Arfanakis, K., Haughton, V. M., Carew, J. D., Rogers, B. P., Dempsey, R. J., & Meyerand, M. E. (2002). Diffusion tensor MR imaging in diffuse axonal injury. AJNR. American Journal of Neuroradiology, 23(5), 794–802.

PubMed  PubMed Central  Google Scholar 

Arone, A., Ivaldi, T., Loganovsky, K., Palermo, S., Parra, E., Flamini, W., & Marazziti, D. (2021). The burden of space exploration on the mental health of astronauts: A narrative review. Clinical Neuropsychiatry, 18(5), 237–246. https://doi.org/10.36131/cnfioritieditore20210502

Article  PubMed  PubMed Central  Google Scholar 

Bryan CJ. Assessment and monitoring of Astronaut Behavioral Health & Psychological Well-Being Following Long-Duration Exploration Missions. 2017.

Google Scholar 

Burles, F., & Iaria, G. (2023). Neurocognitive adaptations for spatial orientation and navigation in astronauts. Brain Sciences, 13(11). https://doi.org/10.3390/brainsci13111592

Burles, F., Williams, R., Berger, L., Pike, G. B., Lebel, C., & Iaria, G. (2023). The unresolved methodological challenge of detecting Neuroplastic changes in astronauts. Life (Basel), 13(2). https://doi.org/10.3390/life13020500

Clément, G. (2011). Fundamentals of space medicine. Springer Science & Business Media.

Book  Google Scholar 

Clément, G. R., Boyle, R. D., George, K. A., Nelson, G. A., Reschke, M. F., Williams, T. J., & Paloski, W. H. (2020). Challenges to the central nervous system during human spaceflight missions to Mars. Journal of Neurophysiology, 123(5), 2037–2063.

Article  PubMed  Google Scholar 

DeVito, E. E., Salmond, C. H., Owler, B. K., Sahakian, B. J., & Pickard, J. D. (2007). Caudate structural abnormalities in idiopathic normal pressure hydrocephalus. Acta Neurologica Scandinavica, 116(5), 328–332. https://doi.org/10.1111/j.1600-0404.2007.00906.x

Article  CAS  PubMed  Google Scholar 

Doroshin, A., Jillings, S., Jeurissen, B., Tomilovskaya, E., Pechenkova, E., Nosikova, I., et al. (2022). Brain Connectometry changes in space travelers after long-duration spaceflight. Frontiers in Neural Circuits, 16, 815838. https://doi.org/10.3389/fncir.2022.815838

Article  PubMed  PubMed Central  Google Scholar 

Eide, P. K., Rapoport, B. I., Gormley, W. B., & Madsen, J. R. (2010). A dynamic nonlinear relationship between the static and pulsatile components of intracranial pressure in patients with subarachnoid hemorrhage. Journal of Neurosurgery, 112(3), 616–625. https://doi.org/10.3171/2009.7.Jns081593

Article  PubMed  Google Scholar 

Fujita, S., Mori, S., Onda, K., Hanaoka, S., Nomura, Y., Nakao, T., et al. (2023). Characterization of brain volume changes in aging individuals with Normal cognition using serial magnetic resonance imaging. JAMA Network Open, 6(6), e2318153-e. https://doi.org/10.1001/jamanetworkopen.2023.18153

Article  Google Scholar 

Hasan, K. M., Mwangi, B., Keser, Z., Riascos, R., Sargsyan, A. E., & Kramer, L. A. (2018). Brain quantitative MRI metrics in astronauts as a unique professional group. Journal of Neuroimaging, 28(3), 256–268. https://doi.org/10.1111/jon.12501

Article  PubMed  Google Scholar 

Hasan, K. M., Sankar, A., Halphen, C., Kramer, L. A., Brandt, M. E., Juranek, J., et al. (2007). Development and organization of the human brain tissue compartments across the lifespan using diffusion tensor imaging. Neuroreport, 18(16), 1735–1739. https://doi.org/10.1097/WNR.0b013e3282f0d40c

Article  PubMed  Google Scholar 

Heine, L., Soddu, A., Gomez, F., Vanhaudenhuyse, A., Tshibanda, L., Thonnard, M., et al. (2012). Resting state networks and consciousness. Frontiers in Psychology, 3. https://doi.org/10.3389/fpsyg.2012.00295

Hupfeld, K. E., McGregor, H. R., Koppelmans, V., Beltran, N. E., Kofman, I. S., De Dios, Y. E., et al. (2022b). Brain and behavioral evidence for reweighting of vestibular inputs with long-duration spaceflight. Cerebral Cortex, 32(4), 755–769.

