
Chong B, et al. Trends and predictions of malnutrition and obesity in 204 countries and territories: an analysis of the Global Burden of Disease Study 2019. EClinicalMedicine. 2003. https://doi.org/10.1016/j.eclinm.2023.101850.
Goossens GH, Blaak EE. Adipose tissue dysfunction and impaired metabolic health in human obesity: a matter of oxygen? Front Endocrinol (Lausanne). 2015;6:55. https://doi.org/10.3389/fendo.2015.00055.
Portincasa P, Frühbeck G. Phenotyping the obesities: reality or utopia? Rev Endocr Metab Disord. 2023;24(5):767–73. https://doi.org/10.1007/s11154-023-09829-x.
Article PubMed PubMed Central Google Scholar
Darci-Maher N, et al. Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease. EBioMedicine. 2023. https://doi.org/10.1016/j.ebiom.2023.104620.
Article PubMed PubMed Central Google Scholar
Aleksandrova K, Egea Rodrigues C, Floegel A, Ahrens W. Omics biomarkers in obesity: novel etiological insights and targets for precision prevention. Curr Obes Rep. 2020;9(3):219–30. https://doi.org/10.1007/s13679-020-00393-y.
Article PubMed PubMed Central Google Scholar
Chen HC, et al. Parapharyngeal fat pad area at the subglosso-supraglottic level is associated with corresponding lateral wall collapse and apnea-hypopnea index in patients with obstructive sleep apnea: a pilot study. Sci Rep. 2019;9(1):17722. https://doi.org/10.1038/s41598-019-53515-5.
Article CAS PubMed PubMed Central Google Scholar
Al-Makhamreh HK, Toubasi AA, Al-Harasis LM, Albustanji FH, Al-Sayegh TN, Al-Harasis SM. Pericardial fat and cardiovascular diseases: a systematic review and meta-analysis. J Evid Based Med. 2023;16(2):178–85. https://doi.org/10.1111/jebm.12542.
Santi D, et al. Does an increase in adipose tissue ‘weight’ affect male fertility? A systematic review and meta-analysis based on semen analysis performed using the WHO 2010 criteria. Andrology. 2023. https://doi.org/10.1111/andr.13460.
Choi H, et al. Plasma protein and microRNA biomarkers of insulin resistance: a network-based integrative -omics analysis. Front Physiol. 2019. https://doi.org/10.3389/fphys.2019.00379.
Article PubMed PubMed Central Google Scholar
Page MJ, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. PLoS Med. 2021;18(3): e1003583. https://doi.org/10.1371/journal.pmed.1003583.
Article PubMed PubMed Central Google Scholar
Chandramouli K, Qian PY. Proteomics: challenges, techniques and possibilities to overcome biological sample complexity. Hum Genomics Proteomics. 2009. https://doi.org/10.4061/2009/239204.
Article PubMed PubMed Central Google Scholar
Oberbach A, et al. Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes. J Proteome Res. 2011;10(10):4769–88. https://doi.org/10.1021/pr2005555.
Article CAS PubMed Google Scholar
Karlsson H, Mörtedt H, Lindqvist H, Tagesson C, Lindahl M. Protein profiling of low-density lipoprotein from obese subjects. Proteomics Clin Appl. 2009;3(6):663–71. https://doi.org/10.1002/prca.200800138.
Article CAS PubMed Google Scholar
Brown KA. Metabolic pathways in obesity-related breast cancer. Nat Rev Endocrinol. 2021;17(6):350–63. https://doi.org/10.1038/s41574-021-00487-0.
Article CAS PubMed PubMed Central Google Scholar
Li Y-J, Zhang C, Martincuks A, Herrmann A, Yu H. STAT proteins in cancer: orchestration of metabolism. Nat Rev Cancer. 2023;23(3):115–34. https://doi.org/10.1038/s41568-022-00537-3.
Article CAS PubMed Google Scholar
Jelski W, Sani TA, Szmitkowski M. Class III alcohol dehydrogenase and its role in the human body. Postepy Hig Med Dosw (Online). 2006;60:406–9.
Sebag SC, et al. ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue. Cell Rep. 2021;37(7):110003. https://doi.org/10.1016/j.celrep.2021.110003.
Article CAS PubMed PubMed Central Google Scholar
Moody L, Shao J, Chen H, Pan Y-X. Maternal low-fat diet programs the hepatic epigenome despite exposure to an obesogenic postnatal diet. Nutrients. 2019. https://doi.org/10.3390/nu11092075.
