Crosbie, E. J., Kitson, S. J., McAlpine, J. N., Mukhopadhyay, A., Powell, M. E., & Singh, N. (2022). Endometrial cancer. The Lancet, 399(10333), 1412–1428. https://doi.org/10.1016/s0140-6736(22)00323-3.

Article  Google Scholar 

Tossetta, G., & Marzioni, D. (2023). Targeting the NRF2/KEAP1 pathway in cervical and endometrial cancers. European Journal of Pharmacology, 941, 175503 https://doi.org/10.1016/j.ejphar.2023.175503.

Article  CAS  PubMed  Google Scholar 

Tossetta, G., Fantone, S., Goteri, G., Giannubilo, S. R., Ciavattini, A., & Marzioni, D. (2023). The role of NQO1 in ovarian cancer. International Journal of Molecular Science, 24(9), 7839 https://doi.org/10.3390/ijms24097839.

Article  CAS  Google Scholar 

Speroff, Leon (1995). Clinical gynecologic endocrinology and infertility: [M]. Williams & Wilkins, 47(2), 42.

Google Scholar 

Weiderpass, E., Adami, H. O., & Baron, J. A. et al. (1999). Risk of endometrial cancer following estrogen replacement with and without progestins. Journal of the National Cancer Institute, 91(13), 1131.

Article  PubMed  Google Scholar 

Amankwah, E. K., Friedenreich, C. M., & Magliocco, A. M. et al. (2013). Anthropometric measures and the risk of endometrial cancer, overall and by tumor microsatellite status and histological subtype. American Journal of Epidemiology, 177(12), 1378–1387.

Article  PubMed  PubMed Central  Google Scholar 

Imran, M., Sachdeva, G., Menon, S., Das, D., Davuluri, S., Acharya, K., & Chaudhari, U. (2023). Therapeutic metformin concentrations positively regulate proliferation in endometrial epithelial cells via mTOR activation and augmented mitochondrial strength. Canadian Journal of Physiology and Pharmacology, 101(1), 52–64. https://doi.org/10.1139/cjpp-2022-0307.

Article  CAS  PubMed  Google Scholar 

Szatrowski, T. P., & Nathan, C. F. (1991). Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Research, 51(3), 794–798.

CAS  PubMed  Google Scholar 

Nishikawa, M. (2008). Reactive oxygen species in tumor metastasis. Cancer Letters, 266(1), 53–59.

Article  CAS  PubMed  Google Scholar 

Tossetta, G., & Inversetti, A. (2023). Ovarian cancer: advances in pathophysiology and therapies. International Journal of Molecular Science, 24(10), 8930 https://doi.org/10.3390/ijms24108930.

Article  Google Scholar 

Tossetta, G., & Mazzucchelli, R. (2022). Pathology of urologic cancers. Cancers, 14(15), 3751 https://doi.org/10.3390/cancers14153751.

Article  PubMed  PubMed Central  Google Scholar 

Tossetta, G., Fantone, S., Marzioni, D., & Mazzucchelli, R. (2023). Role of natural and synthetic compounds in modulating NRF2/KEAP1 signaling pathway in prostate cancer. Cancers, 15(11), 3037 https://doi.org/10.3390/cancers15113037.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kanda, N., & Watanabe, S. (2003). 17beta-estradiol inhibits oxidative stress-induced apoptosis in keratinocytes by promoting Bcl-2 expression. Journal of Investigative Dermatology, 121(6), 1500–1509.

Article  CAS  PubMed  Google Scholar 

Burow, M. E., Tang, Y., & Collinsburow, B. M. et al. (1999). Effects of environmental estrogens on tumor necrosis factor alpha-mediated apoptosis in MCF-7 cells. Carcinogenesis, 20(11), 2057–2061.

Article  CAS  PubMed  Google Scholar 

Tesarik, J., Garrigosa, L., & Mendoza, C. (1999). Estradiol modulates breast cancer cell apoptosis: a novel nongenomic steroid action relevant to carcinogenesis. Steroids, 64(1-2), 22 .

Article  CAS  PubMed  Google Scholar 

Jensen, E. V., & Desombre, E. R. (1973). Desombre, Estrogen-receptor interaction. Science, 182(4108), 126–134.

Article  CAS  PubMed  Google Scholar 

Nadal-Serrano, M., Sastre-Serra, J., & Pons, D. G. et al. (2012). The ERalpha/ERbeta ratio determines oxidative stress in breast cancer cell lines in response to 17beta-estradiol. Journal of Cellular Biochemistry, 113(10), 3178–3185.

Article  CAS  PubMed  Google Scholar 

Laoukili, J., Stahl, M., & Medema, R. H. (2007). FoxM1: at the crossroads of ageing and cancer. Biochimica Et Biophysica Acta, 1775(1), 92–102.