Article  CAS  PubMed  Google Scholar 

Hupfeld, K. E., McGregor, H. R., Lee, J. K., Beltran, N. E., Kofman, I. S., De Dios, Y. E., et al. (2020). The impact of 6 and 12 months in space on human brain structure and intracranial fluid shifts. Cerebral Cortex Communications, 1(1), tgaa023. https://doi.org/10.1093/texcom/tgaa023

Article  PubMed  PubMed Central  Google Scholar 

Hupfeld, K. E., McGregor, H. R., Reuter-Lorenz, P. A., & Seidler, R. D. (2021). Microgravity effects on the human brain and behavior: Dysfunction and adaptive plasticity. Neuroscience and Biobehavioral Reviews, 122, 176–189. https://doi.org/10.1016/j.neubiorev.2020.11.017

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hupfeld, K. E., Richmond, S. B., McGregor, H. R., Schwartz, D. L., Luther, M. N., Beltran, N. E., et al. (2022a). Longitudinal MRI-visible perivascular space (PVS) changes with long-duration spaceflight. Scientific Reports, 12(1), 7238.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jillings, S., Pechenkova, E., Tomilovskaya, E., Rukavishnikov, I., Jeurissen, B., Van Ombergen, A., et al. (2023). Prolonged microgravity induces reversible and persistent changes on human cerebral connectivity. Communications Biology, 6(1), 46. https://doi.org/10.1038/s42003-022-04382-w

Article  PubMed  PubMed Central  Google Scholar 

Jillings, S., Van Ombergen, A., Tomilovskaya, E., Rumshiskaya, A., Litvinova, L., Nosikova, I., et al. (2020). Macro- and microstructural changes in cosmonauts' brains after long-duration spaceflight. Science Advances, 6(36). https://doi.org/10.1126/sciadv.aaz9488

Koppelmans, V., Bloomberg, J. J., Mulavara, A. P., & Seidler, R. D. (2016). Brain structural plasticity with spaceflight. NPJ Microgravity, 2, 2. https://doi.org/10.1038/s41526-016-0001-9

Article  PubMed  PubMed Central  Google Scholar 

Koppelmans, V., Mulavara, A. P., Seidler, R. D., De Dios, Y. E., Bloomberg, J. J., & Wood, S. J. (2022). Cortical thickness of primary motor and vestibular brain regions predicts recovery from fall and balance directly after spaceflight. Brain Structure and Function, 227(6), 2073–2086.

Article  PubMed  Google Scholar 

Kramer, L. A., Hasan, K. M., Sargsyan, A. E., Wolinsky, J. S., Hamilton, D. R., Riascos, R. F., et al. (2015). MR-derived cerebral spinal fluid hydrodynamics as a marker and a risk factor for intracranial hypertension in astronauts exposed to microgravity. Journal of Magnetic Resonance Imaging, 42(6), 1560–1571. https://doi.org/10.1002/jmri.24923

Article  PubMed  Google Scholar 

Kramer, L. A., Hasan, K. M., Stenger, M. B., Sargsyan, A., Laurie, S. S., Otto, C., et al. (2020). Intracranial effects of microgravity: A prospective longitudinal MRI study. Radiology, 295(3), 640–648.

Article  PubMed  Google Scholar 

Lee, A. G., Mader, T. H., Gibson, C. R., Brunstetter, T. J., & Tarver, W. J. (2018). Space flight-associated neuro-ocular syndrome (SANS). Eye (London, England), 32(7), 1164–1167. https://doi.org/10.1038/s41433-018-0070-y

Article  PubMed  Google Scholar 

Lee, J. K., Koppelmans, V., Pasternak, O., Beltran, N. E., Kofman, I. S., De Dios, Y. E., et al. (2021). Effects of spaceflight stressors on brain volume, microstructure, and intracranial fluid distribution. Cerebral Cortex Communications, 2(2), tgab022.