Article PubMed PubMed Central Google Scholar
Pini T, et al. Obesity significantly alters the human sperm proteome, with potential implications for fertility. J Assist Reprod Genet. 2020;37(4):777–87. https://doi.org/10.1007/s10815-020-01707-8.
Article CAS PubMed PubMed Central Google Scholar
Grande R, et al. Platelet-derived microparticles from obese individuals: characterization of number, size, proteomics, and crosstalk with cancer and endothelial cells. Front Pharmacol. 2019;10:7. https://doi.org/10.3389/fphar.2019.00007.
Article CAS PubMed PubMed Central Google Scholar
Hu C. Aldehyde dehydrogenases genetic polymorphism and obesity: from genomics to behavior and health. Adv Exp Med Biol. 2019;1193:135–54. https://doi.org/10.1007/978-981-13-6260-6_8.
Article CAS PubMed Google Scholar
Boden G, et al. Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals. Diabetes. 2008;57(9):2438–44. https://doi.org/10.2337/db08-0604.
Article CAS PubMed PubMed Central Google Scholar
Benabdelkamel H, et al. Mature adipocyte proteome reveals differentially altered protein abundances between lean, overweight and morbidly obese human subjects. Mol Cell Endocrinol. 2015;401:142–54. https://doi.org/10.1016/j.mce.2014.11.021.
Article CAS PubMed Google Scholar
Kras KA, et al. Obesity modifies the stoichiometry of mitochondrial proteins in a way that is distinct to the subcellular localization of the mitochondria in skeletal muscle. Metabolism. 2018;89:18–26. https://doi.org/10.1016/j.metabol.2018.09.006.
Article CAS PubMed PubMed Central Google Scholar
Abdul-Ghani MA, Jani R, Chavez A, Molina-Carrion M, Tripathy D, Defronzo RA. Mitochondrial reactive oxygen species generation in obese non-diabetic and type 2 diabetic participants. Diabetologia. 2009;52(4):574–82. https://doi.org/10.1007/s00125-009-1264-4.
Article CAS PubMed Google Scholar
Berggren JR, Boyle KE, Chapman WH, Houmard JA. Skeletal muscle lipid oxidation and obesity: influence of weight loss and exercise. Am J Physiol Endocrinol Metab. 2008;294(4):E726–32. https://doi.org/10.1152/ajpendo.00354.2007.
Article CAS PubMed Google Scholar
Cho H, et al. ENOblock inhibits the pathology of diet-induced obesity. Sci Rep. 2019;9(1):493. https://doi.org/10.1038/s41598-018-36715-3.
Article CAS PubMed PubMed Central Google Scholar
Qiao Q, et al. Adipocyte abundances of CES1, CRYAB, ENO1 and GANAB are modified in-vitro by glucose restriction and are associated with cellular remodelling during weight regain. Adipocyte. 2019;8(1):190–200. https://doi.org/10.1080/21623945.2019.1608757.
Article CAS PubMed PubMed Central Google Scholar
Soedarman S, Julia M, Gondhowiardjo TD, Prasetya ADB, Kurnia KH, Sasongko MB. Serum apolipoprotein A1 and B are associated with 6-month persistent and incident diabetic macular oedema in type 2 diabetes. BMJ Open Ophthalmol. 2023. https://doi.org/10.1136/bmjophth-2022-001207.
Article PubMed PubMed Central Google Scholar
Azmi S, et al. The role of abnormalities of lipoproteins and HDL functionality in small fibre dysfunction in people with severe obesity. Sci Rep. 2021;11(1):12573. https://doi.org/10.1038/s41598-021-90346-9.
Article CAS PubMed PubMed Central Google Scholar
Sant’Anna VAR, Izar MCO, Gidlund M, Fonseca HAR, Vaccine Heart Group. Autoantibodies against an immunodominant epitope from apolipoprotein B and risk of cardiovascular events in subjects with type 2 diabetes. Eur J Intern Med. 2023. https://doi.org/10.1016/j.ejim.2023.07.018.
Zhang C, Ni J, Chen Z. Apolipoprotein B displays superior predictive value than other lipids for long-term prognosis in coronary atherosclerosis patients and particular subpopulations: a retrospective study. Clin Ther. 2022;44(8):1071–92.
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