Heat stress induces IL-1β and IL-18 overproduction via ROS-activated NLRP3 inflammasome: implication in neuroinflammation in mice with heat stroke

aDepartment of Emergency Medicine, Luoding People’s Hospital, Yunfu

bCollege of Continuing Education, Guangdong Medical University, Zhanjiang

cDepartment of Critical Care Medicine

dDepartment of Emergency Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou

eDepartment of Endocrinology, Binhaiwan Central Hospital of Dongguan, Dongguan Hospital Affiliated to Medical College of Jinan University, Dongguan, China

Received 7 January 2024 Accepted 9 April 2024.

*Guoqiang Du, Zixi Yang, and Yin Wen contributed equally to the writing of this article.

Correspondence to Weifeng Li, PhD, Department of Emergency Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 106 Zhongshan Er Road, Guangzhou 510080, China Tel: +86 020 838217812; fax: +86 020 838217812; e-mail: [email protected]

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