Article  PubMed  PubMed Central  Google Scholar 

Lee, J. K., Koppelmans, V., Riascos, R. F., Hasan, K. M., Pasternak, O., Mulavara, A. P., et al. (2019). Spaceflight-associated brain white matter microstructural changes and intracranial fluid redistribution. JAMA Neurology, 76(4), 412–419. https://doi.org/10.1001/jamaneurol.2018.4882

Article  PubMed  PubMed Central  Google Scholar 

Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P., et al. (2009). The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration. Journal of clinical epidemiology, 62(10), e1–e34.

Article  PubMed  Google Scholar 

Lövdén, M., Bäckman, L., Lindenberger, U., Schaefer, S., & Schmiedek, F. (2010). A theoretical framework for the study of adult cognitive plasticity. Psychological Bulletin, 136(4), 659–676. https://doi.org/10.1037/a0020080

Article  PubMed  Google Scholar 

Lövdén, M., Wenger, E., Mårtensson, J., Lindenberger, U., & Bäckman, L. (2013). Structural brain plasticity in adult learning and development. Neuroscience and Biobehavioral Reviews, 37(9 Pt B), 2296–2310. https://doi.org/10.1016/j.neubiorev.2013.02.014

Article  PubMed  Google Scholar 

Macias, B. R., Patel, N. B., Gibson, C. R., Samuels, B. C., Laurie, S. S., Otto, C., et al. (2020). Association of long-duration spaceflight with anterior and posterior ocular structure changes in astronauts and their recovery. JAMA Ophthalmology, 138(5), 553–559.

Article  PubMed  Google Scholar 

Marshall-Goebel, K., Macias, B. R., Kramer, L. A., Hasan, K. M., Ferguson, C., Patel, N., et al. (2021). Association of structural changes in the brain and retina after long-duration spaceflight. JAMA Ophthalmology, 139(7), 781–784.

Article  PubMed  Google Scholar 

Mase, M., Yamada, K., Banno, T., Miyachi, T., Ohara, S., & Matsumoto, T. (1998). Quantitative analysis of CSF flow dynamics using MRI in normal pressure hydrocephalus. Acta Neurochirurgica. Supplement, 71, 350–353. https://doi.org/10.1007/978-3-7091-6475-4_101

Article  CAS  PubMed  Google Scholar 

McGregor, H. R., Hupfeld, K. E., Pasternak, O., Beltran, N. E., De Dios, Y. E., Bloomberg, J. J., et al. (2023). Impacts of spaceflight experience on human brain structure. Scientific Reports, 13(1), 7878.

Article  CAS  PubMed  PubMed Central  Google Scholar 

McGregor, H. R., Lee, J. K., Mulder, E. R., De Dios, Y. E., Beltran, N. E., Kofman, I. S., et al. (2021). Brain connectivity and behavioral changes in a spaceflight analog environment with elevated CO(2). Neuroimage, 225, 117450. https://doi.org/10.1016/j.neuroimage.2020.117450

Article  CAS  PubMed  Google Scholar 

Moghaddam, H. S., Parsaei, M., Taghavizanjani, F., Cattarinussi, G., Aarabi, M. H., & Sambataro, F. (2024). White matter alterations in affective and non-affective early psychosis: A diffusion MRI study. Journal of Affective Disorders, 351, 615–623. https://doi.org/10.1016/j.jad.2024.01.238

Article  PubMed  Google Scholar 

Mokri, B. (2001). The Monro-Kellie hypothesis: Applications in CSF volume depletion. Neurology, 56(12), 1746–1748. https://doi.org/10.1212/wnl.56.12.1746

Article  CAS  PubMed  Google Scholar 

Nabizadeh, F., & Jameie, S. B. (2022). Diffusion tensor imaging (DTI) and plasma p-tau 181 in Alzheimer’s disease. Neurology Letters, 1(1), 21–27. https://doi.org/10.52547/nl.1.1.21

Article  Google Scholar