*Department of Neurosurgery

†Department of Hematology

‡Department of Molecular Diagnosis Center, The Third Affiliated Hospital of Kunming Medical University/Yunnan Cancer Hospital, Yunnan Cancer Center, Kunming

§Department of Surgery, Jinping County People’s Hospital, Jinping

∥Department of Emergency, Zhoukou Central Hospital, Zhoukou, China

This study was supported by Youth Project of Science and Technology Department of Yunnan Province (No. 202001BB050041), Yunnan Fundamental Research Projects (202001AY070001-247), Reserve talents of Medical Science in Yunnan Province (H-2018055), and Yunnan Education Department Project (2018JS229).

Available data are sourced from the CGGA database (http://www.cgga.org.cn/) and the TCGA database (https://portal.gdc.cancer.gov/).

H.N. was involved in the majority of study, data statistics and analysis, and drafting and revision of the manuscript. H.C. and X.L. were involved in the conception and design of the study and interpretation of data. Y.C. and Z.C. performed bioinformatics analysis of differential expression analysis. J.L. and F.L. were involved in the acquisition of data capture, and analysis of clinical data. C.S. and P.Z. were involved in experiment supervision and management, data analysis, and revision of the manuscript. All authors critically revised the manuscript and approved the final version of the manuscript.

H.N. and H.C. contributed equally to this work.

The authors declare no conflicts of interest.

Correspondence: Chaoyan Sun, MM, Department of Emergency, Zhoukou Central Hospital, No. 26, East Section of Renmin Road, Zhoukou, Henan 466099, China. E-mail: [email protected]; Pin Zuo, MM, Department of Neurosurgery, The Third Affiliated Hospital of Kunming Medical University/Yunnan Cancer Hospital, Yunnan Cancer Center, No.519, Kunzhou Road, Kunming, Yunnan 650118, China. E-mail: [email protected].