CAS  PubMed  Google Scholar 

Myatt, S. S., & Lam, E. W. F. (2007). The emerging roles of forkhead box (Fox) proteins in cancer. Nature Reviews Cancer, 7(11), 847–859.

Article  CAS  PubMed  Google Scholar 

Park, H. J., Carr, J. R., & Wang, Z. et al. (2009). FoxM1, a critical regulator of oxidative stress during oncogenesis. Embo Journal, 28(19), 2908–2918.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Halasi, M., Pandit, B., & Wang, M. et al. (2013). Combination of oxidative stress and FOXM1 inhibitors induces apoptosis in cancer cells and inhibits xenograft tumor growth. American Journal of Pathology, 183(1), 257–265.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Millour, J., Constantinidou, D., & Stavropoulou, A. V. et al. (2010). FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistance. Breast Cancer Research, 12(1), 1–1.

Google Scholar 

Millour, J., Constantinidou, D., Stavropoulou, A. V., Wilson, M. S. C., Myatt, S. S., & Kwok, J. M. M. et al. (2010). FOXM1 is a transcriptional target of ERα and has a critical role in breast cancer endocrine sensitivity and resistance. Oncogene, 29(20), 2983–2995. https://doi.org/10.1038/onc.2010.47.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wierstra, I., & Alves, J. (2008). FOXM1, a typical proliferation-associated transcription factor. Biological Chemistry, 388(12), 1257–1274.

Article  Google Scholar 

Li, S. K. M., Smith, D. K., & Leung, W. Y. et al. (2008). FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 Expression. Journal of Biological Chemistry, 283(24), 16545–16553.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Halliwell, B. (2007). Oxidative stress and cancer: have we moved forward? Biochemical Journal, 401(1), 1–11.

Article  CAS  PubMed  Google Scholar 

Liang, J., & Shang, Y. (2013). Estrogen and cancer. Annual Review of Physiology, 75(75), 225–240.

Article  CAS  PubMed  Google Scholar 

Subbiah, M. T. (1998). Mechanisms of cardioprotection by estrogens. Experimental Biology and Medicine, 217(1), 23 .

Article  CAS  Google Scholar 

Toran-Allerand, C. D. (1996). Mechanisms of estrogen action during neural development: mediation by interactions with the neurotrophins and their receptors? Journal of Steroid Biochemistry & Molecular Biology, 56(1–6), 169–178.

Article  CAS  Google Scholar 

Eliassen, A. H., & Hankinson, S. E. (2009). Endogenous hormone levels and risk of breast, endometrial and ovarian cancers: Prospective studies. Advances in Experimental Medicine & Biology, 630, 148–165.

Article  Google Scholar 

Sanders, D. A., Ross-Innes, C. S., & Beraldi, D. et al. (2013). Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells. Genome Biology, 14(1), 1–16.

Article  Google Scholar 

Horimoto, Y., Hartman, J., & Millour, J. et al. (2011). ERβ1 represses FOXM1 expression through targeting ERα to control cell proliferation in breast cancer. American Journal of Pathology, 179(3), 1148–1156.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Andrea, T., Daniele, V., & Roberta, M. et al. (2009). Hormonal carcinogenesis and socio-biological development factors in endometrial cancer: a clinical review. Acta Obstetricia Et Gynecologica Scandinavica, 87(11), 1101–1113.

Google Scholar 

Yuan, L., Dietrich, A. K., & Nardulli, A. M. (2014). 17β-Estradiol alters oxidative stress response protein expression and oxidative damage in the uterus. Molecular & Cellular Endocrinology, 382(1), 218 .

Article  CAS  Google Scholar 

Sugioka, K., Shimosegawa, Y., & Nakano, M. (1987). Estrogens as natural antioxidants of membrane phospholipid peroxidation. Febs Letters, 210(1), 37.

Article  PubMed  Google Scholar 

Sastre-Serra, J., Valle, A., & Company, M. M. et al. (2010). Estrogen down-regulates uncoupling proteins and increases oxidative stress in breast cancer. Free Radical Biology & Medicine, 48(4), 506–512.

Article  CAS  Google Scholar 

Behl, C., Widmann, M., & Trapp, T. et al. (1995). 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochemical & Biophysical Research Communications, 216(2), 473–482.

Article  CAS  Google Scholar 

Behl, C., Skutella, T., & Frank, L. H. et al. (1997). Neuroprotection against Oxidative Stress by Estrogens: Structure-Activity Relationship. Molecular Pharmacology, 51(4), 535–541.

Article  CAS  PubMed  Google Scholar 

Nogueira, V., Park, Y., & Chen, C. C. et al. (2008). Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis. Cancer Cell, 14(6), 458 .

Article  CAS  PubMed  PubMed Central